Parkinson 's Disease : Disease

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Jill Moreland Pathology1321 March 25, 2017 PARKINSON’S DISEASE INTRODUCTION: If you eat unhealthy, fatty foods your whole life, you have a higher risk of developing diabetes, cardiovascular disease, or arteriosclerosis. If you have unprotected sex, you may contract a sexually transmitted disease, such as syphilis, gonorrhea, or HIV/AIDS. But, Parkinson’s doesn’t racially discriminate, nor does it care if someone is wealthy, poor, educated, non-educated, male or female. Anyone can develop Parkinson’s disease. The disease begins in the brain, our most intricate, delicate organ, whose complexity is still not entirely understood, even with today’s technology and experts. The brain intrigues me. I find myself curious about brain…show more content…
Identified as LRRK2, this gene mutation only accounts for one to two percent of all cases of Parkinson’s disease. (Michael J. Fox Foundation) PATHOPHYSIOLOGY: Parkinson 's disease is a progressive neurologic degenerative disease of the Central Nervous system. The brain produces Dopamine and Norepinephrine, which are chemicals needed for smooth muscle movement and coordination, heart rate, and blood pressure. Dopamine and Norepinephrine are released by basal ganglions that are produced in a bundle of nerve cells in the brainstem called substantia nigra. In Parkinson 's patients, the substantia nigra are destroyed and neither of the chemicals can be released into the body. (3) The decrease in Norepinephrine causes heart arrhythmia and low blood pressure, causing the person to get dizzy upon standing or tire easily. The lack of Dopamine, the smooth muscle movement and coordination controller is now gone, or significantly decreased, resulting in the first signs of Parkinson’s disease, pill-rolling, a one handed tremor and a decreased appetite. (2) SIGNS & SYMPTOMS: By the time someone shows signs and symptoms of Parkinson 's, Dopamine production in the brain has been reduced by 60 to 80% and is fairly advanced. This results in the most recognizable sign of Parkinson 's disease, the resting tremor of the hand or hands. During deliberate movement, the resting tremor goes away, at first. At rest, the tremor will become exacerbated,

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