Essay about Parkinson’s Disease

Diagnosis of Parkinson’s Disease is extremely important in terms of treating the symptoms before the disease gets worse. It is common for patients with PD to have motor symptoms such as gait disorder, which comes from muscle stiffness/rigidity, bradykinesia, postural imbalance, etc. Gait disorders can generally help determine how far the neurological disorder has affected the motor function and control of the individual. Many physicians in general clinics determine if a patient has PD or if it has progressed through evaluating the patients gait pattern, focused on a direct path walking. The problem with this way of diagnosis is that direct paths would generally require the clinic to have a space of 100-meter length for the patient to walk;

As I stepped into the mud room to take off my bright pink rainboots, I knew something was not normal. As I glided onto the sleek wood floors to grab a crunchy after-school snack, I hear my mom descend down the carpeted stairs slowly, becoming aware that this will not be a normal “how was your day at school” conversation. I raced to the cabinet to grab my fix of Goldfish and I sat down on the floor to get a little snuggle time with my dog before my world was turned upside-down.

Parkinson disease (PD) is one of the most common neurologic disorders. and it affects approximately 1% of individuals older than 60 years old. Parkinson’s disease is a condition that progresses slowly by treatment. In addition, loss of pigmented dopaminergic neurons of the substantianigra pars compacta and the presence of Lewy bodies and Lewyneurites are the two major neuropathologic findings in Parkinson disease (Hauser, 2016).

I whisper to myself as I approach the patient. I need to notice every detail. I must not miss a single word or a single movement. Each detail is a clue and each clue is imperative to solve the case and find the diagnosis. I am Sherlock Holmes and this is my mystery to solve. I take a deep breath.

The path physiology of Parkinson’s disease is the pathogenesis if Parkinson disease is unknown. Epidemiologic data suggest genetic, viral, and environmental toxins as possible

There is also no actual known cause of the disease. But in your case because of the car accident that you had a few weeks ago The MRI that we took of your brain shows that your brain was hit pretty hard and the nerve cells of your basal ganglia have become impaired which means you will start to produce a lot less dopamine. An MRI is a painless test used to see the inside of the body without using X-rays. It uses a large magnet, safe, low- energy radio waves and a computer to produce 2d or 3d pictures. Radio waves are passed into your body and are absorbed by some of the tissues, which in turn retransmit the radio waves. The magnet is then turned on and off. The computer picks up this information and generates a picture. Diseased tissue gives off a different signal from healthy tissue and the machine detects this. The positives of having an MRI is that it provides a detailed picture of any part of the body and also means that some of the less pleasant tests do not have to be done. The negatives of having an MRI are very little, they include, being slightly uncomfortable if you are claustrophobic, otherwise the test should have gone very smoothly. Also because you are over the age of 50 this can come in role of the disease. The damage of your brain and your age a very high risks of developing Parkinson’s. Through our research, our understanding the possible causes of Parkinson’s disease is increasing all the time. We also know that you have Parkinson’s because of the symptoms you have been showing. In This disease there are four categories- tremors, stiffness, slowness of movement, and impaired balance and coordination. The nonmotor symptoms, which are symptoms that are not visible are- memory loss, depression, diminished sense of smell. All of these symptoms develop slowly and gradually progress over time. Also remember that each person is very different and are affected differently and

Parkinson Disease’s (PD) is defined as progressive loss of pigmented neurons or cells in the substantia nigra of the brain. These cells manufacture the molecule dopamine, a chemical responsible for regulating purposeful movements. Moreover, when the dopamine level in the brain depletes by 80 percent, the patient will begin experiencing symptoms of PD. Genetics also play a vital role in Parkinson’s development--mutations in the Leucine-Repeat Kinase 2 are its greatest contributors. Furthermore, dopamine levels progressively drop in patients with the disease; therefore, their symptoms gradually become severe as they age. Parkinson’s symptoms are categorized into primary, secondary, motor, and nonmotor. (Fallon & Cataldo, 2013)

Parkinson’s Disease is a long-term progressive neurodegenerative disease consisting of motor system impairment, neuropsychiatric, and nonmotor features. The disease is characterized by the following key clinical features: bradykinesia, resting tremor, postural instability, and rigidity. These symptoms are due to the diminishing of dopamine in the nigrostriatal pathway and substantia nigra, which causes inhibition of the thalamus decreasing excitatory input to the motor cortex.1 Along with the key manifestations an individual with Parkinson’s Disease will experience problems associated with the disease or the antiparkinson medications. These co-occurring problems are hallucinations, dementia, daytime sleepiness, fatigue, depression, and pyschosis.2 Psychosis is a common problem in Parkinson’s Disease, and is characterized by paranoid delusions and hallucinations that are visual in nature.2 Risk factors for psychosis consists of advancing age, dementia, sleep disorders, and high doses of antiparkinson drugs.1

Parkinson’s Disease is known as one of the most common progressive and chronic neurodegenerative disorders. It belongs to a group of conditions known as movement disorders. Parkinson disease is a component of hypokinetic disorder because it causes a decreased in bodily movement. It affects people who are usually over the age of 50. It can impair an individual motor as well as non-motor function. Some of the primary symptoms of Parkinson’s disease are characterized by tremors or trembling in hands, legs and arms. In early symptoms the tremor can be unilateral, appearing in one side of body but progression in the disease can cause it to spread to both sides; rigidity or a resistant to movement affects most people with Parkinson’s disease,

Parkinson’s disease is a progressive late-onset disorder that affects the nervous system. The part of the brain that is most affected is the substantia nigra which controls balance and movement. Consequently, the most noted symptoms of this disease are tremors, inability to move, stiffness, or reduced coordination and balance. Scientists have identified many genes that contribute to Parkinson’s but also suggest that the nature of the disease comes from both genetic and environmental factors. The genes we know so far are: LRRK2, PARK2, PARK7, PINK1 (PARK6), SNCA, GBA, and UCHL1; the last two are attributed to developing family history of Parkinson’s and not developing the disease in that individual. In the PARK2, PARK6, and PARK7 genes, in order

Imagine a scenario where our countries safety is in danger, and the president has to release our nuclear weapons at a specific time. What would happen if the president freezes, or has tremors and is not able to give the command at the correct time? The role of the President is very important to American society; Parkinson’s inhibits a person from completing daily or strenuous tasks. The video in question argues that Hillary Clinton is in the 1/100 percentile that has been diagnosed with Parkinson’s. Parkinson’s disease is a disorder of the nervous system that affects the movement of the body. Parkinson’s is caused by nerve cell damage in the brain, where brain cells are gradually breaking down and dying. This disease begins at a low rate; this stage is shown through tremors in the individual’s hands. While tremors are the warning signs of Parkinson’s disease, this disease can also cause an individual to have slow movements, rigid muscles, impaired posture or balance, speech change and loss of automatic movements. Some complications that come from Parkinson’s are thinking difficulties, emotional changes, and sleep problems and disorders (Parkinson’s Disease, 2015). The video that we are using in this analysis is Hillary Clinton Illness Revealed, and it was found on YouTube. As a doctor, Ted Noel uses this video to help explore the possibility of Hillary Clinton having Parkinson’s disease. The analysis of Parkinson’s disease and the symptoms it expresses will help us

In “The effects of physical therapy in parkinson's disease”, De Goede, Samyra, Keus, Gert Kwakkel, & Wagenaar describes the effects of physical therapy towards patients with Parkinson’s disease. De Goede et al include both physical therapy approaches, and the medication used to help those with Parkinson’s. Physical therapy (PT) has a great impact for individuals struggling with PD. But the results of Physical therapy do not help a patient completely rid of the symptoms with PD.

disorder that affects 10 million people worldwide. It is characterized by progressive loss of midbrain dopamine neurons in the substantia nigra pars compacta. Neither the molecular mechanism that underlies the pathogenesis of Parkinson’s is fully understood nor preventative and effective treatment is available. In the past few years, epigenetic mechanisms have emerged as potential mediators of environmental factors which cause abnormal epigenetic modifications which have been detected in PD. The term Epigenetics, refers to reversible heritable alterations in gene expression without any changes in DNA sequence. Fundamental mechanism of epigenetic regulation is mainly chromatin modification which is divided into several categories including DNA methylation, histone modification, histone variant, and non-coding RNA. This assignment discusses on recent studies on how epigenetic dysregulation, which modulates gene expression, plays key role in

Parkinson disease (PD) is a progressive neurodegenerative disorder characterized mainly by physical and psychological disabilities. This disorder was named after James Parkinson, an English physician who first described it as shaking palsy in 1817 (Goetz, Factr, and Weiner, 2002). Jean- Martin Charcot, who was a French neurologist, then progressed and further refined the description of the disease and identified other clinical features of PD (Goetz, Factr, and Weiner, 2002). PD involves the loss of cells that produce the neurotransmitter dopamine in a part of the brain stem called the substansia nigra, which results in several signs and symptoms (Byrd, Marks, and Starr, 2000). It is manifested clinically by tremor,

Parkinson’s Disease is a very well-known, incurable, disease of the nervous system. It has many symptoms that are both motor and non-motor. The main symptom of Parkinson’s disease would be tremors of the body and stiffness. One of the believed non-motor symptoms that this article covers is weight change. It has been discovered that patients with non-tremor dominant subtypes are more prone to severe motor symptoms. These types of patients are also shown to succumb to the disease much quicker than those that have tremors. This article depicts if there is any weight change in the patients that are not using any medication; considering that some medicines can have this side-effect.