Parkinson's Disease Patients

Neurology is one of the most unexplored fields in medicine; however, more recently there has been a spike in the amount of research being done in this specialty. This is because people are becoming more interested in neuroscience, including myself. I attended a pre-medical vocational high school, which exposed me to a greater amount of knowledge pertaining to the basics of anatomy and physiology, along with hands-on opportunities in a medical setting. It was here where I realized that I wanted to pursue a career in medicine; however, due to the fact medical field is very broad, I had no set specialty. This changed when I was exposed to the cruel manifestations of Parkinson’s Disease. During, sophomore year of high school, my grandfather passed away due to complications of Parkinson’s Disease. The way that a neurodegenerative disease was able to overtake a person in the manner that it did was shocking, and while it brought me great grief initially, it later intrigued me. I took up an interest in neuroscience and began to do my own research which culminated in various projects and applications throughout the remainder of my time in high school. These experiences have culminated in my decision to work toward a Cell Biology and

Parkinson disease (PD) is one of the most common neurologic disorders. and it affects approximately 1% of individuals older than 60 years old. Parkinson’s disease is a condition that progresses slowly by treatment. In addition, loss of pigmented dopaminergic neurons of the substantianigra pars compacta and the presence of Lewy bodies and Lewyneurites are the two major neuropathologic findings in Parkinson disease (Hauser, 2016).

When people hear the words Parkinson’s disease they think, “Isn’t that what Michael J. Fox has?” For those who are asking, “Who is Michael J. Fox?” He was the character Marty McFly in the “Back to the Future” movie and played on many TV shows. After being diagnosed with Parkinson’s disease, he set up an organization to research Parkinsonism. What the Michael J. Fox Foundation found was that 40 percent of the people living with Parkinson’s disease experience dystonia as an early symptom or a complication of treatment. This is the only blurb you see on the website about dystonia. In fact, it is so much like the other disorders out there that many people have never heard of it. The purpose of this paper is to inform

Ramig and colleagues (2001) performed a study to examine the long-term effects of using Lee Silverman Voice Treatment (LSVT) to improve vocal function in individuals with Parkinson’s Disease (PD). Ramig and colleagues (2001) compared LSVT to received respiratory therapy (RET) to control for extraneous variables. Subjects were recruited from a variety of sources which helped to reduce recruitment bias (Ramig et al., 2001). Individuals with any laryngeal pathology unrelated to PD were excluded from the study (Ramig et al., 2001). All 33 subjects were stratified based on: age, time post-diagnosis, stage of disease, score on the unified Parkinson’s disease rating scale, and clinical ratings on speech and voice severity (Ramig et al., 2001). Subjects were then randomly divided into 2 groups and received either LSVT or RET provided in four one-hour weekly sessions for four weeks (Ramig et al., 2001).

Parkinson Disease (PD) is a neurodegenerative disease symptomized by tremor, muscular rigidity, and slow imprecise movements. Typically, the disease affects middle-aged and elderly individuals. PD is associated with degeneration of the basal ganglia of the brain causing a deficiency of the neurotransmission of dopamine.

Parkinson's disease is a progressive degenerative disorder of the central nervous system that affects the motor system. It is marked by tremor at rest, muscular rigidity, postural instability, and slow, imprecise movement. The most obvious symptoms are movement related, which include; shaking, rigidity, slowness of movement, difficult with walking, balance, and gait. Other motor symptoms include: posture disturbances, such as a decrease in arm swing, a forward flexed posture, and the use of small steps when walking. Speech and swallowing disturbances are also common motor problems that can appear as well to a patient with Parkinson's disease. Young adults rarely experience Parkinson's disease because it is more common to affect

Many people around the world today suffer from Parkinson’s disease and other movement disorders. A movement disorder is a disorder impairing the speed, fluency, quality, and ease of movement. There are many types of movement disorders such as impaired fluency and speed of movement (dyskinesia), excessive movements (hyperkinesia), and slurred movements (hypokinesia). Some types of movement disorders are ataxia, a lack of coordination, Huntington's disease, multiple system atrophies, myoclonus, brief, rapid outbursts of movement, progressive supranuclear palsy, restless legs syndrome, reflex sympathetic dystrophy, tics, Tourette's syndrome, tremor, Wilson disease, dystonia, which causes involuntary body movement, and Parkinson's disease. Parkinson’s disease, Tourette’s syndrome, and tics are one of the most widely known of these disorders, known to impair people of movements and rob them of their lives.

Parkinson’s disease is a progressive disorder that affects the nervous system, specifically the movement. The most common and most notable symptom is the tremor. The tremor is often found in the arm or hand. Symptoms of Parkinson’s have appeared throughout history. In India, as early as 5000 B.C. certain symptoms of Parkinson’s have showed up. Scientists and researchers have developed many treatments and medications for this disease. Although there are these treatments and medications, there is no permanent cure to Parkinson’s. Current research is still being done to find a cure, and they have found that if a person is healthy when diagnosed they have the potential to live as long as someone who is unaffected by this disease. Parkinson’s

Parkinson’s disease can be described as an issue within the nervous system that causes delayed and heavily impacted body motor skills. Sufferers face an intense loss of body movement; they face periods of unstoppable shaking, stiffened muscles, and delayed movement. Parkinson’s is commonly described as a physically impairing disease, but, in reality, it has the ability to have just as much impact on mental capabilities as it has on physical capabilities. Mainly, in the mental realm of impairment, Parkinson’s has a massive impact on emotional health. The disease and the manner in which the symptoms progressively worsen can be seriously detrimental to the well-being of a sufferer. Constantly dealing with the various symptoms and trying to cope

The first new human prion is discovered in almost 50 years. Prions are misfolded proteins that make copies of themselves by inducing others to misfold, they multiply and cause disease. The resulting illness is MSA, a neurodegenerative disease similar to Parkinson's.

An estimated eight million people are living worldwide with Parkinson’s Disease. Parkinson’s is a disease where the nerve cells, called neurons die in your brain. These neurons that die produce a brain chemical, dopamine which is a neurotransmitter. As the neurons die or become damaged the lack of dopamine creates the symptoms and disease. The neurons that die are located in your Substantia Nigra in the brain. The nerve cell affects your entire nervous system. The neurons transmit information to muscles, gland cells, or other nerve cells all over the human body. The neurons in your brain are highly important because they transmit nerve signals to and from the brain. According to Manfredsson, “Neurons are excitable,

Parkinson’s disease is a nervous system disorder that affects movement, speech, and other brain function due to insufficient amounts of dopamine release. It is currently incurable, however there are some treatments that can be given to a patient depending on their symptoms and how severe they are. These treatments are administered to Parkinson’s disease patients with the goal of controlling symptoms and minimizing their affects for as long as possible as the disease progresses. Parkinson’s disease is still being researched however, and many treatments are considered experimental. Current treatments that are being administered include dopamine drugs, speech and physical therapy, and in more severe cases, deep brain stimulating surgery. Moreover,

The Parkinson 's disease (PD) is the second most common neurodegenerative disorder after Alzheimer 's disease (Lang and Lozano, 1998). It affects about 1% of the population with different ethnic backgrounds throughout the world over the age of 65 (Tanner and Goldman, 1996). The aetiology of Parkinson 's disease is not well understood; however, genetic and environmental factors are thought to play a role (Checkoway and Nelson, 1999). Pathologically, PD is characterised by mitochondrial DNA dysfunction leading to degeneration of dopaminergic neurons in the substantia nigra pars compacta (Fig.1) and subsequent reduction in striatal dopamine levels (Longmore, 2014).

Parkinson’s disease (PD) is a neurodegenerative disease which is progressive, incurable and debilitating. The disease is caused by a loss of dopamine producing neurons in the brainstem which leads primarily to motor deficits. In Australia, 1 in 350 people live with PD and the prevalence is quickly growing (Parkinson 's Queensland, 2014). While most of the people diagnosed with PD are over 65 years old, people as young as 30 can develop the condition (Parkinson 's Queensland, 2014). Currently, there is no known cure for the disease and thus treatment options are limited, meaning that those living with PD, will have to manage the condition for the rest of their life.

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by loss of striatal dopaminergic (DA) terminals and progressive degeneration of dopaminergic neurons in the substantia nigra pars campocta (SNpc) [1]. There is growing evidence suggesting the role of chronic, uncontrolled inflammation in many neuro degenerative disorders[4-7] [1-7] and the effect of anti-inflammatory drugs in altering the course of the disease further supports this idea [8][8]. The inflammation in CNS is mostly the result of innate immune response caused my microglia, cytokines and complement proteins [9][9]. The pathological characteristic of PD is deposits of aggregated α-synuclein in intracellular inclusions, called Lewy bodies [2, 3], which can