Parkinson's Disease Research Paper

Research has shown that studying stem cells has provided possibilities for treating neurological disorders. Scientists have performed studies that have allowed blind patients to gain vision again and have also discovered that sustaining the blood-brain barrier could help in diseases such as Parkinson's disease. Many people find stem cell research unhealthy because of the pain women go through when donating. However, stem cell research has advanced people's knowledge tremendously when it comes to neurological disorders.

While attending the Parkinson’s Support Group, I observed and took note of many occurrences throughout the group. There were 18 caregivers/individuals with Parkinson’s in attendance, along with 3 students, the director, and the group leader (a counseling student intern). Each individual diagnosed with Parkinson’s, except for two, was accompanied by their spouse/caregiver. Members of this group sat around a rectangle table with the group leader at the front. The purpose of the group, on that particular day, was to discuss challenges that individuals with Parkinson’s and or caregivers face, activities and ways to cope, and some positive gains after the disability. The type of group that was ran was a support group, as compared to having guest speakers as usual. The Parkinson’s group was open to the

Parkinson's disease affects the way you move. It happens when there is a problem with certain nerve cells in the brain. Normally, these nerve cells make an important chemical called dopamine. Dopamine sends signals to the part of your brain that controls movement. Some conspiracy theories makes us happy by creating a picture where hitler was finally reduced to a trembling, almost rigid person with the mood swings of a woman at her worst PMS, shambling through a burnt, destroyed, and pillaged Nazi regime because he was inflicted by parkinson's disease in the final days of his life. Although it is rumored that hitler really had this disease. It was highly unlikely that he died from it due to the fact that parkinson's disease does not kill by

The use of stem cells can advance drug development, knowledge of disease, patience specific disease treatment, and can bypass the limits of mouse-models for research. According to the National Institute of Health (1), stem cells are unique in the following ways: they can divide and renew themselves for long periods, they are unspecialized, and they can give rise to specialized cell types. The uniqueness of these stem cells allows for the testing of new drugs, cell-based therapies and the study of human development including cancer research. Human stem cell therapies have been used for the treatment of neurological disease in human clinical trials such as Parkinson’s disease (2), spinal cord injury (3,4) stroke (5), and

There is also no actual known cause of the disease. But in your case because of the car accident that you had a few weeks ago The MRI that we took of your brain shows that your brain was hit pretty hard and the nerve cells of your basal ganglia have become impaired which means you will start to produce a lot less dopamine. An MRI is a painless test used to see the inside of the body without using X-rays. It uses a large magnet, safe, low- energy radio waves and a computer to produce 2d or 3d pictures. Radio waves are passed into your body and are absorbed by some of the tissues, which in turn retransmit the radio waves. The magnet is then turned on and off. The computer picks up this information and generates a picture. Diseased tissue gives off a different signal from healthy tissue and the machine detects this. The positives of having an MRI is that it provides a detailed picture of any part of the body and also means that some of the less pleasant tests do not have to be done. The negatives of having an MRI are very little, they include, being slightly uncomfortable if you are claustrophobic, otherwise the test should have gone very smoothly. Also because you are over the age of 50 this can come in role of the disease. The damage of your brain and your age a very high risks of developing Parkinson’s. Through our research, our understanding the possible causes of Parkinson’s disease is increasing all the time. We also know that you have Parkinson’s because of the symptoms you have been showing. In This disease there are four categories- tremors, stiffness, slowness of movement, and impaired balance and coordination. The nonmotor symptoms, which are symptoms that are not visible are- memory loss, depression, diminished sense of smell. All of these symptoms develop slowly and gradually progress over time. Also remember that each person is very different and are affected differently and

Ramig and colleagues (2001) performed a study to examine the long-term effects of using Lee Silverman Voice Treatment (LSVT) to improve vocal function in individuals with Parkinson’s Disease (PD). Ramig and colleagues (2001) compared LSVT to received respiratory therapy (RET) to control for extraneous variables. Subjects were recruited from a variety of sources which helped to reduce recruitment bias (Ramig et al., 2001). Individuals with any laryngeal pathology unrelated to PD were excluded from the study (Ramig et al., 2001). All 33 subjects were stratified based on: age, time post-diagnosis, stage of disease, score on the unified Parkinson’s disease rating scale, and clinical ratings on speech and voice severity (Ramig et al., 2001). Subjects were then randomly divided into 2 groups and received either LSVT or RET provided in four one-hour weekly sessions for four weeks (Ramig et al., 2001).

Stem cells are located in the spinal cord and they are hard to identify (Konstantinos et al., 2008). Human embryonic stem cells have advantages that other cell types do not contain. They have a large capacity for differentiation and for expansion. They also help in remyelination. However, studies have shown that human embryonic stem cell derived oligodendrocyte progenitor cells can help in neuroprotection, homeostatic maintenance, suppressing inflammation, and promoting the regeneration of axons. (Sharp et al., 2010). Most of the neural stem cell potential is in ependymal cells (Meletis et al., 2008). Transplanting these oligodendrocyte progenitor cells just one week after the injury showed widespread oligodendrocyte remyelination throughout the white matter (Keirstead et al., 2005).

Parkinson’s Disease is a very complex and interesting disease. Parkinson’s is a nervous system disorder that disrupts the person’s movement and thinking. Parkinson’s is named after James Parkinson. Parkinson was a doctor from London. He studied many of the symptoms, and at the time, he got little recognition for his studies. He tried to get medical schools to study with him, but they would not listen. He died in 1824, and it wasn’t until 1861, until his studies got attention. The person that recognized Parkinson’s studies was Jean Martin Charcot. He was a French neurologist. He and his colleagues called the disease Parkinson’s Disease after James Parkinson. (http://www.everydayhealth.com/parkinsons-disease/history-of-parkinsons-disease.aspx) 6/10/2009

Parkinson’s disease, a disorder of the central nervous system that affects movement, often including tremors. Parkinson’s disease affects over a million of American lives, which is way more than what affects people who get diagnosed with Lou Gehrig’s disease, multiple sclerosis, and muscular dystrophy. While Parkinson’s disease can not cause death, complications with the surgery can be serious. Parkinson’s disease surgery complications have been put 14th on the list, for causes of death. There is a lot about Parkinson’s disease that people don’t know yet.

Parkinson’s Disease is a very common disorder these days. Over 10 million people live daily with Parkinson worldwide. Parkinson’s Disease was named after an English surgeon James Parkinson who wrote a detailed description essay called Shaking Palsy in 1817. The average age for Parkinson’s Disease is between 45 to 70 years old but you can also have juvenile or young onset as well. Most common symptoms of Parkinson are tremors, bradykinesia or akinesia, or rigidity or stiffness, and balance disorder. Parkinson’s Disease doesn’t have a cure and the cause is unknown it could be a number of things genetics, environmental triggers, age, or gender. Parkinson’s Disease happens because the dopaminergic neuron dies and

Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder affecting approximately 1% of the population over age 60 [1]. It is the second most common neurodegenerative disorder after Alzheimer's disease and is predicted to increase in prevalence as the population ages, imposing a social and economic burden on society [2]. PD is classically characterized by a loss of mesencephalic dopaminergic neurons and the development of Lewy Bodies within the substantia nigra pars compacta (SNpc) [3]. Neurons originating in the SNpc project to the striatum where they activate D1 or D2 receptors to stimulate the direct or indirect pathway of the basal ganglia, respectively. Activation of the direct pathway by dopamine (DA) results in

In this paper I am going to talk about Parkinson’s Disease. I will talk about what it is, how it occurs, the symptoms, any cures/treatments, facts, how the disease affects the levels of organization, what levels it affects, how it affects homeostasis, how the disease disrupts homeostasis, and how the body responds.

Jeff Seal, Kristel Wilson, Karen Haring, Angela Dietsch, Kelly Lyons, and Rajesh Pahwa sought to test the likelihood of increasing speech loudness levels in individuals with PD through group-focused tasks. The LSVT-certified Speech Pathologist and graduate students who conducted this study mimicked the Lee Silverman Voice Treatment (LSVT) as closely as possible to test patient’s loudness levels in the group setting. There are strict guidelines for using the specific LSVT, but the conductors of this study tried to make this a more accessible therapy method while keeping as much intensity of the program as possible. The clinicians kept the loud-focused

The Investigation of a therapeutic implication on metastatic breast cancer with a specialized human neural stem cell that is programed to secrete carboxylesterase combined with activated form of an ionotecan by targeting a specific tumor site and major cytokine involved in mediating susceptibility of neural stem cells to breast cancer cells.

There are many recent and exciting discoveries in the world of nanotechnology, and new studies examining the possibilities of neural regeneration are not the least of them. The Central Nervous System – consisting of the brain and spinal cord – is perhaps the structure most vital for life in the human body. Unfortunately, it also has one of the slowest and most limited rates of natural regeneration. Damage to the brain or spinal cord or loss of nerve tissue due to degenerative diseases can create life-long physical, cognitive, and psychological debilitation. The devastating implications of damage to the central nervous system have given rise to a field of scientists and clinicians aspiring to understand the system and ultimately repair said damage. Meanwhile, technological innovations have brought us ever closer to actually finding a workable cure. There have been developments in chemical and biochemical fields in this matter and the most promising of these approaches are stem-cell-based therapies. Stem cells are simply undifferentiated cells that are capable of differentiating into specialized cells such as nervous tissue and dividing to create more stem cells. Neural stem cells in particular are capable of differentiating into “neurons, astrocytes, or oligodendrocytes.1”