The four most prominent factors that make pathogenic fungi a problem for human health are contributed to fungal characters of adhesion, dimorphism, thermotolerance, and invasion promoting enzymes. All of these factors compound and often incorporate one another to aide in the survival of invasive fungi. Adhesion is a broad category, but due to the variety of entry ways and different sites of attachment fungi can have on a human this gives the potential for high pathogenesis. That is the infection is able to develop because of the different sites available to the fungi as it grows. Other factors that can attribute to the severity of this are things such as suppressed immune systems of the host, type of fungi, and mode of entry/site of entry. Mode of entry is unique because spores of reproducing fungi can be inhaled while other fungal infections may only be contracted through direct contact. With the broad array of niches available to fungi this also expands the possibilities of contact/exposure. For example some fungi are found on food and contact comes through the consumption of this food. Since epidermal infections are often more common, but less pathogenic than internal infections this is often overlooked by medical professionals. …show more content…
Examples of these enzymes are phospholipases and proteinases secreted by Candida fungi. Phospholipases hydrolyze lipids as part of its invasive strategy. Proteinases hydrolyze proteins to gain nutrients. This often is associated with the degree of invasive fungi pathogenesis and virulence (Khan et al. 2010). This factor is incorporated into all of the previously mentioned factors as it promotes growth. Being able to grow and break down compounds for nutrients is vital both in human infection and survival outside of humans where the host may be a plant, different type of organism, or even a soil
The spread of infection requires three elements. The first is; A source of infecting microorganisms: This could be an exogenous infection which arises from microorganisms external to the individual and do not exist as normal flora. They usually have a preferred portal of entry like the gastrointestinal for Salmonella. Another source is endogenous infections which can occur when part of the client’s flora becomes altered and an overgrowth results e.g. Yeasts infection. Second requirement is means of transmission for the microorganism, which also explains the three primary modes of pathogen transmission. For example, vertical transmission is when a pathogen is
A 20-year old male presented to the hospital with: nausea; diarrhoea and fever. Upon examination he had abdominal pain and a tender liver. The patient admitted to eating wild mushrooms, of which he had collected himself, the afternoon before attending the hospital. Laboratory analysis at the time of admission revealed elevated serum ALT (665 U/L) and AST (880 U/L), increased total bilirubin (4.9mg/dL) and an increased prothrombin time (3.11 seconds). Laboratory tests were repeated six hours later and all levels, except AST, were elevated even further; with ALT and bilirubin doubling in concentration and the prothrombin time also doubling. Albumin concentration was also tested and presented normal at both times. The patient was administered a haemodialysis with N-acetylcysteine.
- wounds and breaks in the skin (pathogens enter the body through mucus membranes, nose, mouth, gut, genital urinary track - catheters, or wounds like surgical incisions which can cause e.g. MRSA).
Infections can be spread through many things, these include; food borne infection, person to person, water borne infection, airborne infection, insect borne infection and fomites.
A decrepit, fungus infested, skeleton-man who’s both tormented and controlled by the reproductive organs of a parasitic fungal infection growing on his face. He hides in dark damp places, usually behind his victim’s toilets, muttering gibberish to himself and occasionally wailing out in bursts of intense pain. His victims mainly include children, who’s blood he ingests, then regurgitates back into the bloodstream imbued with infectious fungal spores. Shortly following infection, the victim may begin to display early flu-like symptoms. After about 4 days, several brown to black pigmented regions begin to appear in large patches on the skin and the flu-like symptoms intensify. At 5-6 days, foxfire may begin to emanate from the patches, along
Fungicides are a class of pesticides that are designed to kill or limit the growth of harmful fungi. "Understanding mechanisms of fungicide action and toxicity is important because humans and domesticated animals encounter these pesticides through a wide variety of applications. In agriculture, fungicides are used to protect tubers, fruits and vegetables during storage or are applied directly to ornamental plants, trees, field crops, cereals and turf grasses" (Hasan 2010: 349). It is very easy to inadvertently and indirectly consume fungicides as a result because of their ubiquitous use, even though many of the components of fungicides can be harmful to human health, animal health and to the environment as a whole.
Microorganisms must either attach to, or penetrate one of bodies surfaces. The site through which a microorganism enters the body is called the route of entry. The skin acts as a protective barrier, in order to cause infection the microorganism must break through the protective barrier. they either do this through a natural opening such as the mouth ,nose, ears, eyes, urethra, rectum or vagina, or enter through a unnatural break in the skins surface such as cuts and grazes, bites or scratches. They can also occur through a surgical wound caused by a operation. Also conditions such as psoriasis or eczema cause breaks in the skin which microorganisms can enter.
Lipase is a general class of enzymes that help the body process and absorb dietary facts. Lipase enzymes catalyses the hydrolysis (splitting of a compound by the addition of a water molecule) of the lipids like triglycerides (that cannot be absorbed) to fatty acids and glycerol so the intestine can absorb them. Lipase enzymes work in conjunction with bile, which helps facilitate the work of lipase.
Describe and explain 3 factors relevant to a microbe that can contribute to the spread of an epidemic of an infectious disease.
Distinctions in the micro-organisms structure can be pivotal to not only the function of the pathogen within the body, but also the means by which it may spread.
Mold growth and mildew are intensified during the winter months, especially in Virginia. As the weather gets cooler and wetter, homeowners tend to lock down their homes to keep warm air inside; and if a home has energy efficient treatments, it becomes tightly sealed and insulated. Well-insulated homes are great because they prevent cold air from entering and heat from escaping, but they can also trap moisture and increase humidity levels. Without a circulation of fresh air, airborne spores can increase the likelihood of mold and mildew stains in your home. As mold grows, it compromises the strength and integrity of your structure.
One of the last places you want to run into mold is inside of your fridge. However, your fridge is the perfect place for mold to thrive, with all that moisture inside and the dark quarters. Luckily, with a few basic supplies you’ll be able to eradicate the mold in your fridge.
Pathogens are everywhere. They are in people, animals, and the environment. Pathogens come in a wide variety. The types are fungal, bacterial, viral, and other parasites. All pathogens can be dangerous, but two of them are more dangerous. These two types that more dangerous are fungal and bacterial. While both fungal and bacterial pathogens cause illness, they differ in the way they are transmitted, the way they are treated, and the diseases they cause.
Fungal nail infections (onychomycosis) is a disease in which fungi cause damage and deterioration of the nail. Usually, the disease occurs on the side parts of the nail, as well as on the free edge and leads to discoloration of the nail, which becomes thicker, and yellow and begins to pull away from the nail bed. Gradually, the fungal infection spreads and covers a larger part of the nail. In some cases, fungal infections of the nail can be painful, especially when walking.