Pathopharmacological Foundations for Advanced Nursing Practice

927 Words Mar 12th, 2016 4 Pages


Obesity is an epidemic disease which is increasing in frequency in frequency. It is one of the most common disorders in medical practice and among the most frustrating and difficult to manage. Little progress has been made in prevention or treatment, yet major changes have occurred in our understanding of its causes and implications for health. It is associated with changes in many body systems. The definition of obesity is: a condition of excess body fat. Obesity is measured using Body Mass Index (BMI). BMI is calculated by dividing body mass in kilograms by the square of height in meters, (ie.
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Management and treatment of obesity is a long term and many times lifelong commitment. Pharmacotherapy and bariatric surgery along with life style change is used to treat obesity.
The list of pharmacological treatments approved for weight loss is long. Orlistat, known as Xenical or Alli, can be bought over the counter, works by reducing fat absorption via inhibition of pancreatic lipase activity in the intestine. Appetite suppressants similar to amphetamines, acting on the central nervous system are also commonly used. Among these drugs are: Adipex (phentermine), Meidia (sibutramine hydrochloride), Dexedrine (dextroamphetamine saccharate), and Belvig (lorcaserin hcl). Drugs such as Zonisamide and Topamax (topiramate) which are medications prescribed for seizures and migraines were found to have a side effect of weight loss, loss of appetite, and leaving a bad taste in your mouth when carbonated beverages are consumed. Other drugs used are a combination of two drugs. Qsymia is a combination of phentermine and topiramate. Contrave is a combination of naltreyone, which treats alcohol and drug addiction and bupropion which treats depression and seasonal affective disorder and

4 used to help smokers quit. In order for this drug to be prescribed the patient must have at least one weight related illness such as high blood pressure or type 2 diabetes. ( Although local doctors will prescribe

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