Pathophysiology Of Diabetes Mellitus And Mellitus

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Diabetes Mellitus

Nathalie Dao
Med 2056
VN FT030
Diabetes Mellitus Research Paper
Ms. Annabelle Anglo

The pathophysiology of the two types of Diabetes Mellitus are described by Schilling (2010). Type 1 Non-Insulin Dependent Diabetes Mellitus starts with a viral infection or other triggering condition that forms antibodies that destroy the beta cells within the pancreas. This causes the pancreas’ production of insulin to drop over time. Initially, the body uses the insulin that was already produced, but as the insulin decreases, the cells within the body are not able to receive and use the glucose. The sugar remains in the bloodstream after digestion and the negative effects of hyperglycemia become more damaging. With Type 1, about 90% or the beta cells are killed by the antibodies.
Type 2 Insulin Dependent Diabetes Mellitus is a chronic disease caused by one or more of the following three factors.
• Impaired insulin production within the pancreas, so the body does not have enough to move the glucose into the tissues and cells.
• Incorrect glucose production in the liver.
• The cells resist the insulin, so it cannot attach to the correct receptors.

SIGNS AND SYMPTOMS OF DIABETES MELLITUS, according to the American Diabetes Association (2015) the most basic symptoms of Type 1 and Type 2 DM are:
• The three P’s
 Polyuria -- Urinating often and having to urinate frequently at night
 Polydipsia – Always feeling very
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