Penicillin Against Gram-Bad Bacteria

In 1928, Alexander Fleming discovered that the mold penicillium notatum could be used as an antibiotic. It was not until 1940 that penicillin was derived from the mold to be used to treat disease and sickness. Norman G. Heatley asked a team of scientist to begin working on isolating the ingredient penicillin from the mold itself. In March of 1940, the team withdrew acidified culture

In this reading there was many very interesting facts about penicillin. Penicillin was a breakthrough in the medical field in the 20th century. The scientist Alexander Fleming had accidentally spilled a vile of bacteria on to a plate of bacteria to his benefit he found that is had stopped the growth of bacteria. This accidental discover has benefited everyone in the world because we have to get these shots if we are infected, plus it saved many life’s in world war II. However, Penicillin is considered an antibiotic chemical that is created by living organism to stop the growth of bacteria and prevent an illness if people were to come into contact with this problem. Since the discovery and massive stock piling of this cure it has become less

Penicillin is an antibiotic used in fighting infections. A Scottish scientist named Alexander Fleming discovered penicillin in 1928. One of the first examples of the power

They were working on it around World War II, they believe that the medicine had potential. They wanted to find a way to use the medicine on humans to help reduce the bacteria infections in a wound. When they did find a way, it mass-produced and used in the war. The medicine saved many lives. The scientist Florey, Chain, and Fleming were awarded the Nobel Prize. Fleming was alone credited with the penicillin discovery. Even though the discovery of penicillin was a simple accident, but all the series of events that led up to being a very useful medicine.

While some discoveries occur after years of painstaking research backed by times of frustration and the urge to give up completely, others occur after a mistake in a singular moment. Similar to the finding of X-rays and matchsticks, the discovery of penicillin by Sir Alexander Fleming in 1928 took place due to a complete accident.

In 1928, after the careless mistake of forgetting to clean his dishes, Alexander Fleming discovered penicillin. The scientific community still celebrates his discovery since it was a major breakthrough in science, especially in the antibiotics and fermentation field. Although his discovery changed various scientific fields and it opened the doors for research in areas not studied or considered relevant before, the actual usefulness of penicillin was truly reached until the large scale production of penicillin was achieved. Before its manufacturing penicillin was considered for researching purposes, but after its manufacturing during World War II, it truly became helpful for humanity because it could finally start performing within its antibiotic spectrum.

To begin with, penicillin had two accidental discoveries. “Originally noticed by a French medical student, Ernest Duchesne, in 1896” (Bellis 123). This means penicillin was noticed years before it was actually discovered. Alexander Fleming re-discovered penicillin when “he observed that a plate culture of Staphylococcus had been contaminated by a blue-green mold and that colonies of bacteria adjacent to the mold were being dissolved” (Bellis 123). This is important because penicillin was re-discovered and this time its medical potential was noticed. All in all, the accidental discoveries by Duchesne and Fleming were monumental events that lead to penicillin becoming widely used.

The own Alexander Fleming indicates that the discovery occurred on 28 September 1928 and that this was accidental. I believe that all of us know how the penicillin was discovered: some bacterial cultures were contaminated by the fungus. He observed that a part of one of the cultures the bacterias had been destroyed by one of this pollutant.

Since the inception of penicillin, many synthetic penicillin have been developed to treat problem with resistance”. In addition, penicillin is a class of antimicrobial drug that is used to treat infections including respiratory infections, urinary tract infections, and sexually transmitted disease. Also, they are effective for treating infections of the heart that are caused by bacteria. Beta-Lactam Antibiotics effective in treating polymicrobial infections. They are effective in treating intra abdominal and gynecologic infections. Cephalosporin’s are similar to the penicillin and can be divided into four generations based on the antimicrobial spectrum activity. The first generation were the first class that was utilized and used to treat skin infection, urinary tract infections and preventive measure for surgical procedures The second generation was used to treat community acquired pneumonia, and other respiratory infections. The third was used to treat bacterial meningitis and nosocomial infections (Arcangelo & Peterson,

In 1928 Sir Alexander Fleming discovered penicillin when he left a plate of staphylococcus uncovered on a plate for two weeks. He was a chemist studying enzyme lysozyme, and rarely kept his laboratory clean. Instead of what one would assume would happen if one left a deadly disease unattended, penicillium notatum, similar to the mold on bready, had killed a large portion of the disease the bacteria. Fleming drew the conclusion that penicillin notatum could potentially treat bacterial infections by somehow killing off the bacteria, which led to testing and eventually mass-marketing of the product penicillin. (American Chemical Society, Alexander Fleming Discovery and

One researcher he hired soon after his arrival was Ernst Chain(Pbs 2). Ernst Chain became interested in antibacterial chemicals. He started looking back at old articles written by Fleming concerning Penicillin . The Oxford team, as Florey's researchers have become known(Pbs 2), began experimenting with the penicillin mold. Penicillin mold naturally produces the antibiotic Penicillin. Scientists learned to grow Penicillin mold in deep fermentation tanks by adding a kind of sugar and other important ingredients. After enough grew scientists separated the penicillin product from the mold. Finally it was purified and bottled and eventually used as an antibiotic. They took it one step further than Fleming did, they did not just try it on a petri dish, but injected it in live mice. With controlled experimentation, they found it cured mice with bacterial infections. They went on to try it on a few human subjects and saw amazing

One of the greatest advances in the medical field that are within the microbiology area was the discovery of the penicillin in the 1940s by Alexander Fleming, Professor of Bacteriology at St. Mary's Hospital in London. Although the initial recognition of its therapeutic effects occurred in the United Kingdom, the United States are the ones that turned this limited substance into a widely available medicine by developing a large-scale production of this life-saving

The discovery of penicillin forever changed modern day medicine. Penicillins role in treating infectious diseases impacted clinic healthcare drastically. Bacterias that were once a dead sentence now were no match to this new powerful drug. Lives were saved. Also, the discovery of penicillin opened the way for other new antibiotics to be discovered. The discovery of penicillin was a major turning point in healthcare.

The way that Alexander Fleming discovered the Penicillin was when he came back from his vacation. He noticed he saw a ring around the mold on the dish. “After some experimentation, he found that the ring was bacteria-free, and that the mold was a rare spore called Penicillium notatum, which have wafted on air currents into his lab from another floor.”(By Lane). All because of Alexander Fleming’s discovery of the Penicillin that he

The history of Penicillin’s discovery can be accredited to fate, luck or just poor hygiene. It was Alexander Fleming who happened across Penicillin in September 1928 at St Mary’s Hospital Medical School (Wood 2010, ¶14).