Persistence Hyperinsulinism Case Studies

Satisfactory Essays
rsistence hyperinsulinemic hypoglycemia in infancy (PHHI) is the complex gene disorder and major cause of Hyperinsulinism in infants. It was first identified as a Greek word Nesidioblastosis (islets)in 1938 by George F. Laidlaw. He pointed out those babies who had abnormal or defective pancreas specifically pancreatic beta cell which recognize as producing insulin but some people in 1930s and 1940s found low blood sugar and also noticed an increased level of insulin in the blood . In 1950 Mcquarrie reported that there have been series of children who are having low blood sugar and increase level of insulin and he noted at that time that half of those children were severely brain damage and found that in some communities the death ratio is 1
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