Pertussis Research Papers

Pertussis, commonly known as whooping cough, is a highly contagious respiratory disease caused by a bacterium, Bordatella pertussis. In 2010 it affected 27, 5501 individuals and was responsible for 262 deaths in the United States. Bordatella pertussis colonizes in the cilia of the respiratory tract3 producing uncontrollable coughing with paroxysms (fits) followed with a high pitched intake of air creating a whoop sound, posttussive emesis (cough induced vomiting), and exhaustion.3 These symptoms can last up to 10 weeks.3 Adults can transfer Pertussis to infants who are not fully immunized, subsequently, they are at a greater risk and may have serious complications from Pertussis including pneumonia and death.4

Whooping cough is a respiratory illness caused by bordetella pertussis bacteria. This bacteria attaches itself to the tiny hairs that line the respiratory system. Once it has attached, it will release toxins that damage and inflame respiratory system.

It is a small, fastidious gram-negative bacteria that easily invades respiratory tract producing a number of antigens and toxins such as pertussis toxin (PT), tracheal cytotoxin, filamentous hemagglutin and pertactin that binds and destroys the pharyngeal epithelial cells (Centers of Disease Control and Prevention, Bordatella Pertussis, p 206). As a result, triggers the immune system response. B. Pertussis portal of entry is through the mouth, nose and throat and it is primarily transmitted through direct contact with respiratory droplets with an infected individual or aerosol droplets and rarely fomites (Brunner & Suddarth 2010, p. 2149). Bordatella pertussis is a human disease and adolescents and adults are the main reservoirs (CDC, p. 206). The disease has high infectivity, high pathogenicity and low virulence.

What is pertussis, commonly known as “whooping cough”? Whooping cough is an infection of the respiratory

Pertussis, also known as whooping cough, is an acute and highly contagious disease caused by Bordetella pertussis, a gram-negative

Whooping cough, which is also known as, Pertussis, is caused by infection by the Bordetella Pertussis bacteria. A highly contagious bacterial disease affects the respiratory system and produces spasms of coughing that usually end in a high-pitched whooping sound.

Cause: Whooping Cough, also known as Pertussis, is a highly contagious disease affecting the respiratory system (nose, throat, lungs and airways) and is caused by the bacterium Bordetella pertussis. The ‘whoop’ from the cough derives from the deep breaths at the end of each bout of coughing. Whooping cough is very infectious and affects individuals of all ages.

people are vaccinated and health or medical care is less accessible. Pertussis infects a large number of people yearly, and in part have killed many. Schools are also a place of concern for uninfected children to become infected. According to ("Old college try applying", 2015) schools and day cares have had the most concentrated number of cases of pertussis. Preventative measure are imperative so that children do not get the disease.

It is recognised that the high number of cases identified in recent epidemics was partly due to the increased availability of more sensitive tests and waning immunity (Australian Government Department of Health 2014). Adults are a significant source of infection. Wiley, Zuo, Macartney and McIntyre (2013) revealed evidence from multiple studies of infant pertussis cases indicate that family members, particularly parents, are the source of infection in at least 50% of

Although there are many controversies with vaccines, they can help protect us. Vaccines work by exposing individuals safely to a germ, such as from a particular virus, so their immune system can produce antibodies to fend off a particular virus (Lemmons, 172). Producing immunity from 90 percent to 100 percent of the time, childhood vaccines not only have personal benefits, but also, for entire communities and the future of public health (Childhood).

Some of the vaccinations that are given to infants lead to dangerous things that may have happen to them right there or in the future. According to procon.org there are vaccines that carries life threatening allergic reactions. There are as cases such as kids going into anaphylaxis, itching rash, swellings on the face and mouth, trouble breathing, low blood pressure, seizures, fever, joint pain and stiffness, and even pneumonia. Nvic.org talks about the very first vaccine that was given in 1946 which was the pertussis vaccine. That shot was deadly because the pertussis vaccine killed within minutes given and without any warning or side effects. In 2009, there were over 26,000 babies born, but they didn’t get to see their first birthday

Whooping cough knowingly as pertussis is a cough caused by bacterial infection that gets into your nose and throat. It spreads very easily, but vaccineslike DTaP and Tdap can help prevent it in children and adults.

While a potential study bias included being limited to Europe, many countries were involved which I think is a particular strength in varying the patient population. I think the study achieved its aim although I think it may have valuable to include patients with chronic pertussis and cough for comparison. This would have required to the study to monitor patients beyond its four week post-initial visit follow up. I do not think the study had obvious imperfections beyond the diary logged patient-reported symptoms. However this would have required patients to continuously visit their primary care providers and would still require a degree of

Whooping cough is becoming more common in the community and primarily being spread through school systems. It is a highly contagious respiratory tract infection that is marked by a severe hacking cough followed by a high-pitched intake of breath that sounds like a “whoop”, which is where the name comes from (Mayo, 2016). It is caused by the microbe bordatella pertussis which is a bacterium. These bacteria attach themselves to the cilia that line part of the respiratory tract. People with pertussis usually spread the disease to another person by coughing or sneezing or if they are spending a lot of time near each other and sharing the same breathing space.

Pertussis cases are reported by states to CDC through the National Notifiable Diseases Surveillance System (NNDSS). Both probable and confirmed cases should be reported nationally. The most recent case definition (2014) for pertussis includes, In the absence of a more likely diagnosis a cough illness lasting ≥2 weeks with one of the following symptoms paroxysms of coughing, inspiratory "whoop,” posttussive vomiting, or apnea with or without cyanosis (for infants aged < 1 year who is PCR positive for pertussis and has ≥ 1 sign or symptom and cough duration < 14 days (classified as "probable" case).