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Phantom Limb Pain Case Studies

Decent Essays

The phenomenon of phantom limb pain (PLP) in patients with amputations has always fascinated healthcare professionals. Although this condition is relatively easy to diagnose, the pathophysiology of PLP remains unclear. It is estimated that greater than 80% of patients with a partial or total loss of a limb develop phantom limb pain, which is a type of neuropathic pain that is perceived in the location of the amputated limb. 1 Studies have shown that up to 75% of patients develop pain within the first few days after amputation, however PLP can occur months or even years later. 2-4 It is primarily localized in the distal parts of the missing limb.5 Risk factors for PLP include gender (more common in women), presence of pre-amputation pain, …show more content…

9 PLP was first described as being mostly of psychological origin with the predominant belief that PLP was generated in the ‘patient’s head’. 2 However, the development of diagnostic methods such as neuroimaging has facilitated the exploration of the peripheral and central nervous system changes following an amputation and their contributions to the development of PLP.10,11
Proposed peripheral mechanisms for the generation of PLP include the formation of neuromas following injury to a nerve. These neuromas are thought to generate abnormal activity in the region where the nerve has been injured leading to a potential source of PLP and stump pain. 12,13 Additionally, changes in the dorsal root ganglion where cell bodes show abnormal spontaneous activity, loss of afferent input and increased sensitivity to mechanical and neurochemical stimulation is another proposed peripheral contribution to PLP. …show more content…

It seems that different ways of stimulating the motor and sensory cortices can be effective in relieving pain.17 Furthermore, since these interventions are significantly less costly than pharmacotherapy and surgery, there is a cost effective benefit in treating PLP. It would be interesting to take this one step further with the added development of a home based protocol in which patients would be able to actively participate and manage their PLP in the comfort of their own

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