Pheochromocytomas are neuroendocrine tumors of the adrenal medulla. They are rare tumors that may occur in 0.8 per 100,000 individuals annually. Pheochromocytomas produce and release adrenaline and noradrenaline into the blood. The former hormone cause an increase in heart rate and contractility, while the latter increases systemic vascular resistance. Although paroxysmal hypertension is the most recognised symptom, pheochromocytomas were found to cause hypertension in less than 0.2 percents of overall hypertension cases. Pheochromocytomas are known to be “the 10% tumor”, as 10% of the tumours are extra adrenal, 10% familial, 10% bilateral, 10% paediatric, and 10% malignant.
fat, specially if associated with cystitis that could be incorrectly identified as tumor invasion. Vascular hyperaemia adjacent to the tumor could cause these abnormal signals
Chordomas are cancerous tumors that occur anywhere on the spine. They grow slowly and can metastasize to other areas of the body. Other names for this disorder include CHDM, chordocarcinoma, chordoepithelioma, notochordal sarcoma, and notochordoma. Chordomas are rare and most often occur in people ages 40 to 70. Males are affected twice as often as females. About half of all chordoma cases appear at the base of the spine, while about a third occur at the base of the skull, and the rest appear in the kneck, upper back, or lower back vertebrae of the spine. Chordomas in the spine can cause the back, arms, or legs of the affected individual to feal weak or numb. Chordomas occurring at the base of the skull can cause double vision or headaches. Chordomas on the tailbone result in a large lump and can affect the function of the bladder or bowel..
Another test that one can perform to measure the effect of an adrenal tumor is performing an ACTH test, which measures the level of adrenocorticotropic hormone (ACTH) in the blood. ACTH is a hormone that is produced from the pituitary gland in the brain. Thus by performing the test one can get information about its concentration in the serum. Usually if adrenal mass is influencing the corticosteroid levels the test will show a higher level of cortisol while giving a lower level of ACTH levels.
Abstract Background Subependymal giant cell astrocytoma (SEGA) is the most common central nervous system tumor in patients with tuberous sclerosis complex (TSC). Although these lesions are generally benign and non-infiltrative, they commonly arise in the region of the foramen of Monro, where they can cause obstructive hydrocephalus and sudden death. Methods Surgical resection has been, and presently remains, the standard treatment for SEGAs demonstrating serial growth on neuroimaging in the setting of symptomatic hydrocephalus or progressive ventriculomegaly. Discussion Surgery can be curative; however, not all SEGAs are amenable to safe and complete resection.
These side effects are more common, although your experience may be different – the range of discomfort or pain varies, depending on your response to the medicine and your current health. Talk with your doctor or health teams – they can help you get through this phase of treatment.
PAI results from disease intrinsic to the adrenal cortex, which is the outer layer of the adrenal gland, found on the top of each kidney (Fig.1) (3).
Angiosarcoma Cancer of the Heart What would you do if you had three months or less to live? If you are diagnosed with angiosarcoma it is a really good possibility that you could have anywhere from a month to eleven months to live depending on how serious the cancer is and where it is located. The purpose of my research paper is to inform you, my audience, of angiosarcoma cancer of the heart or also known as cardiac angiosarcoma.
A pheochromocytoma is a rare, usually benign adrenal tumor. It is approximately five to six centimeters in diameter and fifty to two hundred grams and occurs equally in both men and women between the ages of twenty and forty. The adrenal glands are small endocrine glands that distribute the hormones cortisol and adrenaline. Cortisol is responsible for stress response, homeostasis restoration, glucose restoration, and for countering insulin. Adrenaline is responsible for keeping heart rate balance. Though the exact cause of developing a pheochromocytoma is unknown, mutations in genes that are involved in cell growth such as VHL and NF-1 have been linked to the development. Pheochromocytomas secrete epinephrine, norepinephrine, and dopamine.
Neurofibromatosis is a genetic disorder that causes tumors to form in the brain, spinal cord, and nerves. There are 3 types of this disorder. Type 1 usually appears in childhood, while type 2 and 3 appear in early adulthood. Type 3 can cause chronic pain throughout the body. Some cases may not require treatment other than careful observation. Other cases may require chemotherapy, radiation therapy, or surgery. In this essay i will explain the causes of the disorder, symptoms, treatment, and a day in the life of that person
Chordomas usually cause extensive bone destruction of the skull base, best analyzed on CT. CT will also show frequent intratumoral sequestered bone fragments. MRI typically shows a destructive invasive soft tissue mass arising from the clivus. At an early stage, bone expansion indicates that the tumor originates from bone and not adjacent structures. The extension of chordomas is primarily posterior, with involvement of the pontine cistern and, occasionally, of the premedullary cistern. On MRI, posterior extension may show as a thumb indenting the pons and/or of the medulla (fig 37-1). Extension can be upward to the sella turcica, displacing the pituitary gland, downward to the nasopharynx or laterally to the middle cranial fossa. Most chordomas demonstrate T1 signal hypointensity and T2 signal
Apporoximately 100 cases of JGCT have been reported in English literature. It was first described by Robertson et al in 1967 and was given this name by Kihara in 1968 (1, 2). It is seen predominantly in females in second and third decades of life (3-5). Although some cases have been reported in patients who are more than 40 years old (4) as well as in children of less than 10 years age. Most of the symptoms are attributed to hypertension, hypokalemia, hyperaldosteronism and increased renin activity due to secretion by the tumor. These non-specific symptoms are headaches, retinopathy , double vision, dizziness, nausea, vomiting, polyuria and proteinuria (3, 6). Hypertension is mostly present for several years before the diagnosis of reninoma is made. No correlation has been reported of degree or duration of hypertension with tumor size. Three clinical variants have been reported so far: ‘typical variant’ presenting with hypertension, hypokalemia, increased plasma renin secretion and hyperaldosteronism; ‘atypical variant’ presenting with hypertension but without hypokalemia; ‘non-functioning variant’ presenting without hypertension (12). Endoh et al reported a case of non-functioning variant which was discovered incidentally (7). Our patient presented with hypertension, headaches and hypokalemia and increased plasma renin
Hypertension is a common health problem especially among people over age of 60 years. This disease is diagnostic when a patient blood pressure is more than 140 to 159 over 90 to 99. Blood pressure refers to the pressure that blood applies to the inner walls of the Diabetes is an endocrine system disorder that occurs when the body is unable to control or balance the amount of sugar in blood and within bodily tissues. You know that the human body is like a machine, with organ systems that are specialized in certain functions, and interact with each other to allow all vital functions to happen. For the body to stay healthy, it is essential that its internal environment is stable and balanced despite the different changes that can occur inside
Main Content: It has been estimated that more than 35% of adults in Australia are directly or indirectly affected by adrenal fatigue problem. However, most of them are unaware that something is affecting their health.
Adrenal glands are endocrine glands that sit atop the kidneys (Shier et al., 2009). The adrenal glands secrete hormones that increase heart rate, the force of cardiac muscle contraction, breathing rate, elevate blood pressure and blood glucose level. This activity prepares the body foe energy expending action, sometimes called fight or flight responses (Shier et al., 2009).
Adrenal glands, located near the kidneys, secrete several hormones that are activated by the nervous system. These hormones dictate the body’s reaction to stressful situations. Each person secretes a different amount of hormones, therefore affecting behavior in stressful situations differently (Morris & Maisto, 2005).