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Pheochromocytomas

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Pheochromocytomas are neuroendocrine tumors of the adrenal medulla. They are rare tumors that may occur in 0.8 per 100,000 individuals annually. Pheochromocytomas produce and release adrenaline and noradrenaline into the blood. The former hormone cause an increase in heart rate and contractility, while the latter increases systemic vascular resistance. Although paroxysmal hypertension is the most recognised symptom, pheochromocytomas were found to cause hypertension in less than 0.2 percents of overall hypertension cases. Pheochromocytomas are known to be “the 10% tumor”, as 10% of the tumours are extra adrenal, 10% familial, 10% bilateral, 10% paediatric, and 10% malignant.
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