Essay about Physioex 8 Exercise 10: Acid/Base Balance Worksheet

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Respiratory Acidosis and Alkalosis
Activity 1: Normal Breathing

1. At 20 seconds, pH = 7.4
2. At 40 seconds, pH = 7.4
3. At 60 seconds, pH = 7.4
4. Did the pH level of the blood change at all during normal breathing? If so, how? The pH did not change during the normal breathing.
5. Was the pH level always within the “normal” range for the human body? Yes it was.
6. Did the PCO2 level change during the course of normal breathing? If so, how? No it did not change either.

Activity 2a: Hyperventilation – Run 1

1. At 20 seconds, pH = 7.48
2. At 40 seconds, pH = 7.52
3. At 60 seconds, pH = 7.65
4. Maximum pH = 7.65
5. Did the pH level of the blood change at all during this run? If so, how? Yes it did, when the breathing
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Normal
2. What level of [HCO3-] was present in the urine? Normal
3. Why does the blood pH value change as PCO2 changes? Because the PCO2 is directly proportional to the H+ levels which are inversely proportional to the pH level of the blood.
4. How does the blood pH value change as Pco2 changes? The Pco2 binds with the water in the blood to form carbonic acid which then forms H+ and HCO3-. When the H+ increases it causes the blood to become more acidic and lowers the pH, and when the H+ is low the blood pH rises.

Activity 5: Renal Response to Respiratory Alkalosis

1. What level of [H+] was present in the urine at each of these PCO2/pH levels? Pco2- 35/ H+ normal, Pco2-30/ H+ decreased, Pco2-20/H+ decreased
2. What level of [HCO3-] was present in the urine at each of these PCO2/pH levels? Pco2-35/HCO3- normal, Pco2-30/HCO3- elevated, Pco2-20/HCO3- elevated
3. Assuming that enough time has passed for the renal system to fully compensate for respiratory alkalosis, would you expect PCO2 levels to increase or decrease? Would you expect blood pH levels to increase or decrease? The Pco2 levels would increase as the HCO3- is excreted through the urine and the renal system pumps H+ back into the blood. This would cause the pH levels to decrease to within homeostasis range.
4. Which type of breathing resulted in PCO2 levels closest to the ones we experimented with in this activity – normal

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