Pi3p

P3- Suggest strategies to minimise effects of challenging behaviour in health and social care settings

Brian, G, Y., Greenwood, D, A., Fidock, Dennis, E, K., Stefan, H, I. Kappe, P., Alonso, L., Frank, H and Collins, P (2008) “Malaria progress and prospects for eradication.” Journal Clinical Investiment. 118: 1266-1276.

Malaria (also called biduoterian fever, blackwater fever, falciparum malaria, plasmodium, Quartan malaria, and tertian malaria) is one of the most infectious and most common diseases in the world. This serious, sometimes-fatal disease is caused by a parasite that is carried by a certain species of mosquito called the Anopheles. It claims more lives every year than any other transmissible disease except tuberculosis. Every year, five hundred million adults and children (around nine percent of the world’s population) contract the disease and of these, one hundred million people die. Children are more susceptible to the disease than adults, and in Africa, where ninety percent of the world’s cases occur and where eighty percent of the cases

The child may need more help with personal hygiene and have more washes instead of baths

Malaria is a disease that affects nearly 600 million people and causes more than a million deaths a year, the most coming from children under five. This disease is regularly found in more than 100 countries around the world and affects 40% of the world’s population. It is most commonly transmitted by an infected Anopheles mosquito. The most deadly form of malaria is known as Plasmodium falciparum because almost all deaths from malaria are caused by this specific one. Some of the symptoms that are affiliated with this strand of malaria are the destruction of red blood cells along with complications with the kidneys, lungs, and brain. In more serious cases, it can cause permanent neurological effects and even death. As the Nobel Assembly said at the announcement of the Nobel Prize in Physiology or Medicine, “Diseases caused by parasites have plagued humankind for a millennium and constitute a major global health problem. In particular, parasitic diseases affect the world’s poorest populations and represent a huge barrier to improving human health and wellbeing”. Youyou Tu, one of the winners of the prize, discovered Artemisinin, “a drug that has significantly reduced the mortality rates for patients suffering from malaria by killing the malaria parasites an early stage of their development.”

In “Life of Pi” by Yann Martel , Piscine Patel is the protagonist of this story, his rare name came from french word for pool and more specifically, from a pool in paris in which a close family friend loved to swim. An indian boy who is trying to discover who he is, as a kid his name “piscine” but was popularly use but instead classmates had convert it to “pissing” as like urine , Patel wasn't hurt or mad about it , but he didn't wanted people to remember him as “piss”, when the new year started ,Patel had got in front of the class explaining what piscine stands for , he came up with a smart idea of naming himself Pi after the mathematical number 3.14 but some classmates already knew about his “piss” name so it didn't really matter . Pi had

1. The ability to seek out the human liver, which might provide essential fatty acids the plasmodium parasite cannot produce on its own, is one important adaptation of this organism.

1.1 Describe at least two purposes of performance management and their relationships to business objectives.

For the last year and a half, I have had the privilege of studying Toxoplasma gondii (T. gondii), an apicomplexan parasite. This parasite infects an estimated 30-50% of adults worldwide, most of whom are unaware of their infection. Because it is a close cousin of Plasmodium falciparum, the cause of human malaria, it is also considered a model organism for malaria, a disease that claims the lives of over a million people a year. Thanks to this close relationship, a drug-like compound that has efficacy against one organism will likely have efficacy against the other as well. This research experience lead me to develop a great interest in biomedical research, prompting me to continue on in the same laboratory for my Master’s degree, which I

Part One Pi narrates from an advanced age, looking back at his earlier life as a high school and college student in Toronto, then even further back to his boyhood in Pondicherry. He describes how Mr. Adirubasamy, a close friend of his father’s and a competitive swimming champion, taught him to swim and bestowed upon him his unusual name. We learn that Pi’s father once ran the Pondicherry Zoo, teaching Pi and his brother, Ravi, about the dangerous nature of animals by feeding a live goat to a tiger before their young eyes. Pi, brought up as a Hindu, discovers Christianity, then Islam, choosing to practice all three religions simultaneously. Pi’s parents decide to move the family to Canada; on June 21, 1977, they set sail in a

In any experience or situation, people gain just that, experience. An experience will change and shape a person for better or worse. In each of our personal lives we will experience things unlike any other that will contribute to who we are and how we live. In Yann Martel’s Life of Pi, a boy named Pi becomes stranded on a lifeboat with a Bengal tiger. Throughout this book Pi learns how to survive and to coexist with the tiger. Through Pi’s experience, he learns a new appreciation for the small things in life, and for the gifts of god.

Artemisinin-based combination therapies (ACTs) are currently considered gold standard in the management of uncomplicated malaria. For the liver stages, primaquine is the only drug approved to eliminate hypnozoites. Resistance against existing antimalarials is well documented, and troubling due to the emerging resistance to artemisinins. Therefore, a rising incidence of drug resistance requires the development new drugs, with novel disease targeting strategies. Moreover, the challenge is to develop innovative drugs that demostrate (i) faster onset and longer duration of drug action, (ii) safe for children and pregnant women, and (iii) ideally be amenable to a single-dose administration. Following are brief descriptions of such

Watershed Test Answer the following questions on your “Ghetto Scantron Sheet.” When you finish, turn in your test and remain quiet until others are finished. 1. Which of the following lists contain only the EPA’s important beneficial uses for watersheds? A. Agriculture, Urban Development, Drinking water B. Urban Development, Recreation, Fish and Shellfish consumption C. Fish and Shellfish consumption, Aquatic Life habitats, Drinking water D. Swimming, Boating, Canoeing, Rope swinging, Cleaning stuff. What Federal agency is responsible for assessing and monitoring the bodies of water in the U.S.? A. Environmental Precipitation Association B. Environmental Principle Agency C. Environmental Protection Association D. Environmental Protection

There are four species in the Plasmodium Genus that affect humans: P. falciparum, P. vivax, P. ovale, and P. malariae. What people did not know then, was how the protozoan got from

Because of intensive use of antimalarial drugs for several centuries, a serious problem, drug resistance, has emerged for almost all available drugs. Some of these resistances are due to the mutant via drug accumulation and extrusion methods, and some are associated with decrease susceptibility of drug targets. In order to overcome resistance and cross-resistance problem that appearing in most malaria-prevalent regions, a lot of efforts have been made to discover new drugs and new mechanisms of action to treat malaria. In order to decrease the rate of resistance emergence, combination therapies are introduced, which combine two or more available antimalarial drugs that targeting