Pill Loss Investigation

The first thing he or she will need to do is find the bugs that will be needed to complete this experiment and put them in a petri dish.

The purpose of our experiment is to test animal behavior and reactions to a change in environment. Our guiding question is, “Why do living organisms respond to environmental factors?” This is basically a question that is asking why living things will react a certain way to environmental changes. The task to answer this question is to experiment with changing environmental factors with pill bugs.

Some people believe the doctors could care less about their patients getting addicted to the medicines they prescribe to them. The doctors in coal country believe in a “quick fix”, this allows the miners to go back to work rather than get the therapy they need to heel the injury. With the jobs these people have doctors aren’t doing what they’re supposed to do. However, the state became aware and cracked down on prescription rules and opened a prescription drug monitoring program. This program lead to the arrests of multiple doctors and pharmacist. Pill mills were a problem as well. Drug dealers moved in with pills from outside the state making the epidemic even worse. When it started to slow down, the prices rose and they began moving in heroin.

Unfortunately, this topic affects a lot of people, taking away their freedoms. “Among them are… Zondenta McCarter, a sixty six year old woman, a first offender, poor and illiterate, suffering from diabetes, described as naive, trusting and childlike… sentenced to 8 years in prison.” (Schlosser, 4) The author explains that just because she used something once that she’s a dangerous criminal, but if she wasn’t apart of violent crimes she shouldn’t be getting such a harsh sentence. Mark Bennett interviewed some of the criminals, “18 were pill smurfers… single mothers… yet all of them face… sixty to 120 months.” (Bennett, 1-2) None of them were violent crimes, sadly, they get sentences that not only affect them but their families and the world.

Podcast “Race and Medline” talks about how some researchers started to test a drug to see if it can help with heart failure. After they asked the FDA to make this drug into a pill they said no because the research trial was too small. Then they started to think about

This question has many caveats that can determine an answer either way dependent on one’s perspective from either a professional lens or as an information seekers perspective lens, or the average person thinks this could be me maybe I need this? This question is subjective in many ways. As Gregory and Slovic states, for some people the question about prescription drugs rarely arises, however, for to others that face serious health problems this question may arise weekly, or monthly, and the conversation leads to decisions that have weighty effects on the quality and duration of their lives (p.,347). We need to see things form every point of view which makes me believe that it really depends on the patient /consumers point in their lives

In November 2015 Beats by Dre released its first new speaker, Pill+, since its recall of Pill XL due to overheating issues. The Pill+, a tangible good, offers many benefits to its customers. Since Apple acquired Beats in 2014, the new speaker has incorporated some of Apple’s technology into it, such as the charger. The same Lightning cable charger users use for their iPhones can be used to charge the speaker (“Beats new Pill”, 2015). This speaker offers a battery life of twelve hours, which is seven hours longer than the company’s original speaker, the Pill and only takes three hours to charge. With the Beats Pill+ App, customers with both Apple and Android devices can unlock new features. In DJ mode, two users can simultaneously connect their phones to speakers, alternating playing music. (BeatsbyDre, 2016). Customers can also amplify their sound with the app by pairing two speakers wirelessly allowing the music to play from both speakers, which is an upgrade from previous versions that had to be “bumped” with NFC’s tap-to-pair technology (“Beats new Pill”, 2015).

Which has the higher potency? Which has higher efficacy? Please define positive and negative controls and state whether you think their choices fulfill those criteria.

The Second Best Method involves giving one half of the test group the research drug and the other half a placebo. Any beneficial results or side effects the former group exhibits that the control group does not can be attributed to the research drug. Since the control group merely receives a placebo, the members are unlikely to receive any benefits other than more personalized attention from the physician-researchers.

After reading several articles published on this subject, my position is that the pill manufacturer’s

This can range from the patient’s attitude, the doctor and patient relationship, and the actual characteristic of the placebo.

The hygroscopic nature of a drug is a risk for good aerosolization since moisture uptake can result in agglomeration (Hoppentocht et al., 2015). On the other hand, hydrophobic coating improves the flowability of cohesive powders (Hickey et al., 1990; Yang et al., 2005).

Xylitol is an attractive natural sweetener polyol that is commonly used in a variety of pharmaceutical formulations. The most prominent disadvantage of xylitol in pharmaceuticals is its unsuitability for tableting by direct compression. The objective of this study was to develop stable xylitol particles with modified physical properties, improved compactibility and enhanced biopharmaceutical performance without altering its polymorphic form. Xylitol was crystallized using antisolvent crystallization technique in the presence of various hydrophilic polymer additives, i.e., polyethylene glycol (PEG), polyvinylpyrrolidone (PVP) and polyvinyl alcohol (PVA) at a range of concentrations. Crystallized xylitol without additive and xylitol crystallized in the presence of PVP and PVA demonstrated significant improvement in hardness of directly compressed tablets; however, such improvement was not observed for xylitol crystallized in the presence of PEG. Crystallized xylitols produced enhanced dissolution profiles of indomethacin in comparison to parent xylitol. The influence of additive concentration on tablet hardness was dependent on the type of additive, whereas an increased concentration of all additives brought an improvement in the dissolution behaviour of indomethacin. The highest total desirability was achieved from xylitol crystallized in the presence of the highest concentration of PVP (1.2% w/v).The crystallization process did not influence the stable polymorphic form or

Table: 33 Evaluation of Bilayer Tablets of Metoprolol Succinate SR and Hydrochlorothiazide IR (F-6 to F-10)

The study was performed to improve the compactibility and the biopharmaceutical performance of xylitol by improving its physicomechanical properties to make it better suited for tableting using direct compression. To this end, antisolvent crystallization technique was employed in the presence of various additives, i.e., polyethylene glycol (PEG), polyvinylpyrrolidone (PVP) and polyvinyl alcohol with a molecular weight (PVA22000) or 16000 (PVA16000) at varying concentrations (0.06%, 0.3%, 0.6% and 1.2%, w/v). The size and morphological changes induced by crystallization the in presence of the additives were studied. The dissolution performance of crystallized xylitols formulated with a model poorly water-soluble drug, i.e. indomethacin, in comparison to commercial xylitol were also evaluated.