Pneumonia: Immune System and Tiny Air Sacs

Pneumonia is an acute infection of the lungs, it can be caused by a variety of organisms entering the body – including bacteria, viruses or fungi. The infection causes an inflammation of the alveoli (air sacs) of the lungs and may result in the alveoli filling with fluid or other purulent material (Mayo Clinic, 2016). An accumulation of fluid within alveoli and portions of the lungs, can reduce the ability of the lungs to allow for oxygen diffusion across the alveoli walls. If oxygen saturation is low, it can cause the body’s cells to not work effectively. Therefore, the risk of the infection spreading through the body is increased – it is due to this reason, that pneumonia can be life-threatening (American Lung Foundation, 2016). Pneumonia

* Pneumonia is refers to an infection in the lungs that causes swelling in the lungs tissue and this inflammation

Pneumonia is an infection of the lungs. Many different organisms can cause it, including bacteria, viruses, and fungi. Pneumonia can range from mild to severe, and can even be deadly. The severity depends on the type of organism causing pneumonia, as well as your age and underlying health.

Ventilator - associated pneumonia (VAP) is the second most common hospital acquired infection (HAI) and is associated with high morbidity and mortality rates for ventilated patients in intensive care units (Bingham, Ashley, Jong, & Swift, 2010). The VAP increases patients’ mortality rates, length of stay and hospital costs (Hiner, Kasuya, Cottingham, & Whitney, 2010). The VAP is the leading causes of death due to nosocomial infections and the

When CAP occurs, it is determined if the need for hospitalisation is necessary as it depends on the seriousness of the infection. Gram- positive organisms such as S. pneumoniae, naturally occur in the upper respiratory tract, is one cause of lower respiratory infections such as pneumonia, but is also a culprit in causing upper respiratory infections like otitis media. H. influenzae is just one of many bacterial infections that can result in CAP, it therefore can be subacute and present with a low-grade fever and a persistent cough for a few weeks before a patient has a diagnosis. Adults that have very little or no immunity are an easier target for certain viruses such as that of the Cytomegalovirus, which is a viral pathogen that is commonly contracted within the community, other common virus are adenovirus and herpes simplex. When a virus starts to become acute, it starts an infection within the ciliated cells within the airway. When pneumonia occurs from this viral infection, the inflammatory action starts to seep into the alveolar areas and leads to the problem of excess exudation and oedema within the respiratory tract. It is sometimes often difficult to differentiate symptoms of a viral pneumonia from that of bacterial pneumonia (Smeltzer &

Pneumonia is a disease that affects the respiratory system. Specifically, it is an inflammation of the lungs that can be caused by fungi, bacteria, viruses and parasites. Microscopic sacs in the lungs (Alveoli) become inflamed and fill up with fluid, which causes symptoms such as cough, fever, chills and trouble breathing. It is a lung disease that kills thousands every year and hospitalizes many more. Pneumonia is more serious and can be deadly for infants and elderly. This disease has personally affected me when my son was hospitalized with it for 5 days. He was only 10 months old at the time and was admitted with diagnosis of Pneumonia, low oxygen and dehydration.

Pneumonia is described in Tabers cyclopedia medical dictionary, “as inflammation of the lungs, usually due to an infection with bacteria, viruses, or other pathogenic organisms” (p.1833)

According to the University of Virginia (n.d.) in the radiographic findings seen in patients with pneumonia are airspace opacity, lobar consolidation, or interstitial opacities; pneumonia is a space occupying lesion without volume loss (University of University, n.d.).

The client’s secondary diagnosis is community-acquired pneumonia. Typically, immune defense mechanisms, such as the secretion of alveolar macrophages and immunoglobulins A and G, protect the lower airway from infection. Streptococcus pneumoniae, the most common causative agent of community-acquired pneumonia, invades the lungs. The organism triggers an inflammatory response, resulting in increased blood flow and vascular permeability. Neutrophil activation occurs, to surround the kill the invading organism. A combination of the offending organism, neutrophils and fluid from the surrounding blood vessels flood the alveoli, inhibiting normal oxygen transportation. This filling of the alveoli may lead to tachypnea, tachycardia and dyspnea. Further obstruction of airflow and an increased impairment of gas exchange occur as mucous production increases. When

Pneumonia is a serious infection of the lungs. This is when the air sacs in the lungs become inflamed and fill with pus and other liquid, which make it difficult for oxygen to reach the blood through them. If there is too little oxygen in the blood, then the body’s cells cannot work properly. Pneumonia can cause lack of oxygen and the spread of infection through the body, which may lead to death. An annual flu shot can provide protection against Pneumonia since it is similar to

Pneumonia is an inflammation of the lung which results into an excess of fluid or pus accumulating into the alveoli of the lung. Pneumonia impairs gas exchange which leads to hypoxemia and is acquire by inhaling a contagious organism or an irritating agent. (Ignatavicius & Workman, 2013). Fungal, bacteria and viruses are the most common organisms that can be inhale. Pneumonia could be community-acquired or health care associated. Community –acquired pneumonia (CAP) occurs out of a healthcare facility while health care associated pneumonia (HAP) is acquired in a healthcare facility. HAP are more resistant to antibiotic and patients on ventilators and those receiving kidney dialysis have a higher risk factor. Infants, children and the elderly also have a higher risk of acquiring pneumonia due to their immune system inability to fight the virus. Pneumonia can also be classified as aspiration pneumonia if it arises by inhaling saliva, vomit, food or drink into the lungs. Patients with abnormal gag reflex, dysphagia, brain injury, and are abusing drug or alcohol have a higher risk of aspiration pneumonia (Mayo Clinic, 2013). In the case of patient E.O., this patient had rhonchi in the lower lobe and the upper lobe sound was coarse and diminished. Signs and symptoms of pneumonia include difficulty breathing, chest pain, wheezing, fever, headache, chills, cough, confusion, pain in muscle or

pneumoniae and there chemotactic signals and the host cell’s alternate pathway, invade the alveoli. Also red blood cells are recruited to this site. In the third stage, mostly neutrophils are packed into the alveoli and very few bacteria remain. In the final stage, macrophages eliminate the remaining residue from the inflammatory response. As one can see, the damage which is done to the lung is largely a result of the host’s inflammatory response, which causes the build up of fluids in the lungs. If S. pneumoniae is allowed to persist in the lungs it can then invade the blood, which causes bacteremia. When in the blood it can traverse the blood-brain barrier and infect the meninges, which results in meningitis. S. pneumoniae is also associated with diseases in other parts of the respiratory tract including the paranasal sinuses, which is better known as sinusitis, and the middle ear can become infected, which is known as otitis media. It has also been known to cause peritonitis, an inflammation of the peritoneum, the membrane that lines the abdominal wall, and it is also implicated in causing arthritis.

Pneumonia is an illness of the lower respiratory tract in which the lungs become inflamed and congested and alveolar spaces are filled with fluid and cells-polymorphs and lymphocytes (Mandell L.A). It is an inflammatory condition of the lung and it is one of the most serious infections, causing two million deaths annually among the young and elderly. Pneumonia is the largest killer, accounting for 28% to 34% of all child deaths below five years of age in low-income countries and is an important cause of mortality in the elderly in high-income countries (Suárez).

The clinical manifestations of pneumonia will be different according to the causative organism and the patient’s underlying conditions and/or comorbidities (Smeltzer, et al). Some of the manifestations are

Pneumonia is an inflammation or infection of the lungs most commonly caused by a bacteria or virus. Pneumonia can also be caused by inhaling vomit or other foreign substances. In all cases, the lungs' air sacs fill with pus , mucous, and other liquids and cannot function properly. This means oxygen cannot reach the blood and the cells of the body.