Polio : An American Story

Polio an American story is a scholarly readable and informative book which covers the lives of many American eminent scientists who struggled a lot to eradicate polio. This book mainly focuses on the mid twentieth century where the people are very eager to find a vaccine to eradicate polio .This book also covers the entire topics from appearance of polio symptoms to post polio syndrome which shows the valuable thesis done by David M. Oshinsky.

Paralytic poliomyelitis, "polio", held a reign of terror over this nation for decades. But unless you were born before 1955, polio may seem to be just another ephemeral disease that has been nonexistent for years. Those born before 1955 remember having a great fear of this horrible disease which crippled thousands of once active, healthy children. This disease had no cure and no identified causes, which made it all the more terrifying. People did everything that they had done in the past to prevent the spread of disease, such as quarantining areas, but these tactics never seemed to work. Polio could not be contained. Many people did not have the money to care for a family member with polio. This was one of the

In addition to health-related advances, such as the artificial heart valve, DNA structure decay, penicillin, and antibiotics. As well, we can not forget the start of the fight with cancer by the memorable world’s first cancer treatment with Cobalt-60 radiation. Although, new surgical procedures were introduced like the first successful kidney transplant and immunizations like typhoid, smallpox, tetanus, and polio vaccines. Polio epidemics had been occurring in the United States since 1916 according to the Centers for Disease Control and Prevention. The viral disease struck even important figures as President Franklin Roosevelt that forced him to use a wheelchair and wear steel braces on his legs privately. “In the 1940s and 1950s, widespread polio epidemics terrorized the nation. Finally, research scientist Jonas Salk developed an injectable vaccine to prevent polio. In 1955 the vaccine became available to the general public. American scientist Albert Sabin then developed an oral vaccine for polio. Safer and more convenient than Salk’s injection vaccine, the Sabin vaccine became the most common method for preventing the disease. The threat of polio nearly disappeared and many more diseases no longer affected the American people” (Appleby, Joyce 2004). Therefore, the treatments and cures of several epidemics and diseases were an important factor that caused the Baby Boom due to the decrease in the children’s mortality rates and their possibility to reach adult

Throughout the years, there have been many serious diseases that plagued the world, a number of which have been eradicated through the widespread administration of vaccinations. In the 1950s, the number of polio cases in the United States was at 58,000, and in 1988, this disease had affected 350,000 people (11 Facts About Polio). Because polio mainly affects children under the age of five, it became very important to parents that something was done to cure and protect their children. When the polio vaccine was created, doctors were able to administer it to people across America, eventually erasing the virus from the country. While the majority of parents in the United States agree that vaccinations should be mandatory for children (excluding certain children with medical conditions preventing vaccination), there are a growing number of parents choosing to take a stand against these rules. Vaccinations are important because when they are administered, the child becomes protected against the diseases, resulting in fewer cases of contraction. In order to protect the children and adults of the United States from many potentially life-threatening illnesses, vaccinations should be mandatory for every able-bodied child.

As parents are refusing to vaccinate their children against these “long-gone” diseases due to the concern for the vaccine’s safety, they are opening the doors for those diseases like polio and measles to devastate the whole American community once again. These parents react this way because they have different realities. For example, every american back when Franklin D Roosevelt was alive knew what polio was and what it was capable of due to the effect that it had on a nation's president. Nowadays, parents are drawn to campaigns on the safety of vaccinations because of celebrities or other personalities that are protesting against vaccinations due to personal negative experience with expressed vaccine. Since many parents nowadays have not had any personal experiences with most vaccine-preventable diseases they are quick to act when, for example, Jenny McCarthy speaks up about the possibility that autism can be caused by today's vaccinations because many americans have had personal experiences with this disease or are more familiar with this disease since it is widely covered in recent media.

Heather Green Wooten’s The Polio Years in Texas: Battling a Terrifying Unknown chronicles the history of polio in Texas in a very extensive timeline. The book goes all the way back to the beginning of the polio epidemic and essentially progresses to the present. The time in this book certainly exceeds that of, The Captured and Isaac’s Storm. The Captured chronicled a long period of captivity, but did not appear to exceed a decade. Isaac’s Storm traced the initial development of Weather Bureau and covered a great period, but did not exceed that of The Polio Years. Several themes begin to emerge further into the book. Obvious themes included, the support for March of Dimes, impact on families affected by polio, the growth and development of rehabilitation facilities, and more importantly the response to the disease by Texans. Oddly, Wooten discusses the fact that other diseases such as, measles, diphtheria, and tuberculosis took more lives than Polio. However, people feared Polio more than the rest. Wooten attributes polio’s terrifying affect to the uncertainty. Several uncertainties such as, how to prevent it, why did some become crippled, why did some die, and why did it only essentially affected children made polio very terrifying in the 20th century. Texas appeared to have been hit the hardest in comparison to other states. Wooten’s research examined the time during and then after World War II. During this period, Texas saw an immense amount of polio contractions. Per

Polymyelitis, otherwise known as polio, was one of the most feared diseases of the early to mid twentieth century. This disease either killed or it paralyzed its’ victims. This affected America in such a terrible way by killing or paralyzing thousands of them within the beginning of the twentieth century alone, scaring most other Americans and putting up a red flag for most health organizations. President Roosevelt, however, conceived the idea of initiating the charity that would later

With a substantial amount of preventive healthcare advancements behind them, the American medical community turned its attention to the deadly polio virus plaguing America. From 1937 to 1952, known cases of Americans contracting polio skyrocketed from ten thousand to a staggering figure of roughly fifty-seven thousand cases. Of those cases within that time period, approximately one thousand five hundred deaths as a result of polio were recorded. In the year 1953, The National Foundation for Infantile Paralysis provided the scientist Dr. Jonas Salk with the tools necessary to research, and develop a working vaccine to combat the devastating polio disease. After much trial and error, Dr. Salk was finally able to create what he felt was a successful polio vaccination, and proceeded to conduct a field test. After resounding success, manufacturing instructions for the Salk vaccine were sent to a series of scientific laboratories for immediate production and administration to American children. The disaster that occurred next will forever be known through American medical history as the Cutter Incident (named so after one of the labs that administered the polio vaccine). This medical crisis sent shockwaves throughout America and the medical community, and numerous lawsuits were filed against Cutter Laboratories, resulting in fewer and fewer labs willing to accept contract work in developing vaccines.

Roosevelt became president with infantile paralysis (polio), which was diagnosed in 1921, and the public found out.9 Having the American people's president seem weakened by such a disease but push on through expectations showed that little to nothing was going to get in his way and stop him.10 Including FDR's case, close to 25% of those age 21 and older had paralytic cases by the early 1950s.11 Before the vaccine, there was a peak of about 50,000 cases of polio in 1953.12 Concern of the people was also around it's highest point due to the increasing risk of the horrid disease most feared at this time. Hopes for a solution were still going strong. Friends, family, and even strangers kept prayers for those in need. Anything that could be done was done until the vaccine was established. There were even several hundred thousand children placed in a control study and out of the 749,000, only 33 from the vaccinated group developed paralytic polio.13 In addition to this trial and other performed, and conclusion was drawn stating that the vaccine was 80-90% effective against the paralytic branch of polio.14 Chances for a new beginning were showing up all over with this vaccine, even if it only helped those who haven't been diagnosed

The discovery of a chemical made by Canada was used to treat and cure Polio through a joint effort between USA and Canada. Canada developed a more effective oral vaccine after The United States drug trial caused severe backlashes. A graph published by Dr. Christopher J. Rutty visually depicts polio incidents till 1962 portrays the rates after each vaccine, like the Salk and Sabin vaccine made by United States and Canada respectively (Rutty). The graph shows a major decrease in Polio incidents after Canada created the Sabin vaccine in order to counteract the severe polio backlash caused by USA’s drug that was accidentally inactivated and caused polio instead of curing it. The graph is a major indicator that Canadian doctors working on the vaccine were extremely diligent and smart when working on the creation of the Sabin vaccine (the Canadian oral vaccine). The graph also signifies the speed at which Canada was able to release an effective cure for the backlash of the Salk vaccine (USA’s version of the polio vaccine) indicating, Canada was a growing nation in the 1970s in medicine. The creation of the Sabin vaccine led to copious numbers of Polio organizations in Canada doing worldwide care after a national vaccine was found. Canada’s role in the treatment of polio had resonating effects worldwide as a result. Canadian female doctor Vera Peters

The Public Health Lessons of Living with Polio Despite diseases contributing to overall life expectancy, diseases come in all different pathogens, strains, and accompanying symptoms, diseases have impacted how and where we decide to live, our economies, our values, and our daily rituals. Many of the lessons of public health can be attributed to historical events or even ordinary citizens living in society. This paper will identify the struggles and successes of Paul Alexander as well as identify the socio-economic factors that both benefited and hindered the success of Paul Alexander's life. When Paul Alexander first woke up in an iron lung at the age of six, he thought he was dead.

The discovery of the polio vaccine was an important medical and scientific breakthrough because it saved many lives since the 1950s. In the summer of 1916 the great polio epidemic struck the United states. By the 1950s hundreds of thousands of people had been struck by the poliomyelitis. The highest number of cases occurred in 1953 with over 50,000 people infected with the virus.

In February 2013 nine female polio vaccination workers in Nigeria were killed. This tragic incident sheds some light on resistance to vaccinations. Ten years ago Nigerian religious leaders told citizens that vaccines were unsafe, that they caused sterility. Polio is close to becoming the second disease successfully eliminated due to vaccines. Less than 250 cases of Polio were reported last year worldwide. Polio can only be eliminated if Nigeria stops resisting and if South Asia does the same ("The Dangers of Vaccine Defiance [analysis]."). Polio is still a problem in Nigeria, even though it’s not in America. Given the amount of international travel and immigration, to not vaccinate is to risk the chance of young children getting a deadly disease. (Offit) Polio causes permanent paralysis in one in every 200 cases and death in a tenth of those cases. The Global Polio Eradication Initiative (GPEI) claims that 10 million children have been saved from paralysis due to vaccination. Vaccinations save 10 million lives every year. Many

“A 1916 Polio epidemic in the United States killed 6,000 people and paralyzed 27,000 more” (“Polio Vaccine”). This lead to the creation of the polio vaccine that has helped to prevent polio for a very long time. The IPV and OPV vaccines played a huge role in all of this. Jonas Salk, who created the IPV vaccine and Albert Sabin, who created the OPV vaccine saved millions of people all around the world from polio (Petersen, Jennifer B). The IPV and OPV polio vaccine helped eliminate polio from the United States and helped prevent polio in other parts of the world (“Polio Vaccine”).

The similarity between the poliovirus and already solved plant virus’s led to a better understanding of how the poliovirus can regenerate within a host. Although the virus was similar to other plant viruses. The poliovirus was covered with more elaborate loops that are the site of monoclonal antibody escape mutations (Hogle, Chow and 229: 1358-1365Filman, Science). Individual proteins of the virus particle are produced by proteolytic cleavages from a larger precursor, yet the amino and carboxy-termini produced by proteolysis are very distinct. By noting this, Hogle and his team were able to conclude that proteolysis was not just making a lot of proteins from one gene, it is also controlling the timing of assembly (Hogle, Chow and Filman, Science 229: 1358-1365).