Polio Research Paper

2853 WordsOct 6, 201212 Pages
Ocean County College Department of Biology The Poliovirus Submitted By, Stephen Gorda Date Submitted: 5-2-12 Course: Biology- 162 Instructor: Prof. Estelle Abstract The poliovirus is one of the most transmittable and most contagious viruses that the human population has come in contact with. The structure of the poliovirus allows it to be able to bind to motor neuron cells within a host’s body and reproduce quickly. Like all virus’s, the poliovirus…show more content…
The similarity between the poliovirus and already solved plant virus’s led to a better understanding of how the poliovirus can regenerate within a host. Although the virus was similar to other plant viruses. The poliovirus was covered with more elaborate loops that are the site of monoclonal antibody escape mutations (Hogle, Chow and 229: 1358-1365Filman, Science). Individual proteins of the virus particle are produced by proteolytic cleavages from a larger precursor, yet the amino and carboxy-termini produced by proteolysis are very distinct. By noting this, Hogle and his team were able to conclude that proteolysis was not just making a lot of proteins from one gene, it is also controlling the timing of assembly (Hogle, Chow and Filman, Science 229: 1358-1365). B. Signs and Symptoms: Approximately 95 percent of people who are infected with poliovirus will not have any symptoms, however, people who are infected and do not have any polio indicators can still spread the poliovirus. People who become infected with the poliovirus can start having symptoms as soon as four days after being infected, and not have any symptoms for as many as thirty five days. This time period between infection and experiencing symptoms is referred to as “The Incubation Period,” which is when the virus begins to multiply within the cells that line the back of the throat, nose, and intestines(“Signs and symptoms of Polio.” eMedtv.com. Clinaero Inc., 2006-2012. Sunday 4-22-12). For the
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