Polio Virus Essay

We hear how Henrietta’s cells helped learn and find cures about so many viruses, but what is a virus? A virus is a microscopic organism that only replicates within the cells of a host organism. One of the most well known viruses Henrietta’s cells helped us with was the polio virus. Polio virus is a viral infection of your central nervous system. Polio virus is a lytic virus meaning that, polio goes through reproduction and the cells bursts. Polio virus’s most extensive outbreak was in the early to mid-1990s. Thankfully the vaccine was released in 1995.

Polio an American story is a scholarly readable and informative book which covers the lives of many American eminent scientists who struggled a lot to eradicate polio. This book mainly focuses on the mid twentieth century where the people are very eager to find a vaccine to eradicate polio .This book also covers the entire topics from appearance of polio symptoms to post polio syndrome which shows the valuable thesis done by David M. Oshinsky.

Nobody has ever discovered completely how it is that polio is spread. The best evidence suggests that the virus is excreted in the stool and passed through hand to hand or hand to mouth contact by people who do not wash their hands properly or often enough. It was during the first few years of the fifties and many years before then, that health department officials

Poliomyelitis (polio) is a disease that attacks the nervous tissue in the spinal cord and the brain stem resulting in paralysis (Document One). Polio is caused by the poliovirus, but it is unknown how this virus is acquired. The virus enters the digestive tract and stays in the intestines for up to eight weeks, and then attacks the lymphatic system, the blood stream and eventually travels to the brain and spine (Document Four). Once it is infected in one’s body, the disease is highly contagious and can be spread through contact of saliva, food, germs, or feces (Document Two). “The poliovirus causes most of its infections in the summer and fall. At one time, summer epidemics of polio were common and greatly feared” (Document Four). This may

With a substantial amount of preventive healthcare advancements behind them, the American medical community turned its attention to the deadly polio virus plaguing America. From 1937 to 1952, known cases of Americans contracting polio skyrocketed from ten thousand to a staggering figure of roughly fifty-seven thousand cases. Of those cases within that time period, approximately one thousand five hundred deaths as a result of polio were recorded. In the year 1953, The National Foundation for Infantile Paralysis provided the scientist Dr. Jonas Salk with the tools necessary to research, and develop a working vaccine to combat the devastating polio disease. After much trial and error, Dr. Salk was finally able to create what he felt was a successful polio vaccination, and proceeded to conduct a field test. After resounding success, manufacturing instructions for the Salk vaccine were sent to a series of scientific laboratories for immediate production and administration to American children. The disaster that occurred next will forever be known through American medical history as the Cutter Incident (named so after one of the labs that administered the polio vaccine). This medical crisis sent shockwaves throughout America and the medical community, and numerous lawsuits were filed against Cutter Laboratories, resulting in fewer and fewer labs willing to accept contract work in developing vaccines.

With the last outbreak of Polio in the US being in 1979, many today have no recollection of the terror of this disease. The disease primarily infected children, and there seemed to be no pattern to who succumbed to it. No one could feel safe. Polio as a disease presents such horrors that even those who overcome it once can be plagued by its aftereffects in later life. Before vaccines, single outbreaks could devastate entire communities. One outbreak

Once America’s most feared diseases and causing death and paralysis across the country, thanks to vaccination, there are no reports of polio in the United States.

Whens the last time someone developed Polio? Not in a long time, this is because we have developed vaccines to protect us. “Vaccines work by introducing diluted versions of viruses or bacteria into a person's body via injection” (Mandatory Vaccination). Since the discovery of vaccinations the medical world has changed forever. In today’s world many families have strong beliefs against vaccinations due to various myths and misconceptions. Since the discovery scientist have created vaccines for many illnesses around the world. When traveling abroad or anywhere to be precautious ask a doctor about vaccine protocols. This also would help prevent the spread of outbreaks. Everyone should be vaccinated because with everyone's immunity built up outbreaks

All three strands attack the nervous system and the digestive tract, making fecal matter and vomit infectious. Polio may also be contracted through contaminated food or water. Due to the highly infectious nature of the poliovirus, epidemics were rampant in poor communities and among young children attending school. Epidemics swept the nation during the 1930s, 20s and 10s. People lived in fear of their children contracting such a harmful illness. Schools and swimming pools were closed in order to prevent the spread of the virus (Last). Mothers were warned against breastfeeding, as the virus had the potential to be spread through breast milk

Polio, short for poliomyelitis, is a disease caused by the contraction of the poliovirus. Like influenza, smallpox and cholera, polio is a viral infection. This means that it is a disease caused by the spread of a virus. It spreads rapidly, and usually through person-to-person contact. In addition, this virus can also be distributed through foods or drinks contaminated by infected fecal matter. Although polio is deadly, sometimes, contractors of polio do not show any symptoms. The

The disease poliomyelitis is more commonly known by its alternative name “polio.” The history of this disease dates back into prehistory, but major polio epidemics were not known before the twentieth century. The first clinical description of this disease was provided by a British physician named Michael Underwood, in which he described the disease as debility of the lower extremities. In the 1880s major epidemics started to occur in Europe, then made its way soon after into the United States. The first report of multiple cases was recorded in 1843 and described an outbreak that happened in Louisiana in 1841. The next large outbreak was in Boston in 1893 where there were 26 cases of poliomyelitis. The following year was the first recognized epidemic in the United States which occurred in Vermont with 132 total cases, including 18 deaths. By 1907 there were approximately 2,500 cases of polio reported in New York City alone. By 1910, epidemics of polio were regular events throughout the developed world, mostly in cities during the warmer months. In 1916 there were over 27,000 cases including more than 6,000 deaths due to polio in the United States, with more than 2,000 deaths occurring in New York City alone. Poliomyelitis hit its peak in the 1940s and 1950s; it paralyzed or killed more than half a million people per year.

Poliomyelitis (polio) is an infectious disease caused by the polio virus and is spread from person to person through faecal-oral transmission which means; stool entering the mouth or consumption of food containing stool from an infection person. The poliovirus resides in the intestinal tract and mucus in the nose and throat. Contact with infected respiratory secretions or even saliva can cause poliovirus transmission. This mode of transmission is known as oral-oral transmission. Polio became prevalent in the United States of America (U.S) in the 1940s and 1950s.this was followed by outbreaks of the disease that crippled tens of thousands in North America. Polio eradication is aimed at reducing the global incidence of polio to zero through deliberate efforts to a point that it requires no further control. Polio eradication is to be achieved through interruption of endemic transmission of poliovirus through vaccination. This saw the wide use of the inactivated polio virus (IPV) that was administered orally (OPV); oral polio vaccine.

When hygienic conditions were poor polio attacked infants. The disease was spread by contaminated water and contact with fecal contamination. Many infants died when the conditions were poor. But as conditions improved the virus spread differently. It was spread more through playmates and family members, the contamination came from the

Polio is an infectious disease that has killed and paralyzed many people (Birth of Jonas Salk and the death of polio in India). It has taken the lives of

The similarity between the poliovirus and already solved plant virus’s led to a better understanding of how the poliovirus can regenerate within a host. Although the virus was similar to other plant viruses. The poliovirus was covered with more elaborate loops that are the site of monoclonal antibody escape mutations (Hogle, Chow and 229: 1358-1365Filman, Science). Individual proteins of the virus particle are produced by proteolytic cleavages from a larger precursor, yet the amino and carboxy-termini produced by proteolysis are very distinct. By noting this, Hogle and his team were able to conclude that proteolysis was not just making a lot of proteins from one gene, it is also controlling the timing of assembly (Hogle, Chow and Filman, Science 229: 1358-1365).