Introduction
Polycystic ovary syndrome (PCOS) is a condition that is estimated to effect between 6% and 10% of reproductive age women (Andreou, Barber, Dimitriadis, & Franks, 2016). In this paper we will define PCOS, examine the pathogenesis, identify ways to assess for the condition and review the treatment options on a mock patient.
PCOS Defined
There is still not a consensus among everyone on the medical community on the exact diagnosis criteria for PCOS, especially since criteria vary based on genetics and ethnicity. Since 2003 the Rotterdam European Society for Human Reproduction and Embryology and the American Society of Reproductive Medicine have agreed that PCOS can be diagnosed based on the following criteria:
1) All other conditions
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Nearly all of the recent research points out that there is a high comorbidity with PCOS, insulin resistance, and obesity. Obese women with insulin resistance are at the highest risk for developing PCOS. A 2015 research paper found that if conception is achieved (typically with the assistance of ovulation-inducing agents as we discussed) while the patient is diagnosed with PCOS the only notable increased health risk is GDM (Hayata, et al., 2015). However, a 2013 meta-analysis of 21 studies involving a combined 4,841 women with PCOS, and 1,196,705 control woman without PCOS found “women with PCOS demonstrated significantly elevated risk of gestational diabetes mellitus (3.5x), pregnancy-induced hypertension (3.4x), preeclampsia (2.2x), premature delivery (1.9x), caesarean section rate (1.7x), (and) admission to an NICU pregnancy (2.3x)” (Chen, et al., 2013) This research is supported by a recent article “Pregnancy Complications In Women With Polycystic Ovary Syndrome” which looked at this same meta-analysis as well as two other previous meta-analysis which came to similar conclusions. It is worth noting that in my research all of these complications with the exception of GDM, and pregnancy-induced hypertension can also be attributed to side effects of the fertility drug clomiphene citrate, especially if multiple eggs are fertilized. This statement is summed up well in the Pregnancy Complications article just mentioned: “infertility treatments are considered to be potential confounders in the evaluation of pregnancy complications” (Battista LaSala, et al., 2015). GDM is clearly the most common side effect that can be directly linked to PCOS therefore screening should be performed during the first trimester to allow for adequate insulin control which can typically be easily achieved with dietary modifications or insulin therapy such as
Polycystic ovarian syndrome (PCOS) is a heterogeneous collection of signs and symptoms that together for a spectrum disorder with a mild presentation in some but a severe in others. The pathophysiology of PCOS appears to be multifactorial and polygenic. (Fox, 2011)
Polycystic Ovary Syndrome is a hormonal disorder which effects around five million women of reproductive age in the United States (activebeat.co). The ovaries and adrenal glands excrete abnormally high levels of male hormones which prevents the regular release of an egg, causing many fluid filled sacs, or cysts, to form on the ovaries. Several types of cysts can be found on the ovaries of someone diagnosed with PCOS, the most common being those developed during the menstrual cycle, functional cysts. Follicular cysts are a subcategory of functional cysts formed by the overgrown follicle resulting from an unreleased egg. When a follicle ruptures following the release of an egg, the follicle may reseal and cause fluid buildup, resulting in a corpus luteum cyst; these cysts may enlarge considerably, causing pain, bleeding, or twisting of the ovary (PCOS Awareness Association). Some cysts resolve themselves in one to three months while others grow to be painfully large and require surgery to remove.
According to PubMed Health, Polycystic Ovary Syndrome (PCOS) is a condition in which women possess abnormally high level of male hormones. The high hormone levels lead to risks of irregular or absent menstrual cycles, insulin resistance, ovarian cysts, issues related to the circulatory system, obesity, heart disease, diabetes and etc. Symptoms differ between each woman therefore, despite research data collected showing that PCOS affects 5-10% of women between the age of 18-44, there are many women who live their lives unaware that they have PCOS. The most common symptoms include: absences of ovulation, high levels of androgen present, and abnormal hair growth. The cause of PCOS is still unknown as more research is much-needed to better understand the disorder.
The motive of this paper is to present a analysis of current research on polycystic ovary syndrome more commonly known as PCOS. Pcos is one the most common endocrine disorders in women of reproductive age, affecting 5-10% of the population. Despite it's prevalence, pcos remains largely unknown. The main focus of this paper will be explaining what PCOS is, the causes, the diagnosis and the treatment of polycystic ovary syndrome.
The authors also found that PCOS can cause many long term side effects, including Type II diabetes, cardiovascular disease, mood disorders, and malignancy. Type II diabetes is due to the high prevalence of obesity leading to insulin resistance in PCOS. Women with PCOS are at higher risks for cardiovascular diseases including increased levels of low density lipoproteins. Polycystic ovary syndrome can also lead to anxiety, depression and binge-eating. Women with obesity have a
Since PCOS is the most common endocrine disorder for women of reproductive ages, Questions to explore are: How does lifestyle factors such as obesity impacts the development of PCOS, how does PCOS affects a women quality of life and what are the best treatment options?
If the pancreas can manage with your body’s high demand for insulin your blood sugar levels will remain normal and you would not become a diabetic. Because diabetes and PCOS is closely related it is monitored closely. It is shown that women with PCOS is in much greater risk in developing diabetes. Research has shown that once the pancreatic islet cells have become exhausted and depleted in the over production of insulin to satisfy the body requirements, your pancreas stop making insulin and your blood sugar becomes elevated. When that happens the patient becomes diabetic. Besides diabetes a woman with PCOS is more likely to develop uterine cancer and heart disease. Patients are also advised not to smoke while diagnosed with PCOS because it increases the risk for heart disease.
Imagine a syndrome that can cause you, or a woman you know, to be infertile, depressed, anxious, obese, or hirsute, along with many others. Polycystic ovary syndrome can cause all of these issues in a woman who is affected by the condition. If it is not treated properly or on time, it could lead to other serious medical issues that could even be life threatening. Polycystic ovary syndrome, otherwise known as PCOS, is not a commonly known syndrome and many women affected by it are not diagnosed or treated for it. PCOS is a major medical problem that is affecting five to ten percent of the female population in the U.S. and many more across the globe (American Diabetes Association, 2014). This syndrome must become better known in the near future so that women with PCOS can take better control and care of their own body.
About 5-10% of the female population is affected by Polycystic Ovary Syndrome (PCOS). The cause is unknown, but it is considered to be the most common endocrine disorder in women. Genetics and insulin resistance are believed to play a significant role. One of the first symptoms is an irregular period. Others include an imbalance in the female sex hormones, weight gain, and male-patterned hair growth and balding. Aside from hormonal treatments, there are some natural ways to treat PCOS and eliminate many of the symptoms. A proper diet and weight loss routine is essential. After my own horrific experience with PCOS, I decided to take my health into my own hands. At the beginning of the month, I weighed 320 lbs. My goal is to get down to 180 lbs. by April 13th, 2014. Today is Day 13 of my lifestyle change and my current weight is 301.2 lbs. Here are some helpful things I 've learned so far: Keep a Weight Loss Journal So many of the weight loss tips I 'd read talked about keeping some sort of journal to keep track of progress, calories, and the weight lost. I registered at MyNetDiary and began using that immediately. I chose MyNetDiary because it also featured an application for my smartphone, making it accessible on the go. Try to Plan Your Meals Ahead of Time With MyNetDiary, your meal can be planned beforehand. I find it works best if you start getting an idea the night before about what your meal plan is going to look like the next day. If you have a vague idea, you
The condition Polycystic ovary syndrome(PCOS) is the most common of endocrine disruptions within women of reproductive ages. The disorder does affect as much as 10% of women within this reproductive lifecycle. The clinical and biochemical features of the condition are diverse and are as follows: fertility disruption, overweight/obesity, irregularities in menstruation (frequent, absent, sporadic) insulin resistance/type 2 diabetes, and increased risk of cardiovascular disease (Jeanes &Hart &Smith & Barr, 2009). The exact aetiology of Polycystic ovary syndrome (PCOS) is unknown but does involve both environmental influencers and genetic factors. In summery Polycystic ovary syndrome (PCOS) is a common endocrine condition associated with metabolic dysfunction, infertility, and hyperandrogenism. Treatment for PCOS includes diet and lifestyle changes in order to promote a healthy body mass index (BMI) and further reduce hyperinsulinaemia (a symptom of the condition). Medications such as metformin/Glucophage might be utilized for management of the presenting symptoms. PCOS symptoms at present-day can only be managed and no cure for Polycystic ovary syndrome available. (Jeanes &Hart &Smith & Barr, 2009).
Greece, one of the most beneficial countries of the world, has come up with many inventions that are still used today. Tragically, many of these concepts were lost when the Romans burned the Library of Alexandria, but there were copies of some of the information. Still, much of this valuable information was lost pushing back humanity. Not only have the Greeks fathom great ideas, they have also influenced other cultures. An of this is the America government buildings.
Your health is your wealth. When you look good, you'll naturally feel even better. Poly-cystic Ovarian Syndrome (PCOS) affects the looks and overall health of countless women. The common symptoms of women with PCOS include weight gain, acne, depression/moodiness and hirsutism. There are other symptoms that can flare up, but all of these issues can run a number on a woman's self-esteem and appearance. Additionally, there's no cure for PCOS. Most times, doctors prescribe medicines like Metformin to manage the insulin resistance issue. Many women deal with this and feel alone and hopeless. Thankfully, there is a way to manage the symptoms and experience the appearance and body of your dreams. The solution revolves around lifestyle changes. The changes can be
Polycystic ovary syndrome (PCOS) affects approximately seven to eight percent of women of childbearing age. While the cause of PCOS is still unknown, it is believed to be a genetic disorder. Often a mother or sister of a woman affected will exhibit symptoms similar to PCOS. Due to the change in the levels of estrogen and progesterone, during ovulation mature eggs are not released which begin to form very small cyst within or on the ovary. These cysts cause infertility. Women suffering from polycystic ovary syndrome can overcome infertility through weight loss, laparoscopy (ovarian drilling), medicinal treatment or in vitro fertilization (IVF).
There are many long-term consequences of PCOS. If PCOS is not properly treated there is a bigger chance of having long-term consequences. One of these consequences is type II diabetes. Women with PCOS frequently have hyperinsulinism and insulin resistance. Women who have irregular ovulation tend to have more insulin resistance. Insulin resistance is a precursor to diabetes, so PCOS patients are more at risk of developing diabetes. It is also shown that women with PCOS are more at risk of having glucose intolerance. Researchers found that women with PCOS also have an increased incidence of mortality related to diabetes complications (Nandi et al., 2014).
In the Early Modern Period places such as Russia, the Ottoman Empire, China, and the Mughal Empire all underwent changes within their own culture. Even though these places went through economic, territorial, and agriculture changes only Russia decides to adopt a Westernize philosophy for their country.