Portal Cholangiopathy

When gallstones are suspected to be the cause of symptoms, the doctor is likely to do an ultrasound exam or CT Scan, the most sensitive and specific test for gallstones. Other exams that may be performed are a Cholescintigraphy a.k.a. HIDA (hepatobiliary iminodiactec acid) Scan, ERCP (endoscopic retrograde cholangiopancreatography), and blood tests.

One of these symptoms is jaundice, which is characterized by yellowish skin and eyes because of an inability of the liver to remove bilirubin from the blood. Patient with cirrhosis also suffering from itching, due to deposited bile's products in the skin. This patient also suffers from accumulation of fluid in legs that is called edema. As a result of the blockage of blood flow via the liver, fluid accumulation in abdomen which is worsen by the decrease in protein production. Other symptoms include fatigue, weakness, loss of appetite, weight loss and nausea. As the disease progress, complications may develop ,such as varices that happens with cirrhosis patient when the blood flow through the liver slows, so the blood from intestine go back to the vessels of the stomach and esophagus, these vessels are not meant to carry this much of blood so they dilate (varices), with increasing

I knew the severe symptoms that I had were not characteristic of gallbladder disease. Particularly not in the beginning, when there was only a very small amount of gallbladder sludge. The very elevated liver enzymes I had were also a mystery because they also do not occur when there is gallbladder sludge alone. They can occur when there is sludge blocking a duct, but there never appeared to be any obstructed ducts in either of the ultrasounds I had during that

Diagnosis of Obstetric Cholestasis is made by excluding all other liver diseases. Blood test to assess OC should generally include Liver Function tests as well as screening for Hepatitis B and C and Serum bile acids. (Bryne, 2000). Kenyon et al 2001 suggest that bile acid levels will often rise before liver function tests become abnormal so continual investigation is vital. Jacinta presented with intense pruritus however her liver function tests and serum bile levels were initially normal. Many women will have pruritus for days or weeks before the development of any abnormal liver function (Kenyon et al 2001). Midwives need to be extremely vigilant and not ignore persistent pruritus even in the presence of normal blood results. Diagnosis is suggested if a woman in the third trimester of pregnancy develops pruritus without a rash and at least one biochemical liver abnormality (See appendix) (Walker, Nelson –Piercy and Williamson, 2002). However OC has been diagnosed in women at only eight weeks gestation, (Mays 2010) and Jacinta presented to her General Practitioner with pruritus at twenty four weeks. Diagnosis can be extremely

Decompensated cirrhosis is characterized by the development of a cirrhosis-related complication, including variceal hemorrhage, ascites, spontaneous bacterial peritonitis, hepatorenal syndrome, and/or coagulopathies. For patients with compensated and decompensated cirrhosis, the risk of death is 4.7 and 9.7 times higher than the general population, respectively.4 Survival in patients with decompensated cirrhosis is considerably lower than that of patients with compensated cirrhosis. The median survival times are as low as 2 years in decompensated patients and greater than 12 years in compensated

The liver produces bile which contains conjugated bilirubin. It is then sent to the gallbladder, and it has to be excreted properly from there. However, the gallstones are blocking the way, which makes it hard for the bilirubin to get out, and results in a build-up. This leads to jaundice, which occurs when one has and excessive amount of bilirubin.

In the presented case scenario, we have Mr. Gil Martin who is a 55-year-old Hispanic male. He comes in to the clinic today with complaints of weakness, fatigue, and loss of appetite. A student nurse will be precepting your assessment of Mr. Martin and when collecting subjective and objective data it is important to pay close detail to all findings. Ultimately this patient was diagnosis with cirrhosis, which is an abnormal liver condition that leads to irreversible scarring of the liver (National Institute of Health [NIH], 2017), so during assessment we should pay attention to details leading to this diagnosis.

Abdomen: Soft, non-distended, non-tender throughout with palpation. No guarding or rebound. No masses. No hepatomegaly, spleen is non-tender with palpation. No aortic, renal, iliac, or femoral bruits auscultated, no friction rubs heard over the liver or spleen. Active bowel sounds in all 4 quadrants.

I. Introduction: It is estimated that approxiamately 10 to 20 percent of the population in the United States and Western Europe are currently being affected by Gallbladder attacks.

Wilson disease has a range of clinical manifestations, from an asymptomatic state to fulminant hepatic failure, chronic liver disease with or without cirrhosis, neurologic, and psychiatric manifestations. Often, the diagnosis is not made until adulthood, despite manifestations of the disease beginning to develop in childhood. Hepatic Wilson disease should be considered in the differential diagnosis of any unexplained chronic liver disease, especially in individuals younger than 40 years. The condition may also manifest as acute hepatitis. Hepatic dysfunction is the presenting feature in more than half of patients. The 3 major patterns of hepatic involvement are as follows: (1) chronic active hepatitis, (2) cirrhosis, and (3) fulminant hepatic failure. The most common initial presentation is

Experts claim that the consumption of the mixture within the morning, on an empty abdomen, prevents the expansion of gallstones. Moreover, the consumption of a glass of water, olive oil, and juice an hour before the breakfast will detoxify the liver, kidneys, and the

Biliary colic is caused by a blockage in the bile duct. The bile duct is a pathway that carries bile, a liquid that helps to digest fats, from the gallbladder to the small intestines. Biliary colic usually occurs after eating, when the digestive system demands

It is widely agreed upon in medicine that time is of the essence when it comes to diagnosis and treatment of disease. The pediatric disease, biliary atresia (BA) is no different in this regard, as it has been well accepted for several decades that the timely recognition and repair of BA is essential1. BA is a progressive, idiopathic disease characterized by extensive fibrosis of the extrahepatic biliary tree resulting in blockage of bile flow. BA is the most common cause of surgically correctable jaundice. It may also clinically manifest as scleral icterus, acholic stools, and urobilinogen; eventually leading to cirrhosis and hepatic failure if the disease is left untreated. BA is often fatal before the age of one year old if left untreated and as a result has become the most common indication for liver transplant in children1,2. The hypothesized pathogenesis of BA includes viral, immunologic, and genetic etiologies but currently no definitive cause for BA is known. The gold standard in diagnosing BA is intraoperative cholangiogram, which allows for direct progression to surgical correction of the anomaly if characteristic findings of BA are seen. The most common surgery performed in patients with BA is the Kasai Portoenterostomy (KP); which is intended to restore bile flow to the liver and proximal small bowel3,4. An early indication of a successful KP is resolution of jaundice demonstrating return of bile flow; the earlier in infancy this occurs the better the

The gallbladder stores and concentrates bile. If the gallbladder was damaged or dysfunctional there would be softer and more frequent stools. (Audesirk, T., & Audesirk, G. (1999). Retrieved November 21, 2015 from Chapter 29: Nutrition and Digestion. In Biology: Life on Earth (5th ed., p. 585, 586). Upper Saddle River, N.J.: Prentice Hall.) (General Surgery- Gallstones (Cholelithiasis). (n.d.). Retrieved November 21, 2015, from

Acute cholecystitis is the acute inflammation of the gall bladder, which is most commonly caused by gall stones [1]. Gall stones affect about 10% of the western population [2]. Asymptomatic gall stones are present in more than 80% of the patients and among the patients of symptomatic gall stones only 1-3% develop acute cholecystitis [1], [3]. Hence acute cholecystitis is considered the most common severe complication of gall stones [3]. Ascariasis- a major cause of biliary disease also results in acute cholecystitis b/c the cystic duct obstruction caused by the helminth causes an inflammatory process to start [4]. Acute cholecystitis is diagnosed on the basis of clinical features and ultrasonography [1]. Literature gives two opinions regarding the surgical treatment of acute cholecystitis- first is the early surgery within few days