Post Antibiotic Era

Antibiotics have played an essential role in the fight against diseases and infections since the 1940’s. Antibiotics are a leading cause for the rise of global average life expectancy in the 20th and 21st century. They have greatly reduced illnesses and deaths due to diseases. With the introductions of antibiotics in the 1940’s, like penicillin into clinical practice, formally deadly illnesses became immediately curable and saved thousands of lives (Yim 2006). Antibiotic use has been beneficial and when prescribed and taken correctly their effects on patients are exceedingly valuable. However, because these drugs have been used so widely and for such a long period of time the bacteria that the antibiotics are designed to kill have adapted,

In the last decade, the number of prescriptions for antibiotics has increases. Even though, antibiotics are helpful, an excess amount of antibiotics can be dangerous. Quite often antibiotics are wrongly prescribed to cure viruses when they are meant to target bacteria. Antibiotics are a type of medicine that is prone to kill microorganisms, or bacteria. By examining the PBS documentary Hunting the Nightmare Bacteria and the article “U.S. government taps GlaxoSmithKline for New Antibiotics” by Ben Hirschler as well as a few other articles can help depict the problem that is of doctors prescribing antibiotics wrongly or excessively, which can led to becoming harmful to the body.

Widespread use of antibiotics has been very controversial in the media as well in the general population. Due to these controversies, it is very misunderstood to how antibiotics work leading to many patients in the hospital setting wanting to take them when it is not necessary or refusing to take when it is necessary for their survival. Some of this controversy is due to antibiotic resistance, which has spread an alarming rate in the 21st century (Walsh, 2000). Antibiotic resistance is the result of very strong bacteria or microbes that are resistant to the antibiotic prescribed and those microbes accumulate overtime by their survival, reproduction and transfer, leading to increased levels of antibiotic resistance.

Antibiotic Resistance Nicholas J. Ciotti Nova Southeastern University Biology 1510 Professor A. Hirons March 28, 2011 Abstract Antibiotic resistance is when microorganisms, such as bacteria, are able to survive an exposure to antibiotics and these bacteria are now resistant to the effects of these antibiotics. Antibiotic resistance in bacteria has been an issue since antibiotics were discovered. The fact that bacteria can become resistant to our medical treatments such as antibiotics is a natural evolutionary process, but there are certain human contributions that definitely speed up the process. For example, one of the main contributions that will be discussed is the problem of over prescription of the antibiotic drugs. The

Antibiotic Resistance: Where we are and what we need to do Oluwatosin Fofah Antibiotics are inarguably one of the greatest advances in medical science of the past century. Although the first natural antibiotic Penicillin was not discovered until 1928 by Scottish biologist Alexander Flemming, evidence exists that certain plant and mold growths were used to treat infections in ancient Egypt, ancient India, and classical Greece (Forrest, 1982). In our modern world with the advent of synthetic chemistry synthetic antibiotics like Erithromycin and its derivative Azithromycin have been developed. Antibiotics have many uses including the treatment of bacterial and protozoan infection, in surgical operations and prophylactically to prevent the development of an infection. Through these applications, antibiotics have saved countless lives across the world and radically altered the field of medicine. Though a wonderful and potentially lifesaving tool, antibiotic use is not without its disadvantages. Mankind has perhaps been too lax in regulation and too liberal in application of antibiotics and growing antibiotic resistance is the price we must now pay. A recent study showed that perhaps 70% of bacterial infections acquired during hospital visits in the United States are resistant to at least one class of antibiotic (Leeb, 2004). Bacteria are not helpless and their genetic capabilities have allowed them to take advantage of society’s overuse of antibiotics, allowing them to develop

Since the introduction of penicillin to the public in 1942, antibiotics have gained widespread use throughout the world. The drug has allowed society to make advancements in medicine, increase an individual’s personal well-being, extend life expectancies, and stop

Antibiotics differ from many other drugs in the fact that the treatment is for a very short time compared to drugs used to treat hypertension, diabetes, Parkinson’s, or cancer. The latter disorders have in common that the treatment, from the moment of diagnosis, is life-long. The treatment period for antibiotics is only a few weeks, making the return of investment poor. Increasing demands of authorities in both development and marketing phase and in legislation increase the costs of new antibiotics.[1] [3]

Antibiotic resistance evolves in bacteria. Charles Darwin created the theory of evolution which focused on natural selection being the key factor of how things change. Natural selection is when organisms that are better suited to the environment are able to reproduce successfully. Evolution is descent with modification. Bacteria can become resistant to antibiotics by a mutation. The bacteria that did not die from the antibiotic inherited the gene from an ancestor that made it resistant. Since the other bacteria is dying faster than the resistant bacteria, the resistant bacteria are able to multiply

A current predicament in the field of science is antibiotic resistance against superbugs.Though fighting against superbugs; which can be defined as a strain of bacteria unable to be killed using multiple antibiotics, is now a large problem, in the past it was not. The evolution of resistance in bacteria due to antibiotic abuse and lack of product development has brought upon us once again the fear of a pre-antibiotic era; one where simple, once easily defeated infections could kill. Already, infectious diseases are the 3rd leading cause of death in the US and the 2nd across the entire world, and drug resistant superbugs send 2 million Americans to hospitals every year; killing 23,000 of those people. And any bacterium can quickly and easily become multidrug resistant, the leading cause of this being antibiotic misuse in both humans and animals.( "Clinical Infectious Diseases." The Epidemic of Antibiotic-Resistant Infections: A Call to Action for the Medical Community from the Infectious Diseases Society of America. UCLA Medical School. Web. 27 Mar. 2016.)

In the last fifty years, the most prominent and transformative medical advancement made was the discovery of antibiotics and disinfectants. On the contrary, with the uncovering of antibiotics came the repercussion of the progressively threatening antibiotic-resistant bacteria. Antibiotic-resistant bacteria or ‘superbugs’ formed due to the lack of care from the people to follow through with simple safety procedures in order to entirely get rid of bacterial illnesses and infections. Appropriate precautions are necessary and expectedly need to be taken, in order to minimize and possibly prohibit the formation, continual growth and limit the strength of resistance in the antibiotic-resistant superbugs, and most importantly to preserve medical advancements

The original success of antimicrobial agents has had a large influence over America’s dependency of antibiotics. Originally, these agents were widely considered as a cure-all drug by many involved in the health field and by the Americans receiving these medications. Such medical breakthrough won alexander Fleming, the creator of penicillin, a Nobel Prize in 1945 (“Antimicrobial Resistance: Global Report”) Regardless of the beneficial properties his vaccination, he warns that improper use can be followed by great consequences. Today that holds to be very true. For a period of time, there was a rapid rise in the production of different antibiotics to meet the supply and demand of health care prescriptions and patient consumption. Over time,

The general populace of western civilization may believe that modern medicine is limitless and that numerous afflictions that are common can be easily resolved with the major strides medicine has taken in the past century. In the case of antibiotics, this couldn’t be farther from the truth and its use leaves a nasty prospect for the future. Antibiotics, the type of drug that is capable of killing harmful bacteria, is widely regarded as a simple gift from medical research and is expected to be prescribed for even the mildest of illnesses. However, the use of antibiotics has proved that it comes with a terrible byproduct: leftover bacteria that survives the drug and evolves strains that are resistant to the drugs the world currently

History of Antibiotic Resistance In the past tense 60 years, antibiotic drugs have been critical to the fight against infectious disease caused by bacteria and other microbe. Antimicrobial chemotherapy has been a lead cause for the dramatic rise of norm life expectancy in the Twentieth Century. 1 However, disease-causing bug that have become resistant to antibiotic drug therapy are an increasing public health trouble. “Wound contagion, tuberculosis, pneumonia, gonorrhea, childhood ear infections, and septicemia are just a few of the diseases that have become hard to treat with antibiotics.” 2 One part of the job is that bacteria and other germ that cause infections are remarkably resilient and have developed several ways to resist antibiotics and other antimicrobial drug. 3 Another part of the problem is due to increasing use, and abuse, of existing

The overuse of antibiotics has been a problem for well over a decade. This misuse leads to many nonvisible problems arising within the human population. As the use of antibiotics increases, the number of antibiotic resistant bacteria also increases. When bacteria become resistant to an antibiotic, another antibiotic must be

According the World Health Organization (WHO), antibiotic resistance is one of the world’s greatest health threats to date (Haddox, 2013). In the article, The Health Threat of Antibiotic Resistance, Gail Haddox (2013) discusses the danger antibiotic resistance poses in today’s society and strategies to prevent the expansion of antibiotic resistance. In Europe alone, an estimated 25,000 deaths have been attributed to multi-resistant infections (Haddox, 2013). Common infections are now harder to treat due to the increased resistance to antibiotics across the world, in fact some are becoming untreatable. Antibiotics should be treated like oil, a non-renewable resource (Haddox, 2013).