Comparison of the effectiveness of different classes of antidepressants with placebo and with other forms of treatment like psychosocial interventions in women with postpartum depression
Introduction
.Depression is one of the psychological disorders that influence 15-25 % of adults in United States every year. Women are twice as likely as men to experience symptoms of depression. In women, most common period of occurrence of depression is between 18-44 years and this happens to be the prime childbearing years. Women who are at risk for depression are very vulnerable during pregnancy and after child birth because of hormonal fluctuations. Postpartum depression is a clinical term associated with a major depressive episode associated with childbirth.
…show more content…
This can affect the confidence of the new mother in caring for her new baby. Post partum depression is seen in 80% of women who gives birth but in most women the symptoms resolve within 2 weeks. If the symptoms last longer than that, it is recommended that she should be screened for Post partum depression. Studies have shown that children of mothers with postpartum depression displays problems with social emotional and cognitive development and these changes are visible in children as young as 3 months old. Early detection and treatment of postpartum partum depression is crucial to the physical and emotional well being of the mother and baby .It is important to know the signs and symptoms of the condition and intervene appropriately. Antidepressants are commonly used as the first treatment option for adults with moderate to severe depression, but there is little evidence on whether antidepressants are an effective and safe choice for the treatment of this disorder during this period. Serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs) are …show more content…
This might have affected the generalisability of the study. The dose of Sertraline was titrated very slowly over this 6 week period and the study was not long enough to demonstrate a group- time effect and this may have limited the ability to detect an impact of treatment with an active drug before study
Postpartum depression is one of the most common complications of childbearing with an estimated prevalence of 19.2% in the first three months after delivery (1). Depressive episodes (major and mild) may be experienced by approximately half of women during the first postpartum year (1). Characterized by depressed mood, loss of pleasure or interest in daily activities, feelings of worthlessness and guilt, irritability, sleep and eating disturbances (2), its etiology is multi-faceted and complex (3;4).
may be linked to medications used during pregnancy. It is speculated that there are a multitude of health risks to the fetus if an expecting mother is prescribed antidepressants for Major Depressive Disorders. It is also hypothesized that there may be long-term effects to the child after birth if the mother of the child was taking antidepressants during her pregnancy. Postnatal psychological effects may be due to the onset of the drugs during pregnancy, and there may be a link between a child’s physical and psychological state once born, due to the drugs, but is not correlated to women that have used antidepressants before pregnancy. Results identify that there are many negative effects of antidepressants use during pregnancy.
Often the time after birth is a filled with joy and happiness due to the arrival of a new baby. However, for some mothers the birth of a baby leads to some complicated feelings that are unexpected. Up to 85% of postpartum woman experience a mild depression called “baby blues” (Lowdermilk, Perry, Cashion, & Alden, 2012). Though baby blues is hard on these mothers, another form of depression, postpartum depression, can be even more debilitating to postpartum woman. Postpartum depression affects about 15% (Lowdermilk et al., 2012) of postpartum woman. This disorder is not only distressing to the mother but to the whole family unit. This is why it is important for the nurse to not only recognize the signs and symptoms of a mother with postpartum depression, but also hopefully provide preventative care for the benefit of everyone involved.
This journal article focuses on postpartum depression and how it differentiates from other disorders. This paticuarl article however focuses on defining the different types of depression within this catagorey and looks into clinical involvement as well as recognsisng risk elements and sysmtoms that allow it to be characterized from other mood and anxiety disorders. Beck (2006) finds that persons who where most at risk of this disorder most commently had stressful lives, with a history of mental illness. This article also concludes that postpartum depression can lead into server physosi, which is in need of immediate intervention and that this mental state can lead women to be dangerous to themselves of there children and clearly states that they should never be left alone. Overall this article is paticually usuful as a researcher as it clearly describes the differences in distinguishing the types of depression as well as the servierty of postpartum depression which can be underrecognsied.
Postpartum psychiatric disorders, particularly depression, has become the most underdiagnosed complication in the United States. It can lead to increased costs of medical care, inappropriate medical care, child abuse and neglect, discontinuation of breastfeeding, and family dysfunction and adversely affects early brain development (Earls, 2010). Over 400,000 infants are born to mothers that are depressed. One of 7 new mothers (14.5%) experience depressive episodes that impair maternal role function. An episode of major or minor depression that occurs during pregnancy or the first 12 months after birth is called perinatal or postpartum depression (Wisner, Chambers & Sit, 2006). Mothers with postpartum depression experience feelings of extreme sadness, anxiety, and exhaustion that may make it difficult for them to complete daily care activities for themselves or for others (Postpartum Depression). The six stages of postpartum are denial, anger, bargaining, depression, acceptance and PTSD. These stages may affect any women regardless of age, race, ethnicity, or economic status. However only a physician can diagnose a woman with postpartum depression. It does not occur because of something a mother does or does not do, it’s a combination of physical and emotional factors. After childbirth, the levels of hormones in a woman’s body quickly drop; which may lead to chemical changes in her brain (Postpartum Depression). Unbalanced hormones may trigger mood swings.
Postpartum depression, which is the most prevalent of all maternal depressive disorders, is said to be the hidden epidemic of the 21st century. (1) Despite its high prevalence rate of 10-15% and increased incidence, postpartum depression often goes undetected, and thus untreated. (2) Nearly 50% of postpartum depression cases are untreated. As a result, these cases are put at a high risk of being exposed to the severe and progressive nature of their depressive disorder. (3) In other words, the health conditions of untreated postpartum depression cases worsen and progress to one of their utmost stages, and they are: postpartum obsessive compulsive disorder, postpartum panic disorder, postpartum post traumatic stress, and postpartum psychosis.
Postpartum depression (PPD) affects at least 10-20% of new mothers. However, the true incidence may be much higher due to the fact that screening is not considered to be a standard practice, leaving PPD undetected and untreated in many women (Schaar & Hall, 2014). Postpartum depression not only negatively affects the mother; it also has a negative impact on the infant. For this reason, it is important for the health care providers caring for pregnant and postpartum mothers to screen them for risk factors associated with PPD, as well as educate them on ways to lessen their chances of getting PPD. It is also important for the health care providers to screen for PPD with a standardized tool like the Edinburgh Postnatal Depression Scale (EPDS), and to take action in treating it when it is suspected or diagnosed.
The Center for Disease Control estimates that 1 in 20 people suffer from depression (2014). Although widely recognized and somewhat easy to diagnose, depression is an ignored and almost hidden, disease. In women, the statistics are especially grim for those who are pregnant or were recently pregnant. A great number of women suffer from postpartum depression; an illness which is often overlooked, misdiagnosed and untreated. Postpartum depression (PPD) has been defined as an emotional disorder that occurs in an estimated 10-15% of all women after childbirth (Liberto, 2010). Postpartum depression not only impacts the mother, but can cause long-term psychological challenges for the baby and create emotional turmoil for all family members.
You can find better ways to cope with your feelings, solve problems, and set realistic goals. When you take antidepressants your doctor may recommend that the only medication you take during this time. Another treatment used for postpartum depression would be Electroconvulsive therapy. According to staff “If your postpartum depression is severe and does not respond to medication, ECT may be recommended. During ECT, a small amount of electrical current is applied to your brain to produce brain waves similar to those that occur during a seizure. The chemical changes triggered by the electrical currents can reduce the symptoms of psychosis and depression, especially when other treatments have failed. ”If your postpartum depression is severe and does not respond to medication, ECT may be recommended. During ECT, a small amount of electrical current is applied to your brain to produce brain waves similar to those that occur during a seizure. The chemical changes triggered by the electrical currents can reduce the symptoms of psychosis and depression, especially when other treatments have
Postpartum depression in a common experience for newer mothers to have after childbirth. It is meant to last only a few days but can extend for a few months if it is severe. It is thought that it is caused by extreme hormonal shifts in the body after childbirth. If not treated in time, it has a potential chance harm the mother or the child. It is important that the mother feels appreciated and respected during this time. This article will help by giving further information in postpartum depression and further help the claims of how gender roles can further depression.
Depression is an illness and it is very common. National survey data showed that about one 1 out of 10 women 18-44 year’s old experienced symptoms of major depression in the past year (Depression, 2017). Examiners explain that depression does not feel the same for everyone according to how often the symptoms occur, how long they last, and how intense they may feel can be different for each person (Depression, 2017).
The current methods of treatment for postpartum depression include antidepressant medication, such as selective serotonin reuptake inhibitors (SSRIs), selective norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants, and/or psychotherapy. However, there is a certain amount of risk when taken during pregnancy and lactation. These medications are a pregnancy category C and SSRIs, have been shown to have a slight risk of heart and lung birth defects (Reefhuis, Devine, Friedman, Louik, & Honein, 2015). In breastfeeding mothers, all psychiatric medications are secreted in breastmilk, and some
Consequently, the treatment for postpartum depression is more intense than that for the baby blues. Among the many treatments, many mothers undergo intense counseling, take antidepressants, or even experience hormone therapy ((3)).
Depression is more common in women than in men across all age groups and cultural backgrounds with a female to male ratio of 1.68 (Kessler et al. 1993). Women are at their greatest risk of suffering from depression during the childbearing years. Currently, up to 20% of the pregnant women population are prescribed an antidepressant during pregnancy (Pawluski JL), and others may become pregnant while on one. According to Mourilhe and Stokes (1998), only one in 20 depressed patients are diagnosed and adequately treated. Selective serotonin reuptake inhibitor (SSRI) medications are the most common antidepressant treatment used during pregnancy and the postpartum period (Pawluski JL). It is important to treat depression in an expecting mother as studies show a negative effect of depression on pregnancy outcomes (Steer et al. 1992), maternal infant bonding (Condon and Corkindale 1997), cognitive development in children (Cogill et al. 1986), and subsequent recurrences of depression, resulting in problems for the child (Philipps and O’Hara, 1991). Because of the potential for maternal depression in pregnancy to cause negative impacts on both the mother and offspring, treatment (for the depression?) is highly recommended (Morrison, Riggs, & Rurak 2005). As such, fluoxetine is a frequently prescribed SSRI to pregnant women [need?] as it increases serotonin neurotransmission and has fewer side effects compared to other antidepressants (Morrison JL1, Riggs KW, Rurak DW).
According to a Mental Health America survey on public attitudes and beliefs about clinical depression and women’s attitude toward depression: More than one-half of women believe it is normal for a woman to be depressed after giving birth ,during menopause and is part of aging. Therefore seeking treatment is not necessary and denial to the fact plays an important role.