Pregnancy Institutes A State Of Insulin Resistance And Hyperinsulinemia Essay

Cortisol plays a major role in the development of this disorder. It is secreted by the adrenal gland, located above the kidneys, in a precise sequence of events. The hypothalamus directs corticotropin-releasing hormone(CRH) to the pituitary gland.1 CRH causes the pituitary to release adrenocorticotropin hormone(ACTH) activate the adrenal glands.1 The adrenal glands pick up the ACTH, they reciprocate by releasing cortisol in the bloodstream.1 Cortisol helps with quite a few of your body functions. Some of these functions are stress response, balancing the effects of insulin, reducing the immune system’s inflammatory response, regulating

During a pregnancy these increased hormones are made by the placenta, which is helping move nutrients from the mother to the baby, and also making hormones to prevent the mother from developing low blood sugar by stopping the actions of insulin (Seibel, 2009).” A pregnant woman’s pancreas is usually able to produce more insulin to overcome the effect of the pregnancy hormones; however, if for some reason a women’s pancreas cannot make up the difference the blood sugar levels will rise and gestational diabetes will occur.(Seibel, 2009)

The clinic RN reviews Amanda's prenatal record prior to performing a nursing assessment. Amanda has given birth twice, once at 35-weeks (twins) and once at 39-weeks (singleton). All of these children are alive and well. She has had one spontaneous abortion at 9-weeks gestation.

It is estimated that 387 million people, globally live with diabetes (Phillips & Mehl, 2015). According to Medical News Today [MNT], diabetes is a metabolic disorder; which causes patients to be extremely thirsty and produce a lot of urine. Diabetes arises due to high blood pressure, due to the body not being able to produce enough insulin or because the body does not respond well to high insulin levels (MNT, 2016). There are four types of diabetes; there is the pre-diabetic stage, type 1 diabetes, type 2 diabetes and gestational diabetes. In 2014, 29 million people died due to diabetes. This equates to 1 diabetic patient dying every seven seconds due to preventable complications (including complications affecting lower limbs) caused by diabetes. It is said that 20-40% of health care costs are spent on the treatment of lower limb complications due to diabetes. The risk of a diabetic patient developing a foot ulcer is 25% and foot ulcers account approximately 85% of lower limb amputations. Diabetic complications that affect lower limbs are caused by both type 1 and type 2 diabetes (Phillips & Mehl, 2015). It is said that the World Health Organization described diabetic foot syndrome as including all possible complications in relation to the feet of a diabetic patient. Diabetic foot syndrome is defined as the ulceration of the foot, from the ankle downwards. Causes of foot ulceration include peripheral sensory neuropathy, vascular disease (ischaemia) and infection

As the years go by, society starts to progress and develop many fast and easy solutions for everything. Not only are the easy solutions being created but the cost of living is increasing making people to work harder and later and not have time to have a healthy lifestyle. Fast foods are everywhere you go and not only is it fast it is also cheap making it harder to get a decent healthy meal. Due to society changing so much, diabetes is on the rise. What is diabetes? Diabetes is several diseases that are characterized by high levels of glucose that are the results of the insulin action or production. “The term diabetes mellitus describes a metabolic disorder of multiple aetiology characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.” (CDC) If diabetes is not taken seriously, it can have severe damages that include organ failures or damages and even death.

The prenatal period is when quick changes in the fetal organs are vulnerable to organizing change and stability but also building internal working system to trigger emotional responses (McEwen et al. 2013). It is a critical time for brain development and the PFC (McEwen et al. 2013). It exposes a selection of long -term modifications on brain development and behaviour (Entringer et al. 2009). Prenatal exposure to stress affects hormones in the body including the physiology and anatomy that relate to increasing drug levels, cortical communication and more (Entringer et al. 2009). Fetal stress is any event that interrupts a fetal process in stability in the body. (Entringer et al. 2009). During pregnancy, maternal stress impends the fetal nervous system and shortens the length of maturation due to many issues and concerns affecting the mother (Entringer et al. 2009). During pregnancy, maternal psychosocial stress threatens the fetal nervous system and contracts the length of gestation (Entringer et al. 2009). High levels of placental corticotrophin- releasing hormone

When reviewing the relevance of the article entitled “Diabetes in pregnancy among First Nations women” (Mayan, Oster, & Toth, 2014), it was discovered that important aspects of the study process such as its purpose, research questions, and significance were made very clear to the reader. The purpose of the study was to bring a greater understanding to why diabetes rates among First Nations women were higher than that of non-indigenous women and with that, find more suitable options of prevention and treatment of diabetes among this group (Mayan, Oster, & Toth, 2014, p. 1469). This statement was found to be very significant to nursing/healthcare because it was aimed at gaining a greater qualitative insight into a topic that has received

Gestational diabetes, affecting approximately 3-10% of pregnancies, is diagnosed by hyperglycemia during pregnancy in women without a history of diabetes. The underlying cause of gestational diabetes remains unknown, although the interference of pregnancy hormones, such as human placental lactogen, with susceptible insulin receptors, has been considered. The patients usually have few symptoms, and they are often diagnosed by screening during routine pregnancy check-up. For the mother, glucose intolerance typically disappears after the baby is born. However, gestational diabetes often places the body at risk. Babies born to mothers with poor hyperglycemia control are often at increased risk of series problems including macrosomia, which associates with a high chance of C-section, shoulder dystocia, hypoglycemia after birth, polycythemia as well as multiple chemical disorders.

Caring for yourself during your pregnancy when you have type 1 or type 2 diabetes (diabetes mellitus) means keeping your blood sugar (glucose) under control with a balance of:

Consequently, a large number of issues can and have arisen that have been caused by an increase in Glucocorticoids during prenatal development.

The research article has very detailed information on the research, while the general article has only superficial information. The research article has clear information about the test subjects, their age range, the duration of experiment and its effects. On the other hand, the general article does not even specify the information about the target subjects, their gender, age range and time duration.

Gestational diabetes is a disease that affects pregnant women it’s a glucose intolerance that is started or diagnosed during pregnancy. Based on recently announced diagnostic criteria for gestational diabetes, according to the American Diabetes Association, it is estimated that gestational diabetes affects 18% of pregnancies. Pregnancy hormones can block insulin therefore causing the glucose levels to increase in a pregnant woman’s blood. Gestational diabetes starts when your body is not able to make and use all the insulin it needs for pregnancy (American Diabetes Association). Without enough insulin, glucose cannot leave the blood and be changed to

During pregnancy, the positive feedback loop that plays a part in regulating products of the HPA axis is altered. Prenatal levels of cortisol and placental corticotropin-releasing hormone (pCRH) have been shown to be elevated during pregnancy. Placental corticotropin-releasing hormone is considered a “placental clock” that changes the development of the onset of parturition (Glynn, Davis Sandman, 2013). According to Glynn et al., these elevations have been linked to changes in the sensitivity of cortisol in the anterior pituitary and also to a decline in corticotropin-releasing hormone secretion centrally. Also, the HPA refractory period is shown to increase when additions of more extreme adrenal insufficiencies occur. A longer refractory

Gestational diabetes mellitus (GDM) is an intolerance of glucose documented for the first time during pregnancy. It is usually a short-term type of diabetes and the most common health problem with pregnant women. GBM is caused by the way the hormones in pregnancy affect the mother. GDM accounts for 5-7% of all pregnancies (American Diabetes Association, 2010). During pregnancy the placenta develops and becomes the main bond between the mother and the baby. It is used to make sure the baby has and gets enough nutrients. The placenta makes several hormones which make it hard for insulin to control blood glucose and block the action of the mother’s insulin in her body (American Diabetes Association, 2010). Hormonal changes during the

Women in their 30s had relatively consistent percentages of low, moderate, and high levels of cortisol throughout pregnancy. 60% of women in their 30s had moderate cortisol levels at the end of the 1st trimester, in addition to 26% having high levels, and 14% having low levels. At the end of the 2nd trimester, 61% of these women had moderate cortisol levels, compared to 31% with high levels, and 8% with low levels. By the end of the 3rd trimester, 57% of these women had moderate cortisol levels, 36% had high levels, and 7% had low