Preparation Of The ( 2 Nitrophenyl ) Acrylate Using The Wittig Reaction

Two forms of stereochemistry can form product for the bromination of trans-cinnamic acid. Cis addition, also known as syn addition, is one way of forming product. This form of stereochemistry allows for the components of the reagent to add to the same side of the double bond. Trans, also known as anti addition, is the second form of addition that can create product for this experiment. Tran stereochemistry occurs when the components of the reagent add to opposite sides of the double bond. In this experiment, the formation of either erythro-2,3-dibromo-3-phenylpropanoic acid (trans/anti-R,S or S,R) or threo-2,3-dibromo-3-phenylpropanoic acid (cis/syn-R,R or S,S) was expected to occur.

Objective: The objective of this lab is to observe the synthesis of 1-bromobutane in an SN2 reaction, to see how a primary alky halide reacts with an alcohol.

The mixture was heated at 120°C using an aluminum block and was stirred gently. After all of the solid dissolved, it was heated for 20 additional minutes to ensure the reaction was complete.

In the formation of stilbene dibromide, there are three possible products. The first is meso-stilbene dibromide in which the bromines are on opposite sides of the former double bond. The other two products, d-stilbene dibromide and L-stilbene dibromide, are enantiomers with the two bromines on the same side of the former double bond. As enantiomers, d-stilbene dibromide and L-stilbene dibromide are non-superimposable mirror images of each other. Meso-stilbene dibromide makes up 90% of the yield of this reaction, while d-stilbene dibromide and L-stilbene dibromide make up only 10%.

You may have done siinple experiments alkene can be quickly and easily differentiated from an alkane. to learn how an identified, and

6. Purpose: to clarify the mechanism for the cycloaddition reaction between benzonitrile oxide and an alkene, and to test the regiochemistry of the reaction between benzonitrile oxide and styrene; to purify the crude product of either trans-stilbene, cis-stilbene, or styrene reaction.

b. If it is too much the all of the solution will precipitate including the benzoic acid. If it is too little than then it will take a long time to heat the solution in order to acquire the benzoic acid.

The purpose of this experiment is to convert carbonyl compounds to alkenes using Wittig reaction. In this case we will be synthesizing Trans-9-(2-phenylethenyl) anthracene from benzyltriphenylphosphonium chloride and 9-anthraldehyde. We will also aim to obtaining a high percent yield and purity for the synthesis of Trans-9-(2-phenylethenyl) anthracene. The mechanism for this reaction goes thus:

Based on prior calculations, expected yield for the alkene products was 79.5%. The actual yield was not as high, resulting in a 28.4% yield. Even with this relatively small yield, the reaction still went to completion as indicated by the GC results in Figure 2. This is known because there is no presence of 2-methyl-1-butanol within the GC spectra. Only the two desired alkene products with

15. An alkene with the molecular formula C8H16 undergoes ozonolysis to yield a mixture of

In order to calculate the percent yield, we first had to determine the moles of the limiting reactant, which was anthranilic acid in this case, by dividing the mass of was anthranilic acid we weighted in the beginning of the lab (2.001g) and dividing it with the molar mass of was anthranilic acid. Thus obtaining the value of 0.01456g. Then in order to calculate the theoretical yield, we multiplied the moles of was anthranilic acid with the molar mass of N-acetylanthranilic acid and the mole ration which was 1:1, thus obtaining the value of 2.614g. Finally, to determine the percent yield, we divided the mass of the pure crystals with the theoretical yield and multiplied it by a 100, thus obtaining a 16% yield. Discussion and Conclusion The reaction of anthranilic acid lead to the end product of

The results of our TLC plate for point B is consistent with the nature of the sample, which is a mixture of the trans and cis isomers. Two spots were observed with considerable differences in their polarities. Point C produced two spots after our TLC plate procedure; that is an indication of impurity, since point C was supposed to be only composed by cis isomers. The second spot, was observed to have similar factors to point A, it is possible that the impurity is due to the isomerization of cis isomer to trans. The isomerization reaction for this compound undergoes by radical reaction.

In 1,3-disubstitution pattern, if both groups are in cis formation, they will be equatorial. Therefore, in this case, cis isomer is more stable. Chair flipping provides a conformation of cis isomer with both

According to the mechanisms suggested before Chauvin, the only possible products are ethylene and tetradeuteroethylene—along with cyclohexene. The pairwise participation of the carbon atoms in the mechanism prevents the formation of 1,2-dideuteroethylene. However, according to the Chauvin mechanism all three ethylene products should be formed and in a statistical ratio 1:2:1.

Equipment, Materials, and Method The equipment used were a jacketed batch reactor beaker, cooling water circulation system, computer, LabPro temperature probe and conductivity probe, mixing stand and magnetic stir bar. The materials used for this reaction were a 0.08M NaOH solution and a 0.1M ethyl acetate solution. A 20% excess Ethyl acetate was used to ensure NaOH was the limiting reactant.[1] NaOH was chosen for the limiting reactant because of its high conductivity relative to Ethyl acetate. The extent of the reaction was monitored by measuring the conductivity throughout the reaction. With NaOH being the limiting reactant, the change in conductivity is more visible, and the termination of the reaction can