Prescription Opiate Medication Literature Review

Opioid addiction is so prevalent in the healthcare system because of the countless number of hospital patients being treated for chronic pain. While opioid analgesics have beneficial painkilling properties, they also yield detrimental dependence and addiction. There is a legitimate need for the health care system to provide powerful medications because prolonged pain limits activities of daily living, work productivity, quality of life, etc. (Taylor, 2015). Patients need to receive appropriate pain treatment, however, opioids need to be prescribed after careful consideration of the benefits and risks.

Opioid use in the US has increased over the years, and this has led to an increase in substance abuse. Substance abuse is not only associated with use of illicit drugs but also prescription drugs. In 2015, of the 20.5 million reported cases of substance abuse, 2 million had an abuse disorder related to prescription pain relievers and 591,000 associated with heroin.1 The increase in substance abuse disorder has led to an increase in opioid related death. In 2015 drug overdose was the leading cause of accidental death in the US with 52, 404 lethal drug overdoses.2

The use of opioids and other drugs continues to gradually increase in the United State. According to Centers for Disease Control and Prevention (CDC), the number of overdose deaths involving opioids has quadrupled since 1999” (CDC website). Individuals are abusing prescription opioids such as oxycodone, hydrocodone, and methadone. Prescriptions opioids that are supposed to be used as pain relievers, cough suppressants and for withdrawal symptoms are being use by individuals in order to feel relaxed or for the overwhelming effect of euphoria. These types of drugs are to be taken orally, but people are snorting, smoking, and injecting them in order to get a better high. I have personal encounters with opioid drugs and opioid abuser on a regular

The most commonly abused substances are Nicotine, Inhalants, Alcohol, Cocaine, Amphetamines, Prescription medications, Heroin, Ecstasy and Marijuana. 1a(National Institute on Drug Abuse, 2011) Initially, a person may find themselves using substances voluntarily and with confidence that they will be able to dictate their personal use. However, over the period of time that drug use is repeated, changes are taking place throughout the brain, whether it is functionally

According to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5, opioid use disorder (OUD) is characterized by patterns of opioid use that are problematic and persist for at least one year (American Psychiatric Association, 2013). Evidence of problematic use of opioid is demonstrated through the presence of at least 2 symptoms which include withdrawal, craving, and continued use of opioids despite the disruptions it causes in personal and professional life. The substances used by persons with OUD are heroin and nonmedical pain relievers ([NMPR]; i.e. nonmedical use of opioid pain relievers), and estimates for DSM-5-defined OUD tend to combine the prevalence of use for each of these substances to determine overall

As previously discussed, the program the author would choose to evaluate is MAT treatment programs. This population consists of individuals that have been diagnosed with opiate use disorder, and receive opiate-substitution medications, such as Methadone or Suboxone. These program evaluations would be consumer-centered, performed in the clinics they receive services. Interested stakeholders would include the treatment center where the participants receive services, as well as other MAT service providers. Additionally, the funding sources for these individuals and program centers, such as county, state, and federal agencies, along with medical insurers, would also gain value from the program evaluation research.

The United States currently faces an unprecedented epidemic of opioid addiction. This includes painkillers, heroin, and other drugs made from the same base chemical. In the couple of years, approximately one out of twenty Americans reported misuse or abuse of prescriptions painkillers. Heroin abuse and overdoses are on the rise and are the leading cause of injury deaths, surpassing car accidents and gun shots. The current problem differs from the opioid addiction outbreaks of the past in that it is also predominant in the middle and affluent classes. Ultimately, anyone can be fighting a battle with addiction and it is important for family members and loved ones to know the signs. The cause for this epidemic is that the current spike of opioid abuse can be traced to two decades of increased prescription rates for painkillers by well-meaning physicians.

Almost one hundred years ago, prescription drugs like morphine were available at almost any general store. Women carried bottles of very addictive potent opiate based pain killers in their purse. Many individuals like Edgar Allen Poe died from such addictions. Since that time through various federal, state and local laws, drugs like morphine are now prescription drugs; however, this has not stopped the addiction to opiate based pain killers. Today’s society combats an ever increasing number of very deadly addictive drugs from designer drugs to narcotics to the less potent but equally destructive alcohol and marijuana. With all of these new and old drugs going in and out of vogue with addicts, it appears that the increase of misuse and

America has a major problem with opioid addicts, and many facilities are helping the addicts by providing safer options to taking the drugs their bodies crave. Methadone clinics are places where people addicted to opioids can receive medicine-based therapy. Opioid use, drugs such as heroin, morphine, and prescribed painkillers, has increased in the US with all age groups and incomes. People become addicted to these drugs when they are prescribed, recreationally used with other addicts, or they are born addicted. Many health institutions are addressing this issue with an estimated 2.1 million people in the United States suffering from substance use disorders related to prescription opioid pain relievers in 2012 and an estimated 467,000 addicted

An important part of overcoming the behaviors that go along with addiction is the creation of memories. Memories are created from the time we are born, we learn things about ourselves such as what makes us laugh or what makes us cry. A person may have a bad experience with a drug or alcohol and that memory stays with them. It could even deter them from trying it again or the person could be pressured into giving it one more try before they decide. Memories are actually “solid bits of protein imprinted on the brain as microscopic memory bumps called dendritic spines” (Inaba & Cohen, p. 2.12, 2011). When people use psychoactive drugs the memories are imprinted on the brain. These memories include, “where they got the drug, the reason they used it, and what feelings resulted” (Inaba & Cohen, 2011). These memories are problematic because they are

Substance abuse disorders have been considered a major epidemic by public health authorities during this century. Most recently, those who use, and abuse opioids have been in the spotlight. The growing number of overdoses, deaths, and individuals who are identified as opioid abusers has, of late, been the subject of media attention. Now coined “The Opioid

Opioid abuse, misuse and overdose is a problem in The United States. You can’t turn on the TV or read a newspaper without some mention of the epidemic. This issue has caused the practice of prescribing or taking narcotic pain medication to be looked at under a microscope. Patients are fearful to use some necessary pain medication, because they may become addicted. Other patients who genuinely do have pain and need medication are having a tougher time obtaining the help they need. The problem of abuse and addiction is tough to solve since for some people the medications are the only way they can function and live a semi-normal life. A patient with pain may be hesitant to visit the doctor and

Opioid addiction is a condition that is preventable as well as one which individuals display several noticeable risk factors before the actual addiction prognosis to the point of causing death. There is a strong correlation between the early misuse of prescription opioids, which are prescribed for non-cancer pain management, and the development of a dependence on such opioids. Early detection of risk factors such as the misuse of opioids that are prescribed will help indicate that a patient is developing an addiction.1 Physicians, nurses, pharmacists, and other healthcare providers must closely monitor patients and the rate at which opioids are consumed as well as refilled.

The two main outcome variables were the frequency of opioid use and the subjective “high” feeling reported by the participants. The opioid use was measured by a 0-3 frequency scale (0 = no use, 1 = 1-3 times per month, 2 = 1-3 times per week, 3 = daily/nearly every day) which was measured every 30 days during the six months of the trial. The subjective high was also measured on a 0-3 scale (0 = no high, 1 = not certain, 2 = some high, 3 = full high). Each opioid was analyzed separately (heroin, methadone, codeine, morphine, buprenorphine) as well as being summed as a composite (all opioids). Consideration was also given to opioid dosage, non-opioid substance use, criminal activity/behavior, depression, overall satisfaction with life and current

As a police officer, I am constantly exposed to the effects of drug addiction, specifically America's opioid crisis. Furthermore, I find myself pondering why someone is willing to inject a narcotic such as heroin knowing that it may be laced with a lethal dose of fentanyl. Consequently, the biology of an addict's brain becomes altered through repeated drug use, and narcotics such as heroin mimic natural occurrences within the brain permitting the attachment and activation of neurons (National Institute on Drug Abuse (NIDA), 2014). Additionally, some illicit drugs can evaluate dopamine levels as much as ten times the normal amount produced naturally by acts such as eating or sex, which causes addicts to seek the instant and prolonged effects of narcotics (NIDA, 2014). Since we are now aware of why addicts continue to abuse opioids, let us examine some of the statistics beginning with death totals.