Prodromal Phase

Hereditary Angioedema is the rarest of Angioedema’s and Urticaria is very uncommon with this type of angioedema. Hereditary Angioedema is a result of Blood levels of the protein C1-esterase inhibitor being very low. C1-esterase inhibitor protein plays a significant role in the regulating of the immune system and without it cases if our immune system. Hereditary Angioedema cases are usually Chronic rather than acute with very gradual development. Hereditary Angioedema It can be triggered by infection, trauma and

It was important to discuss with Lisa during consultation family history that could provide additional support for my final diagnostic conclusion .Going thru such topic area Lisa explain that her husband James dad was suffering with atopic eczema since childhood .This was quite an important piece of information as such conditions like atopic eczema ( dermatitis ) are hereditary conditions often (National Eczema Society ,2011).Atopic dermatitis or eczema is a chronic skin disorder inflammatory with pruritic skin that appears mostly on the face ,neck ,bends of the arms or legs caused by the malfunction in the skin barrier( NICE,2013).

History: Martha Wilmington, a 74-year-old woman with a history of rheumatic fever while in her twenties, presented to her physician with complaints of increasing shortness of breath ("dyspnea") upon exertion. She also noted that the typical swelling she's had in her ankles for years has started to get worse over the past two months, making it especially difficult to get her shoes on toward the end of the day. In the past week, she's had a decreased appetite, some nausea and vomiting, and tenderness in the right upper quadrant of the abdomen.

A 32-year old nurse who has rheumatic fever as a child noticed a persistent tachycardia and light-headedness. Upon examination, chest x rays showed an enlarged left atrium and left ventricle. ECG analysis showed atrial fibrillation. There was also mild pulmonary congestion. Cardiac evaluation resulted in the following information:

Affected infants can’t turn over, sit, or crawl. They also get startled easy to loud noises. As the disease continues they can experience seizures, vision loss, hearing loss, intellectual disability, and even paralysis. Usually they live into only early childhood. Seizures becomes a problem between ages two and five, with death at around fifteen years of age. Age of death is usually between 2 and 4 years, often from pneumonia.

Systemic Lupus Erythematosus, or Erythematous, also known as SLE, is a chronic inflammatory, autoimmune disease that transpires when the body’s own immune system assaults, with “variable manifestations”, it’s own tissues and organ systems throughout the itself1,2,3. This can also include joints, heart, lungs, skin, brain, blood cells, etc1. Systemic Lupus Erythematosus is known to have an impact on the organ network involved with immune complexes and multiple antibodies, especially antinuclear antibodies, or ANAs, an abnormal antibody that is targeted to cause certain edemas throughout the body and different tissues4.

Asthma is a disease of the lungs that can be influenced by different genes or alleles. When the epithelial or mucosal barrier is exposed to pollens, allergens, microbes or pollutants, these can stimulate the underlying antigen presenting cells (APC) which causes an immune response to occur.17 This can cause a cell influx into the airway that is primarily eosinophilic or neutrophilic. When the allergens present themselves, they can initiate a breakdown in the physical barriers, causing further allergic, inflammatory responses.

Choice “D” is not the best answer. Wiskott-Aldrich syndrome (WAS) is an X-linked recessive immune disorder with the characteristic triad of recurrent bacterial sinopulmonary infections, eczema (atopiclike dermatitis), and a bleeding diathesis caused by thrombocytopenia and platelet abnormalities. Mortality or infection from EBV is not directly increased in this

Rheumatic Fever is an inflammatory disease, caused by strep A when it is not cured correctly. About five percent of patients that have not been treated for strep A develop Rheumatic Fever. The immune system of a person with this disease is attacking bacteria, but also good tissue, usually on the heart. Children ages six to sixteen are most likely to get this. There is a high chance of dying from the disease if not cured correctly. Some symptoms may include; inflamed joints, fever, weakness, chest pain, rashes, chorea (abnormal movements/jolts) plus more. The diagnosis of Rheumatic fever involves a series of examinations by multiple doctors, looking closely at the symptoms of the patient and doing things such as chest x rays and heart monitors.

Hypereosinophillic syndrome (HES) is a rare condition characterized by peripheral blood eosinophilia with manifestations of organ system involvement or dysfunction directly related to eosinophilia in the absence of parasitic, allergic, or other causes. Any organ may be involved, including the heart, lungs, spleen, skin, and nervous system. Cardiac involvement causes a significant majority of deaths in severe cases.

Kawasaki disease is an acute vasculitis that occus in children under five years of age. It is a rare childhood illness but dangerous. The causes of this disease is still unknown. It often occurs in late winter snd early spring. The signs and symptoms of kawasaki is divided in three stage. Firstly, in early stage, patients have a fever that last more than five days, red tongue and swollen lips. Red eyes, body rash and swollen lymph nodes in neck are also appear during this time. After that, the skin of hands and feet are peel, joint paint. Some patient may also has a diarrhea or abdominal pain. The late stage, that signs and symptoms are appear around or more 8 weeks. There has some complication of kawasaki on heart, for example: vasculitis,

Emerged from the Greek word meaning, “blister,” Pemphigus is a combination of a potentially life-threatening autoimmune and Mucocutaneous disorder, gesticulated by intraepithelial blister formation (Kuriachan, 2015). Although the appearance may suggest otherwise, an interesting factor is that Pemphigus is not contagious by blood, fluids, or airborne aerosols (Kuriachan, 2015). Pemphigus is also not a genetic disorder. It is an exceptionally rare, autoimmune disease that affects a significantly confined percentage of the population. An autoimmune disease flourishes when your immune system, which guards your body against disease, decides your healthy cells are estranged (Roddick, 2016). This reaction threatens your immune system, and attacks

Phase correlation is simply a measurement of how the waveforms that you’ve recorded line up with one another.This becomes important when using multiple microphones to record the same sound source.

The disease is characterized by infiltration of foamy macrophages into various tissues with associated xanthogranulomas inflammation. ECD is a relatively rare condition with between 400-500 cases described in the published literature over the last 80 years. The disease is more common in men with one study showing 73% males out of 52 patients with disease reported [2]. Although the disease can present in children, most patients are diagnosed in

Bechet’s disease is a vasculitis disorder in which many organs and systems, including the heart, are affected; the etiopathogenetic pathway is not yet understood. Previously described heart lesions include: coronary arteritis, coronary artery aneurysm, granulomatous endocarditis, recurrent ventricular arrhythmias, myocarditis, valvar regurgitation, mitral valve prolapse, pericarditis, endomyocardial fibrosis, acute myocardial infarction, silent myocardial ischemia, intracardiac thrombus, left ventricular aneurysm, heart failure, aorto-atrial fistula, and amyloidosis[12]. Cardiac involvement exceed other clinical presentation in BD mortality, yet the clinical aspects remain unclear. To explore the characteristics of cardiac involvement in Behcet’s disease, we