Pros And Cons Of Gene Therapy

Gene therapy has saved many lives but there also have been other cases where the treatment has not helped cure the patient’s genetic disorder and they have died. Take Jesse Gelsinger for an example. He suffered from an X linked genetic disorder of the liver so he was injected with an adenoviral vector carrying the corrected form of the gene (Couzin & Kaiser, 2005). This treatment was not a success and Jesse ended up dying four days later. He suffered from a massive immune response that was triggered by the use of the adenoviral vector that was injected in him to transport the correct gene into his cells, which caused him to have multiple organ failures and his brain to die.

The altering of human genes could save lives. You could cure cystic fibrosis or alzheimer's. This would save the lives of many (Doc. 3). This technology could also give you children with specific traits of your choice. Also, this engineering can leave people painfree. This is not good because they can’t detect danger. As a plus side, scientists will eventually take the gene that causes this and help cure those with chronic long lasting pains (Doc. 2). This would make more people happy and healthy across the nation! Eventually we could go so far as to make a genetically engineered nation. As you can see, Genetic Engineering also could have a positive effect on

DNA has about 12 million single nucleotide polymorphisms and thousands of copy number variants, most of which are not harmful. Sometimes these mutations in genes can cause genetic disorders that end up altering or inhibiting protein function. Gene Therapy focuses on correcting the mutated genes usually by inserting a normal gene into the genome. Researchers treat these diseases this way by repairing dysfunctional gene or by providing copies of the missing gene. They isolate the normal DNA and package it into a vector. Other ways include replacing the abnormal gene with a normal one, repair the mutated gene, or altering the regulation of a certain gene. As of right now, reparative results have been marginal, there is potential of gene therapy treating single-gene disorders.

Ethically this could make many people happy and live better lives knowing that they won’t have to worry about as many diseases and the fact the they will live a long healthy life but this could also make make all the people that aren't modified sad because they have to live normal lives and will be seen as the superior people because the are more prone to diseases and other health issues. Just like Vincent Freeman he wasn’t allowed to go to certain schools and get his dream job just because he wasn’t genetically modified as a

Gene therapy provides many benefits to the patients who undergo it. Biotechnologists believe that a genetic disease can be removed with this treatment. For example, on the U.S. National Library of Medicine website, it states, “Researchers are testing several approaches to gene therapy, including: Replacing a mutated gene that causes disease with a healthy copy of the gene. Inactivating, or ‘knocking out,’ a mutated gene that

There are many ways to go about the process, and while there and pros and cons to both methods, gerund therapy stands as the most controversial. Supporters argue that the practice may eventually relieve human pain and suffering as it could eliminate all kinds of diseases. Others argue that gene therapy is just a new way of humans playing god which could damage the gene pool and cause even more disorders. Still others say that even if gene therapy does become largely used, there should be certain sanctions in place to determine what gene therapy should be used for. Regardless of one’s feelings on gene therapy, genetic engineering cannot be a solution for all of the world’s problems, reminding society that people are more than their genetic

Fifty years after the idea of gene therapy was first proposed, gene therapy has become a possible treatment for a couple different diseases. Before this treatment was approved, some serious unfavorable effects were found in clinical trials. However, these effects fueled more basic research in order to improve, in efficiency and safety. Gene therapy has been used for patients with blindness, neuromuscular disease, hemophilia, immunodeficiencies, and cancer.

(www.cancer.gov). If a mother and father both carry one altered gene, and one normal gene,

Whether gene therapy should be allowed to be used in practice is currently a very controversial topic. In my opinion, I do not think that it should be allowed. Gene therapy is a technique where genetic material is inserted into a patient to replace missing or defective genes. Gene therapy can be further broken down into two categories: somatic and germline. From there, somatic gene therapy can be approached in two ways: in-vivo and ex-vivo. For the process of gene therapy to begin, the proper vector needs to be acquired. Once a vector is chosen, the vector delivers the new gene into the target cell. Then, the target cell becomes infected with the vector. Next, the vector’s genetic material is inserted into the target cell. Then finally, functional

Gene therapy is an experimental form of treatment, where normal genes are placed into missing or defective ones in order to correct or alter genetic disorders. In other terms, it is the therapeutic delivery of nucleic acid polymers into a patient 's cells as a drug to treat disease (Gennady, 2015). After many attempts at modifying human DNA by nuclear gene transfer as well as insertion of human DNA in the nuclear genome, the first successful gene therapy was in 1990 where it was used to cure four-year-old Ashanti DaSilva who had Severe Combined Immune Deficiency (IDF 2013 National Conference). Since then gene therapy has been used to cure and treat serious diseases such as Chronic Granulomatus Disorder, Hemophilia, and a wide variety of Cancers, and other genetic and acquired diseases (American Society of GENE & CELL THERAPHY, online).

Therefore, as a result of extensive regulations put forth and overseen by political authorities, Gene therapy has had a profound political impact. Its political ramifications can be seen to be positive as the legalities surrounding Gene Therapy ensure the protection, safety and security of any individual undergoing the clinical trial.

If a treatment is implicated before the child is born – germline gene therapy – he or she could lose all trace of that defective gene, and therefore wouldn’t pass the disease on to future generations. In somatic gene therapy, treatment is conducted when the patient is an

disease (NLM, 2014). The procedure uses a corrected gene and inserts it into a person instead of

    Through recombinant DNA techniques, scientists have already experimented with bacteria and copied their cellular system that allows them to defend themselves from viruses in order to create a new restriction enzyme called Cas9, which then gets bound to an RNA guide strand. This new enzyme introduces new genetic material into the human genome as DNA replicates. This method will be useful for families members who carry harmful recessive alleles. Their babies could inherit the genetic disorder, but with recombinant DNA techniques, the harmful gene or genes could easily be replaced with a functional gene. Lauren Friedman, Senior editor for

Every living thing is the product of the genes that were passed down from ancestors. Genes make up everything we are. One gets their traits from their parents. Most people live full lives with relatively good health. However, some people inherit mutated genes or faulty genes. This could lead to genetic disorders that could be life threatening. Even today, many genetic disorders still remain incurable, leaving many people without hope. Genetic therapy could be their answer. It is through this research that the cure for genetic disorders can be found. Though some people believe it is unethical or immoral to alter genes, current therapeutics have not been able to save the lives of the patients with these diseases. Genetic therapy