Psoriasis : The Genetic And Immune Mediated Implications

The Integumentary is a vast organ system composed of exocrine glands, hair, nails, and the most commonly known organ, the skin. As a large system, it can be susceptible to many different types of diseases, one of these diseases are called Psoriasis. This affects a large portion of the Integumentary system, the skin. Psoriasis are considered to be a widespread, common and recurring disease that can be chronic at times. Psoriasis are defined by its appearance of light silver in color, flaky, rash on many parts of the Epidermis.

Psoriasis is as the author of the article “Update on Psoriasis and its Management” states, a genetically inherited chronic inflammatory

So far, 25 genetic variants have been identified that make a person more susceptible to getting psoriasis (Genes, 2015). Based on these findings, it has been determined that about 10% of the population are a carrier of one of these genetic variants, but only 2-3% of the population will experience a trigger that causes the disease to present itself. These triggers include stress, skin injuries, certain medications, and infection (specifically a correlation has been found between the streptococcus bacterium and patients that present with psoriasis) (Psoriasis, 2015; Genes 2015). Of the people who are diagnosed with psoriasis, 30% will develop psoriatic arthritis. This condition comes with an increased risk of cardiovascular diseases, depression, cancer, crohn’s disease, and

The physician, Galen identified psoriasis as a skin disease through clinical observation. He was the first to call the disease psoriasis. The Greeks has a word for it -psora meaning “to itch”. In 1809, Dr. Robert Willan first recognized psoriasis as a specific clinical entity. Psoriasis is knows as a skin order that forms thick,red, bump patches that are covered with silvery scales. They can appear anywhere on the body,but mostly on the scalp,elbows,knees, and lower back of the body. No one really knows the cause of the disease. However, experts do believe that it has something to do with the immune system that causes inflammation that is triggering new skin cells.

Psoriasis is a skin disease of the integumentary system that has no cure. This skin disease can leave the outer layer skin red, itchy, with scaly patches. It can also lead to skin infections in severe cases. In the journal “A New Holistic Approach To Treating Psoriasis” by Colleen Mikula tells about psoriasis and the different treatments that are used to treat people with this disease.

Psoriasis is a chronic skin disorder than can happen to most adults. Psoriasis happens when the cells rapidly build up on the surface of the skin causing the skin to become thick, silvery scales and itchy, dry, red patches that are sometimes painful. These symptoms are often found on the elbows, knees, legs, scalp, lower back, face, palms and soles of the feet. However, they can also show up in other places as well, such as the fingernails, toenails, genitals and inside of the mouth. Psoriasis is a lifelong disease that can be treated.

As previously stated, Psoriasis is caused by a mistaken trigger in the Immune system. “Normally, T cells help protect the body against infection and disease.” (NIAMS, 2013) When the disorder triggers the immune system, it causes the T cells to activate and trigger other immune responses. This will develop the redness and scaling of the

Psoriasis is without doubt one of the most long-established dermis issues and might occur on just about any a part of the physique, together with the penis. When a character has psoriasis, the dermis cell's life cycle is affected; it causes the cells to overproduce, making a construct-up on the surface of the skins

Psoriasis is the chronic inflammatory condition that occurs as part as of a complex set of the interaction between genetics, immunological, systemic and environmental factors (Green, 2011; Penzer & Ersser, 2010). Psoriasis is not contagious like all chronic condition (Penzer & Ersser, 2010). In the Caucasian population, the population that get psoriasis is about 2%.

From helping to dress my mom to getting my youngest siblings ready for bed while my father was at work, I certainly understood the devastating toll autoimmune disorders could have on, not only the person suffering from it, but their loved ones as well. That first year after my diagnosis was the hardest on me emotionally, while being engulfed in scaly plaques changed my physical appearance, it dramatically affected my self-esteem and overall happiness, and by the end of the year I rarely left my room. I knew that serious health conditions posed a threat in patients with severe psoriasis, but, like most teenagers, I was convinced nothing would happen to me. After what seemed like an eternity of hoping my symptoms would naturally vanish, I was exhausted, I was done letting psoriasis control my life. Thereafter, I began seeing dermatologists and with help from my mother, discovered the world of holistic medicine. While conventional medicine helped, I really began seeing changes in not only my skin, but my overall happiness, after I took an alternative

Psoriasis is a perplexing, reoccurring immune system disorder described by red, flaky patches on the skin. Those living with psoriasis need to battle the urge to scratch the red, flaky, and bothersome patches of dry skin consistently. In any case, that doesn't mean the condition needs to assume control over your life.

Psoriasis is a disease that greatly affects a small amount of the population. It is estimated that about 3-5% percent of the population is diagnosed with psoriasis (Yu, 2016; Pg. 1). Psoriasis is defined as a chronic inflammatory skin disease (Lahousen et al, 2016; Pg. 78). The disease creates, in most cases, rough dry patches or lesions on the skin surface. Multiple sights on the body can be affected ranging from the scalp, face, and nails (Wade et al., 2016; Pg. 1). Though the disease largely results in physical symptoms, many patient’s health-related quality of life (HRQoL) is affected as well; health-related quality of life is an evaluation of how a person’s health affects aspects of life, mainly focusing on social, psychological and cognitive functions (Gonzalez et al., 2016; Pg. 2). This paper will examine multiple literatures in order to explore the connection between a patient’s health-related quality of life in regards to a diagnoses of psoriasis.

Psoriasis is a potential inherited genetic defect in the immune system. It is an unpredictable skin disorder that is characterized by painful, itchy, patches of redden skin covered in white skin scales. It affects millions of people around the world and there isn’t a cure for it.

Psoriasis is a type of noncontagious chronic dermatitis. The types of individuals that can be at risk for psoriasis has a mixture of genetic predisposition and types of environmental factors, individuals with immune regulation defects are most likely to obtain this condition; Most causes for psoriasis is unknown by doctors. Whithin this condition there is several different forms of psoriasis including;

Psoriasis was copied from the Greek word psora, which means “to itch” (Jean, 2011). Psoriasis is a chronic, long lasting autoimmune skin disease that disturbs the speed of the growth cycle in skin cells (Stress-Related Disorder Sourcebook, 2016). Normal, healthy skin cells replace dead skin cells every twenty-eight to thirty days (Langley, 2005). Skin is the largest organ in the body. It protects from the environment, regulates body temperature, helps coordinate immune system regulation, function of touch sensations, waterproof, and prevents toxin substances from entering the body (Langley,2010). Psoriasis effects greater than three percent