To develop and understanding of quercetin I had read regular websites and news articles to obtain background information, and not focusing on whether it was peer-edited or credible. To obtain solid evidence I then search for peer-reviewed scientific journals that were either research or review articles. Using databases I was able to acquire these articles. Databases used were the University of Toronto Articles and Databases, Google Scholar and the School of Nutrition. Keywords searched: quercetin, blood pressure, cardiovascular disease, supplements, hypertensive, and flavonoid. Most of these keywords were used in combinations. From the evidence recovered it seems to show that the supplementation of quercetin is capable of decreasing blood …show more content…
Searching for peer-reviewed articles on quercetin and blood pressure only drew up six well carried out studies. This was a large limitation since the research is so limited, more tests and trials need to be conducted. Another limitation would be that there are many animal studies and not enough human studies. Larson et al. (2012) found quercetin reduced oxidative stress in rats, and that in human studies they could not make general assumptions due to the difference in quercetin plasma levels. The amount used in animal studies would require there to be a 10-30 fold increase in quercetin plasma in a human, which is possible to achieve from diet alone but the individual would have to be on a strict one. Now quercetin has been found to be generally safe, but at high levels, especially while on specific medications it can have an inhibitory effect which could result in kidney …show more content…
The sample sizes in the studies need to be increased in order to achieve statistical precision and reduce the standard errors (Askari et al. 2012, Edwards et al. 2007). Also, many of these studies are homogeneous, focusing on the middle-aged, Caucasians. This does not take into the consideration that the human genome varies between individuals, and selecting on a criterion of one ethnic does not give a good generalization. Besides the selection of the participants for the study, it also seems that in order for quercetin supplementation has blood pressure lowering effects of a certain range in an individual (Edwards et al. 2007). Another controversy is the relation between quercetin and endothelial function. Askari et al. (2012) found that there is no relationship while Egert et al. (2009) found that age impacted the association. The younger individuals had an improved endothelial function, possibly due to the mechanisms that occur in younger adults versus older adults. Another limitation is that these studies go no longer than 2 months, and 2 studies have confirmed that quercetin does not have any acute effects (Egert and Rimbach 2011, Edwards et al. 2007). Yet, due to a limited length of study the long-term impacts are unknown and if using quercetin for a long time period shows greater improvement. I propose that these limitations found do not
Throughout the years we have been prescribed with regular medications for whatever illness we have and also in using supplements for our weight loss program. We at times neglect or willfully forget the side effects and risks we are faced off with regular medications. This is the reason why a lot of herbal supplement companies are increasing in popularity because of the supplements they are recommending in exchange of the regular medications. There are more and more people being aware of these supplements performance. They prevent the onset of a possible health problem and also increase performance with considering very little complications or side effects.
What impact does the illness have on the blood’s ability to clot? Include the role of vitamin K and the specific clotting proteins affected. Also discuss platelet production. Describe the test that is typically run to test the blood’s clotting ability.
Overall both treatment groups were equal in size. Both treatment groups had an almost equal average age of study participants, this is important because inequality in age between the groups would represent a heterogeneous population (Barker 2010). Venous leg ulceration is more common in woman than men in those below 85 year of age (Moffat 2004)
Based on this 2011 documentary featuring the numerous statistics and examples from physicians on their patients making changes to their health, showed the high improvements on their health after a few weeks on a plant-based diet. They showed not only the crucial medications and prescription drugs the patients were each taking, but they helped them create exponential changes to their cholesterol, weight, and health problems of their western diet that made it possible for them to no longer take them. This documentary captured the many risks people can get such as diabetes, heart disease, arteries of blood clotting, cancer, high blood pressure, osteoporosis, and much more in which costs the United States more than a million dollar each year. According
Cardiovascular disease has become one of the leading causes of death worldwide (1). In their textbook, Smolin and colleagues state that “resveratrol […] may help to prevent cardiovascular disease” (2, p.479). Indeed, observational studies have provided evidence that populations that regularly consume substantial amount of the compound resveratrol also have a lower incidence of cardiovascular disease (CVD) (3,4). One meta-analysis calculated that drinking 150 mL of red wine (containing resveratrol) per day provided the optimal protection from cardiovascular disease (5). However, no experimental evidence exists to directly link resveratrol supplementation with incidence of cardiovascular disease. A growing body of experimental evidence
The study only involved about 120 subjects--quite a small sample size relative to most research of significance. Still, they did establish that patients taking the placebo medication experienced the predicted Abeta40 decline in the CSF, while those receiving the resveratrol treatments showed little to no change in their Abeta40
Quercetin is a natural flavonoid in many foods, including apples, cranberries, blueberries, and onions. Quercetin may have many beneficial biological properties like, anti-inflammatory, anticarcinogenic, cardioprotective, and neuroprotective. There is also considerable interest in quercetin’s potential
The problem of hypertension is growingly becoming a major reason for worldwide mortality and morbidity. The problem may not be externally visible in a person who is suffering from it but internally it can cause stroke, cardiac failure and kidney problems. It has been predicted by experts that the number of people suffering from hypertension will grow by 60 percent by the year 2025 and the major risk factors linked to the problem are diabetes and obesity. Although the condition is globally prevalent and intense research are being made into it, no signal cure or effective treatment can be found which can protect body from hypertension without having any side effects. Exercise to reduce hypertension and herbal pills to reduce hypertension offer the best and risk free ways to regulate the condition.
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This indicates that the metabolism of proteins was apparently affected by Ch.t extract. The improvement on the levels of protein and albumin in the diabetic treated groups show that Ch.t extract have significant effect in glucose and protein level because insulin inhibit gluconeogenesis from protein [ ] or could be due to improvement in renal function. This affirmative agrees with the fact that the weight of skeletal muscles was significantly increase in diabetic rats treated with Ch.t extract. The decrease in albumin level documented for diabetic rats may be due to liver massive necrosis, deterioration of liver function, hepatic resistance to insulin and glycogen impairment of oxidative phosphorylation[ ].Under the same experimental conditions serum globulin level revealed an appreciable decrease[ ]. The renal pathogenesis is related to duration of diabetes, the most devastating complication with diabetes is nephropathy[
Heart disease is the number 1 killer in the United States of America. It’s important to have a heart protection strategy, especially as you get older. It should include exercise and a healthy diet, plus supplements for heart health as needed. Know your cholesterol, blood pressure and ideal weight. Lower risk factors and prevent early disability, illness or even death from heart disease. And although you can't help heredity, you can certainly be aware of any risk factors that may have been passed down through your family tree. After following the steps in this assignments all of the supplements I would recommend along with the information I have given you here are proven to help in preventing heart health. Most can be safely taken in combination.
The experiment itself was also not conducted in a controlled environment as each participant was tested in different environments, which once again effects the internal validity of this study. Bias is also evident in this article, which consequently impacts the reliability of this research. The drug Meriva is mentioned more heavily than the drug chondroitin. The unsatisfactory amount of information on the drug chondroitin makes it difficult for readers to thoroughly to grasp the full understanding of the drug itself. The hypothesis and conclusion were not clearly evident or even stated within the research article and therefore, this consequently effects the validity and reliability. The procedure explained in the article was vague and contained little detail about how the method was
Modern medicine and healthcare system have categorized herbal medicine as a natural remedy used when people can’t afford to purchase conventional drugs. They are perceived inferior because they cost less but the health benefits are endless. However, there have been various situations and instances that prove that herbal medicine is good for health.