R01 Research Proposal Essay

Many companies allow for a trial period to see if the user enjoys the product or not. Throughout this trial period we could survey the customers and employees to see if the GPS really made a difference or not. This task may take longer than estimated due to trial and error. It might take trying a couple different companies to find the one that would be easiest to implement and maintain.

Working within a care setting with vulnerable elderly service users can create a relationship consisting of trust, familiarity and reliability. This in some cases can lead to service users becoming subject to abuse, this can be anything from, physical, sexual, psychological, financial or material, discriminatory, neglect and omission (SCIE, 2013).

The purpose of this experiment was to observe the differences in the formation of simulated blood clots when different amounts of sodium citrate, an anticoagulant, was added to the coagulation process, which would help gain information about the process that could potentially be used to create medications for different blood clotting disorders.

Targeting the FIX, FXI, and FXII appears to be a promising approach to decrease the atherothrombosis and thromboembolic events. However, in-depth knowledge of the proteins and other factors involved in the process of thrombus formation is crucial to design a safer and efficient therapeutic strategy by targeting these novel targets. The clinical trials are ongoing/recruiting the patients to understand the atherothrombosis, role of oral anticoagulants, and the influence of the proteins of the contact activation system on thrombus formation in human blood in a flow and static model (NCT02785718, FXI and FXII); embolization and degradation on collagen in a perfusion flow model (NCT01114074, FXI and FXII); randomized multicenter trial to

As a Hemophiliac, I have always had an interest in pharmaceuticals and healthcare because they have had such a pronounced impact on my life. Growing up with a disability was difficult because I didn’t have a lot of access to information, but I see myself in a unique position to help pharmaceutical companies in the bleeding disorders space assuage this information gap. Health complications related to my Hemophilia over the past year and a half have only amplified this interest.

Hemophilia, sometimes known as “bleeders’ disease” or “the love of blood”, is a genetic blood clotting disorder that causes abnormal, excessive bleeding. Approximately one in 10,000 males born in the US has hemophilia and it equally affects all races and socio-economic groups (Bellenir 96). A person with hemophilia, or a hemophiliac, has either an inactive or inadequate supply of one of several factors needed for blood to clot normally. The most common type of hemophilia is caused by the absence or malfunction of one of these proteins, called factor VIII (Griffiths, 2005). The result is increased bleeding after trauma and injury, or even spontaneous bleeding with no apparent cause. Depending on the level of these factors in the blood, hemophilia can be mild, moderate, or severe.

Coagulation, a cascade system abundant in fibrin and thrombin proteins that are vital to hemostasis4, mainly occurs on the vascular surface because the rupture on the surface causes a successive activation of trypsin-like serine proteases which lead to the release of thrombin and clot formation3. The coagulation system may be activated via the intrinsic pathway, where plasma factor XII triggers coagulation to begin, or the extrinsic pathway, where thromboplastin released from tissues stimulates plasma factor VII –– once each pathway activates plasma factor X, a common pathway leads to the conversion of fibrinogen to fibrin4 (this conversion is a function of which thrombin is responsible for3). To prevent excessive bleeding (which occurs when there is a scarcity of thrombin5) and/or unwanted blood clots (which occurs when there is a plethora of thrombin5), coagulation must therefore be highly regulated3.

According to the Census Bureau, approximately 49 million Americans didn’t have coverage in 2011. The Patient Protection Affordable Care Act has only been extended to cover 32 million uninsured individuals mandates. The main issue of access to affordable care will be to exacerbated by the limited community- based resources that provide preventive services, primary care access and the continuum care for patients with chronic conditions ("Income, Poverty and Health Insurance Coverage in the U.S.: 2014", 2015). There is a need to increase capacity to serve more patients while improving outcomes and reducing cost. Health disparities in the U.S. range from HIV/ Aids to obesity. The minority population typically has a disproportional burden of the HIV/ Aids epidemic ( Wetle & Scanlan 2013). Disparities in health care are among the lines of access to care, treatment, preventive measures, and medicine. Within this research project were used to examine how one 's race, neighborhood, or social classes affect their quality of care, and health outcomes ( Wetle & Scanlan , 2013). It was found that people who lived in lower-income urban areas were found to have a lower quality of care. The study also found that these people were also prescribed stronger more dangerous medicine, and also paid higher co- pays. The Affordable Care Act was created to target, and eliminate health disparities (Adepoju , Gonzales , and Preston 2015). The ACA

My broader research interests lie in the areas of international and comaparative political economy, applied game theory and quanttitative methodology. My current research projects focus on the simultaneous interaction between politics and economy at both the national and the international levels. I am particularly interested in the dynamic relationship between economic liberalization and political survival of authoritarian regimes. I also have a special interest in East Asian politics, particularly Chinese politics. During the fellowship years, I plan to develop my dissertation on foreign direct investment (FDI) liberalization and the political economy of authoritarianism into a book manuscript after

Urban farming is said to be “the practice of cultivating, processing and distributing food in, or around (peri-urban), a village, town or city” [1]. The focus of urban farming is largely based upon a daily demand for food from customers within metropolitan areas through the utilization on intensive production methods, using and reusing natural resources and urban wastes to yield a diversity of crops and livestock. There are plenty of initiatives promoting urban farming around the world

This proposal’s purpose is to gain approval to write a recommendation report on improving the locker program at the PCC Southeast campus. We will send this report to Josh Peters-McBride, who is the Director of the Student Life and Leadership Programs at Southeast.

Thanks to your support, the year 2017 has been one of growth and innovation for the Julia Robinson Mathematics Festival. We continue our expansion and fulfillment of our mission to bring the joy and beauty of mathematics to as many students as we can, through non-competitive extra-curricular mathematics activities.

This information could be used or serve of use to the area of health care related to endocrinology.

In 16th of August 2012 RM Research became listed in the NZX50. The company a research company based in Auckland New Zealand. They specialise in the following research disciplines:

People are born and lured into the world to become social from the very beginning. Some claim they do not have a social life but any type of communication is social. In college, people are social because they interact with professors, students, and the people around them. Some students might perform better in school when they are around others. They meet with others and form study sessions as a group. Other students might find if better if they find a peaceful place and study alone. Literature reviews are important because it gives researchers a better understanding on what is out there and how to improve a topic. An aspect in social life that I would like to study has to do with the benefits in class performance when students form study groups than when they study individually. There are methods and literature reviews that can help me determine which will boost a student’s performance the most.