Rapid Single Nucleotide Polymorphism Mapping

My genogram has three generations and includes the most important or influential people in my family life. The genogram includes my grandparents on both my dad and mom’s side, my parents, their siblings, and spouses, and on the bottom row, my siblings and I. My family has had unique challenges personally and systematically that created a stronger bond as the years went on. Though, today, we are spread out around the country, our familial connections have been strong overall.

Through my current experiences serving the less fortunate, volunteering at Etobicoke General Hospital, and participating in the Syrian Refugee Committee, the importance and benefit of scientific research has become clear. I enjoy challenges because it is through these trials that our motivation and intellect are improved. I would greatly accept the challenge The Helix Summer Science Institute offers, because I would have the opportunity to develop an understanding of the effects of genetic mutations in conserved human disease genes, and the importance and use of C. elegans as a model organism. This program is an exceptional foundational opportunity for the preparation process towards medical

A genogram is a type of family tree, but with more detailed information. It is often used as a diagnostic and assessment tool by physicians or counselors to obtain individual and family history in order to help in the establishment of a diagnosis and treatment plan.

Part 3 of this experiment calls to isolate the DNA from C. Elegans. To do so, we start by labeling three PCR tubes with the group number. One of the tubes is labeled “W” for wild type, one is labeled “R” for

A genogram is a diagram that shows family members and their relationships. The information can sometimes include, ages, dates, deaths, and or geographic locations. Males are represented by squares and females are represented by circles. The horizontal lines indicate marriage; while the vertical line indicates parents and children. This paper outlines the assessment and analysis of the three generation of the Jones and Sheffield family, relationships, structures, and health struggles. The interview was conducted by myself (Katroya) and the interviewer was my mother (Sheryl).

This examination compiled the following information: Grandmother “C” has BRCA1 trait resulting in double mastectomy at age 35, prior to diagnosis Grandmother “C” only medical condition was hypertension,. Mother “M” information was obtained. Mother "M" provided the

In recent discussions of medical advancements, a controversial issue has been genome mapping poses risks to its patients. On the one hand, some argue that it is going to be time consuming and costly. On the other hand, however, others argue that this can be a breakthrough in medicine. In sum, then, the issue is what America’s next step towards medical advancement is going to be. While some believe genome mapping poses many unseen risks, genetic testing can help identify unsurfaced illnesses.

The two recessive alleles are both on the same chromosome. Genes A and B completely follow Mendel’s principles of inheritance; genes B and C are physically connected together and never are separated from each other at any time during any cell division cycle or fertilization event. Draw below the gamete genotypes that this individual could produce.

What is your gene similar to? What is the ORF sequence name of the C. elegans homolog (i.e. ZC101.2)? If there is a gene name (i.e. unc-52), what is it?

The Drosophila melanogaster is an ideal organism most often used to study genes and mutations. The genome of the D. melanogaster, is similar to that of humans, making it the very beneficial to study. Through the studies done on the fruit fly, we are able to get a better understanding as to the processes of modern issues such as Alzheimer’s and cancer, in order to study and develop cures. Not only is the D. melanogaster an ideal organism based on its genetic similarities to human genetics,

There is much speculation as to where humans today came from, until recently much was up for debate when considering where one came from. The film, The Human Family Tree, directed by Chad Cohen, produced by the National Geographic Channel in 2009 attempts to answer the question: Where did we (as humans) come from? The film’s answer to this question comes from the Genographic Project which aims to uncover the origins of humans as a modern species. “The Human Family Tree” argues that modern humans originated in Africa around 200,000 years ago. The film uses the evidence provided by the Genographic Project to support their claim.

A forward genetics screen occurs when one starts by determining a biological process of interest, produces a mutagenized population, screens for phenotype of interest, analysis a mutant with a specific phenotype, maps the gene of interest, and conducts more screens to identify other genes that are associated with those mutants. And a reverse screen is when one has the analysis of a gene and studies the phenotype associated with it when it is mutated. To complete this experiment a forward genetics screen is needed. The materials needed are C. elegans, 20 plates to place and transfer the worms, 20 mini plates to place and transfer the worms, a microscope to view the worms, a glass pipette and a piece of platinum wire to create a worm pick, a bunsen burner to sterilize the pick, a notebook and pen to record the data obtained, and a lock to secure our experiment. The purpose of this experiment is to obtain multiple mutagenized C. elegans and allow the P0 generation to grow to a F2 generation and observe if there were any egg laying phenotypes present. To complete this experiment, I would first place a single mutagenized N2s in each of the POA1-POA5 plates. After 12-24 hours have passed and the eggs have been laid, I would move the 5 adult worms who were originally placed in each of the POA1-POA5 plates to POB1-POB5 plates according to their number. After the PO generation have grown a

Genetic and genomic variations are being taken into consideration when referring to nursing interventions for patients. In the discussion paper, “Individual Genetic and Genomic Variation: A New Opportunity for Personalized Nursing Interventions” by Munro (2014), the author examines the potential for genetic and genomic variations being incorporated into nursing interventions for patients. According to Tremblay and Hamet, “Genomics include interactions among genes, intergenic regions, epigenetic factors and environmental factors” (As cited in Munro, 2014, p. 36). The study of these genomics revealed that genomes are able to respond to environmental influences. Complicated genome-environmental interactions could be presented by cancer, diabetes

Many researchers have studied the short allele variation of the gene. Though most of have different views of how the serotonin transporter gene is related to emotions, most agree that the gene has some factor in emotion regulation. Some focus on the gene being a factor in the amount of depression, anxiety, and stress. (insert citation) Others explore the gene determining the amount of satisfaction within a person’s life. (insert citation) Some also explore the possible solutions or affects that could change the negative impact the short allele gene has on the way we think. (insert citation) The results of these experiments play a role in the discovery and evidence of the gene having a link to our emotions.

DNA fingerprinting is a scientific technology involving the extraction, replication and arrangement of strands of an organism’s DNA. This results in the formation of a genetically distinctive fingerprint that is unique to the organism which the DNA sample was originally extracted from. Because of the specificity of a DNA fingerprint, the application of this technology can have a substantial influence on many aspects of society. Accessibility to a DNA database allows for higher efficiency in forensic investigations, personal identification, maternal and paternal testing. The availability of a national database to police officers and forensic scientists would equate to increased productivity in investigations and prosecution of suspects in a