Sickle Cell Anemia is a very serious disorder and people suffer from it every day. It is a genetic disorder that causes the hemoglobin in the red blood cell to distort and form into a sickle like shape. The name comes from the shape of the blood cell after it is mutated. A person who has sickle cell anemia got it from inheriting from the parents. It is the most common inherited disorder in the United States. It is also has four other names this disorder can go by HbS, Hemoglobin S Disease, SCD, and Sickle Cell .(https://ghr.nlm.nih.gov)the blood cell is formed wrong turning it into a sickle or crescent shape. Sickle cell is only a disorder. It can also be treated a lot of different ways.
1.Full blood counts: To assess the Hb for evidence of anemia, WBC for evidence of infection.
How are you? You gave a good response to this week's discussion question. In which you state, "There are four different types of anemia". I agree that there are four anemias that are commonly known. However, there are more than four hundred kinds of anemia (1). It is amazing how one illness can have so many manifestations. I hope this helped.
Plasma would carry white blood cells, red blood cells, and platelets to the injury site, which is the scrape on the hand. Platelets would attach with each other, building a blockade to stop blood flow at the injury site. White blood cells would attack and kill foreign substances that enter through the injury site and try to hurt the body. Red blood cells would provide oxygen at the injury site to help heal the injury, having that platelets have created a blockade.
Sickle cell anemia mainly affects people with African, Mediterranean, Middle Eastern, and Indian ancestry. A person with sickle cell anemia inherits two sickle cell genes, one from each parent. It cause the red blood cells to change and become crescent shaped. Normal red blood cells are disk shaped and move easy through the blood vessels. The primary problem is hemoglobin, it is a protein molecule in red blood cells that carries oxygen from the lungs to the body’s tissues and returns carbon dioxide from the tissues to the lungs. In sickle cell anemia, the hemoglobin is flawed. The cells become sickle shaped and can’t move as easily through blood vessels. Sickle cell anemia has one main cause, in order for sickle cell anemia to happen, a sickle
Sickle Cell Anemia (SCA) is a gene mutation that is autosomal recessive and it affects red blood cells. This means that an individual must inherit two copies of the mutated gene for sickle cell anemia to have the disease, one from each parent. To be a carrier, you must possess one copy of a normal gene and one sickle cell gene. This mutation is a substitution or point mutation, meaning one nucleotide is replaced with another. In sickle cell anemia, an adenine is replaced by a thymine. The goal of this investigation was to use gel electrophoresis and a UV light to observe sickle cell anemia. The guiding question was “Which individuals have sickle cell anemia?”. A mother, father, and child’s DNA was tested and compared to known DNA that was
Anemia is a condition in which the concentration of red blood cells or hemoglobin in the blood is below normal. Hemoglobin is a substance in red blood cells that carries oxygen to the tissues of the body. Anemia results in not enough oxygen reaching these tissues.
What is Sickle Cell Anemia? Sickle Cell disease is a blood disorder that is inherited. By inherited I mean passed down from parents to their children. Babies are usually born with sickle cell disease. When they inherit two abnormal genes, one from each parent. Abnormal genes cause the body’s red blood cells to change shape. This being the effect of having sickle cell disease.
The clinical presentation of patients with aplastic anemia includes symptoms related to the decrease in bone marrow production of hematopoietic cells. Specific manifestations include pallor, headache, palpitations, dyspnea, fatigue, or ankle edema (Porth, 2015). Signs and symptoms of aplastic anemia may include nosebleeds and bleeding gums, frequent or prolonged infections, and pharyngeal ulcerations. Patients with aplastic anemia commonly present with symptoms of pallor, headache, palpitations, dyspnea, easy bruising and fatigue (Porth, 2015). Other symptoms include visual disturbance due to retinal hemorrhage, petechial rashes, SOB with exertion, dizziness (Porth, 2015). Patients with aplastic anemia also present with jaundice and evidence of clinical hepatitis (Porth, 2015). Obtaining work history, solvent exposure, as well as a family, environmental, and infectious disease history (Musser, 2006). The clinical presentation of
Describe the molecular nature and the inheritance pattern of the disease/disorder, ensuring to cite the original research paper that first identified specific genetic & molecular nature of the disease.
At first, I would like to say Taina not worry about getting dropped from the team since it should not happen. Even if she is a carrier of sickle cell anemia, the coach would not drop her nor the scholarship. Practice plans for sickle cell anemia carriers would change to less intensive, and the coach could teach them how to control the breath. Sickle Cell anemia is about Oxygen circulation in one’s body, so you should be fine if we can balance it after finding it. Sickle cell anemia is caused by genetic disorders of hemoglobin that is responsible to transport Oxygen to other parts of our body. Red blood cells of patients with this genetic disease become sickle-shaped when the oxygen concentration is low. Lack of O2 results all of the symptoms