Recent Uses of DNA Technology Essays

DNA was only gaining momentum in 1980, when Sir Alec Jeffreys discovered something that would change our world, DNA Profiling. DNA profiling is the use or extraction of human cells to be profiled. Whether they are fresh or dried-out, the cells can be tested. (Suzanne Elvidge, “Forensic Cases: Colin Pitchfork, First Exoneration Through DNA”) Sir Jeffreys first started the process of discovering genomics ability to advance our society by applying this to different types of DNA. By doing so, Jeffreys discovered that there are billions of variations in DNA sequences. In fact, the human body has 10 million different sites at which one person’s DNA sequence can vary from another’s. (University of Leicester, “The Science Behind Genetic Fingerprinting”) Jeffreys’ discovery then allowed for DNA profiling to be used in the United Kingdom, where Sir Jeffreys conducted his research. With the research and testing performed in Europe, DNA profiling was now applicable in the United States. Detectives such as Joe Horgas took advantage of this

Human DNA is very similar to one another, but only about 0.1% is different from the next person. That 0.1% can tell a person’s eye color, hair color, and other physical features. DNA analyst are able to take a drop of blood, the size of a dime, and duplicate the number DNA found in that drop. With the ability to duplicate DNA, analysts can have a back-up, in the event a human error were to occur. Analyst can tell you exactly where your ancestors came from and the percentage that is still inside your DNA. DNA is a very powerful tool that can identify a murder if the individual left any blood, saliva, skin tissue, hair or semen. The education needed to be able make use of the DNA consists of a great deal of science classes.

From cases such as OJ Simpson to Chandra Levy, DNA profiling also called DNA fingerprinting or DNA typing has played a major role in the criminal justice system. The law enforcement community uses DNA profiling to rule out or identify suspects. Unlike hair microscopy, bite mark comparisons, shoe print comparisons, and firearm tool mark analysis, DNA typing has been developed through massive scientific research and has undergone meticulous scientific evaluation (Innocence Project). DNA is a foolproof method of identifying a perpetrator of a crime.

Basically, our DNA (deoxyribonucleic acid) is our genes, and every person, except for twins, are born with a different DNA profile and that is in a giant database, containing every DNA profile of every person in the world. DNA testing started in 1985 by scientist Alec Jeffreys and was first used to solve a crime a year later. Before 1985 DNA evidence could not be used in court because it wasn’t invented yet, this increased the number of wrongful convictions which would have been prevented using DNA analysis. However, DNA analysis can still be used to solve crimes that occurred prior to the invention of DNA analysis, with a sufficient amount of DNA to be analyzed of course, which is a very small amount. Only a small amount of DNA is needed to find out who it belongs to, it can be found in blood, saliva, finger residue, hair, skin, semen and more.

(c) DNA fingerprinting could be used to exonerate or to convict suspected criminals. DNA fingerprinting could also be used to build phylogenetic trees

Due to the uniqueness of DNA it has become a powerful tool in criminal investigations

Each human being has something called DNA. DNA is described as genetics and an extremely long macromolecule that is the main component of chromosomes and is the material that transfers genetic characteristics in all life forms. DNA constructs of two nucleotide strands coiled around each other in a ladder like arrangement with the sidepieces composed of alternating phosphate and deoxyribose units and the rungs composed of the purine and pyrimidine bases adenine, guanine, cytosine, and thymine. Each chromosome consist of one continuous thread-like molecule of DNA coiled tightly around proteins and contains a portion of the 6,400,000,000 basepairs that make up your DNA.

DNA forensics can also narrow down suspect pools, exonerate innocent suspects, and link crimes together if the same DNA is found at both scenes. However, without existing suspects, a DNA profile cannot direct an investigation because current knowledge of genotype-phenotype relation is too vague for DNA phenotyping. For example, a profile from a first time offender that has no match in any database may give the information that the criminal is a left handed male of medium stature with red hair and freckles. It would be impossible to interview every man who fits that description. However, with available suspects, DNA forensics has many advantages over other forms of evidence. One is the longevity of DNA. Although it will deteriorate if exposed to sunlight, it can remain intact for centuries under proper conditions (Sachs, 2004). Because DNA is so durable, investigators can reopen old cases to reexamine evidence.

DNA profiling involves testing mini-satellites one at a time which then goes on to produce an image which is much simpler than genetic fingerprinting. It provides a pattern which is unique to a particular person and is therefore suitable for forensic purposes. (Turnpenny, P et al 2005).

for criminal gain; law enforcement also benefit from the latest technology. DNA is a technology

So you ask, "How does this work to catch or release criminals?" DNA is very simple and small. Everyone has different patterns. Using certain machinery to detect a person's DNA solves these patterns. This evidence will create a future in crime scene investigation.

DNA technology and advancements in technology in general, advancements in scientific discoveries and scientists who shared

Law Enforcement keep notes on arrests that have founded people innocent of crimes, and retention of an innocent person's DNA can be charge or otherwise, seen as a invasion of that person’s privacy and civil liberties. Dr. Alec Jeffrey, a former professor at the University of Leicester laboratory, consulted with his lawyers to develop the new type of technique called DNA profiling. His technique would prove that DNA fingerprinting (profiling) can individualize evidence compared to the blood typing. DNA profiling compares 13 standard STRs to form a profile. The analysis used by the scientists, uses PCR and STRs to profile an individual. It is highly unlike that two individuals’ identical numbers of repeats for all 13 STRs, will match, which DNA fails is hardly never due to a successful match of 385 million to 1. This makes DNA profiling the most accurate tool in Forensics.

The work of these four people led to a complete restructuring of the beliefs of the scientific community regarding genetic information. Their initial word led to further work which encompassed their hypothesis of how DNA replicates itself. From this work came the modern technologies of DNA fingerprinting and sequencing.

The process of DNA fingerprinting in humans involves the replication and arrangement of extracted DNA, to create a pattern/fingerprint that is viable for comparison. This process involves the application of DNA extraction, digestion by restriction enzymes, Polymerase Chain Reaction (PCR) and gel electrophoresis. This results in a DNA profile with bands of varying widths that can be used for the comparison of genetic information. DNA extraction occurs in three stages. Firstly, a