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Relieve Depression Research Paper

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The future - putting it into practice Why is this important? Affecting 300 million people, depression is amongst the leading causes of disability in the world according to the World Health Organisation (WHO).4 Besides having significant social and functional impairments that severely impact on quality of life, patients with chronic depressive disorders experience significant morbidity and mortality from their disease.4,5 At its worst, depression can lead to suicide. Evidently, the burden of depression and mental health conditions are on the rise globally and should be taken seriously.4 Currently, there are several effective non-pharmacological, pharmacological and psychotherapeutic approaches to the clinical treatment of depression. The most common first-line and second-line pharmacological treatment methods include selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitor (SNRIs) and tricyclin antidepressants. 6-8 …show more content…

Hence this considerable proportion of patients, who do not sufficiently respond to conventional therapeutic regimes, is left with chronic and treatment-resistant depression.6-8 On top of that, the adverse effect profile of current antidepressant regimes are concerning. The commonest adverse effects reported with current antidepressant regimes such as nausea, insomnia and loss of libido is troubling. (4,13) It is not surprising that patients have issues with concordance to treatment, discontinue their medication and

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