Research Article Critique on Alzheimer's Disease

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Danisha Stewart April 18, 2012 Research Article Critique 1 NURS 4922 1. Brodaty, H., Ames, D., Snowdon, J., Woodward, M., Kirwan, J., Clarnette, R., & ... Greenspan, D. (2005). Risperidone for psychosis of Alzheimer's disease and mixed dementia: results of a double-blind, placebo-controlled trial. International Journal of Geriatric Psychiatry, 20(12), 1153-1157. 2. The purpose of this study is to evaluate the efficacy and safety of low dose risperidone in treating psychosis of Alzheimer’s disease (AD) and mixed dementia (MD) in a subset of nursing-home residents who had dementia and aggression and who were participating in a randomized placebo-controlled trail of risperidone for aggression. 3. The problem is…show more content…
e. I did not recognize any potential bias introduced by the sampling method used. The researcher states the eligible requirements to participate in the study and the results reveal the significance of the use the patients and the effectiveness. f. The sample is representative to white female patients from nursing homes or long term facilities. The population includes Australia and New Zealand. The study reflects a large number of elderly patients with moderate to severe psychosis of AD and MD. 9. About Research Ethics: a. The study was conducted in accordance with the ‘Recommendations Guiding Physicians in Biomedical Research Involving Human Subjects’ in the 1989 Declaration of Helsinki. b. Overall, I believe that the well-being of the patients were adequately considered because this study was conducted to decrease psychosis of Alzheimer’s disease and mixed dementia by using low dose risperidone for aggression. 10. About the Research Design: a. The study was designed as an experimental research by using independent and dependent variables. b. Internal validity occurs when a researcher controls all extraneous variables and the only variable influencing the results of a study is the one being manipulated by the researcher. This means that the variable the researcher intended to study is indeed the one affecting the results and not some other,
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