Research Paper On Allergen Immnotherapy

Asthma and Allergy are accepted conditions that involve both genetics and environmental bothers (contributions). Also, this type of condition is a disease striking the cells of the human body’s immune system; however, it is inflammatory response to a normally

Before I discuss what is causing the allergies I have some interesting facts for you.

Eczema, also known as atopic dermatitis, is a chronic allergic disorder that mainly involves the skin (Sears 89). As reported in, The Allergy Book, “of all the allergic disorders…eczema is the most troublesome to treat” (89). In addition, eczema care is much more than skin deep; the whole body must be healthy to minimize eczema (Sears 98). Our immune system’s response to allergens is what causes millions of us to suffer from allergic disorders (Sears 3). In addition, epidemiologic data showed that atopic children have a different intestinal flora from that of healthy ones (Ozdemir par. 4). Researchers are beginning to link the introduction of probiotics as an effective way to treat/or prevent eczema.

In the last century, changes in the Western diet have changed the intake of omega 6 fatty acids (fats from meat and vegetable oils) compared with omega-3 fatty acids (fats from fatty marine fish). Many studies show that the change of attitude in the entry omega 3 and omega 6 through diet increased the propensity to inflammatory reactions that are associated with the development of autoimmune and allergic diseases.

Allergic rhinitis” is very comnon disease affects about 5-22% from world population with about 9% of all visits to physicians” for the allergic diseases [1].

Over the last thirty to forty years, the incidence of atopic diseases has increased. Atopic diseases are considered the “classic allergic” diseases like dermatitis, allergic rhinitis (hay fever) and asthma. Atopy is considered the ability to produce IgE (Immunoglobulin E, which is a type of antibody that can be found in small amounts in the body but plays a major role in allergic diseases) in response to common environmental proteins like house dust mites, grass pollen, and food allergens. This increase in diseases led to research into what may be the cause. Genetic predisposition is a key factor in one’s susceptibility to atopic diseases. However, researchers concluded that this particular increase had occurred in too short of a time frame

This mechanism of defense is called colonization resistance (Sekirov et al. 2010). Resident microbiota and incoming pathogens compete for resources in the intestine. In a healthy intestine, normal microflora establishes mutually beneficial relations with intestinal mucosa and effectively eliminates pathogens. Inflammatory host responses triggered by virulence factors of S. Typhimurium can alter conditions in the intestine and shift the competition between protective microbiota and the incoming pathogen, which is able to survive in and profit from the altered niche (Stecher et al. 2007), whereas to intestinal microbiota host responses are unfavorable (Sekirov et al.

Asthma is the most common chronic disease found in children from developed worlds. Today, approximately ten million children in the United States alone suffer from asthma. Asthma is believed to be increasing dramatically in direct correlation with air pollutants, household chemical exposure, certain allergens, and even food additives. Extensive studies have been conducted on childhood asthma and its association to the exposure of many of these known allergens. Ubiquitous tests have examined exposure to allergens from many household pets such as dogs, cats, and even farm animals; other studies have examined allergens from things such as tobacco smoke, cockroach exposure, mold/fungi exposure, and air pollution levels. These studies have concluded that many pivotal factors play a role in sensitizing an individual to an allergen.

Some of our gut flora play a critical role in helping us digest certain things. For example, they ferment dietary fiber into short-chain fatty acids. They also play an important role in creating vitamins B and K, as well as other important chemicals, such as sterols. These play an important role in our immune function. Problems with the gut flora are known to correlate to autoimmune disease and inflammatory

S., Church, M. K., & Scadding, G. K. (2016). Allergic rhinitis: impact, diagnosis, treatment and management. Clinical Pharmacist, Retrieved March 31, 2017, from http://www.pharmaceutical-journal.com/research/review-article/allergic-rhinitis-impact-diagnosis-treatment-and-management/20201509.article#fn_1

Similarly, “Crohn's disease was more common in subjects whose first houses had a hot-water tap (odds ratio 5.0, 95% CI 1.4-17.3) and separate bathroom… ” (Gent, A. E. and M. D. Hellier. 766). Just as hygiene relates to having easily accessible water and a separate bathroom, cleaner environments are highly associated with Crohn’s disease in contrast to underdeveloped environments. Ultimately, the risk of developing Crohn’s disease is related to the degree of exposure to pathogens during the early years of maturation of the immune

The epidemiology of non-allergic rhinitis is one-third that of allergic rhinitis, which affects 7% of 20 million people in the U.S. population and is developed in individuals after 20 years of age. (Settipane, & Kaliner, 2013). The pathophysiology of non-allergic rhinitis does not involve the immune system, but is said to be heterogeneous and is widely diverse with symptoms that are triggered by other underlying chronic illnesses, certain foods, strong odors, perfume, alcohol and, weather changes (AAAAI,

As the saying goes “we are what we eat” most people have heard of the saying, but really do not think twice about it; so what you eat can cause diseases that most people do not know about. The microbes that live in the gut helps with digestion, which plays an important role in the health of the host (Clemente, Jose C., Luke K. Ursell, Laura Wegener Parfrey, and Rob Knight. "The Impact of the Gut Microbiota on Human Health: An Integrative View." Cell 148.6 (2012): 1258-270. Web. ). Because of what you eat, it can influence the diversity of the microbes and certain disease to develop because of your diet. Knowing that what you eat can impact health it can help to change how the diet is in today’s society. This is why microbes are important to

Atopic dermatitis is a chronic inflammatory skin disease that can affect all ages but mostly children. It presents with extremely dry skin and itching that leads to scratching and a lichenified rash. An inflammatory response ensues, worsening the dry skin and continuing the itch-scratch cycle. A mixed-immune response involving IgE specific to foods and/or environmental allergens and excessive T H 2 signaling has classically been thought to cause the impaired barrier function seen in atopic dermatitis.

Every year, the number of affected peoples having an allergy, most are the children increases, more families and parents are faced with the burden of risk to find a way to manage their child’s food allergy. An allergy, true or perceived, is a common clinical problem and among the most common chronic conditions worldwide. If you have an allergy, do not ignore it. A lot of people remains unknown about how their allergies develop, so the misconceptions begin. So what are the common misconceptions on allergy and what are the causes? We better make an appointment to our doctor before we conclude the reasons what, why, where, when and how