Haloperidol is a first generation antipsychotic which works in the brain and helps to balance the amount of dopamine to improve the patient's behavior, mood and thinking. It is given to patients once a month. The side effects of this drug includes: tachycardia, sleepiness, nausea, allergic reactions and drop in blood pressure. The most common side effects on both type of antipsychotics are: weight gain, movement disorders (Tardive dyskinesia), drowsiness, dry mouth, higher risks of mortality and diabetes. Tardive dyskinesia is the abnormal and involuntary movement of the face, tongue and extremities, which is caused by the use of antipsychotic medications for many years.
“The first antipsychotics were effective in controlling positive
risperidone whereas in this one there was a fixed dose to limit breach in blinding and to facilitate comparison between similar groups, also having this fixed dosage helped prevent bias because when using a titrating schedule of dosing in a randomized trial, it tends to show bias toward a desired goal. Risperidone in this study was well tolerated and there weren’t significant differences in weight gain or sedation(13). One of the main things disliked about risperidone is its tendency to increase the incidence of dyskinesia and other extrapyramidal side effects. In this study only mild and transient dyskinesias were seen in only 3 children, however that could be due to the low fixed dosage(13) of the study.
5. What is tardive dyskinesia, and how does it respond to a reduction in the dose of an antipsychotic drug? Rhythmic, repetitive sucking and smacking of the lips and thrusting of the tongue in and out; movement of arms, fingers and toes, reversal is possible if lower dose is given immediately. (Hart & Ksir, p. 173)
As the opioid epidemic continues to rise, news outlets and politicians have focused their attention on heroin and opioids. However, they continue to ignore the number one killer, fentanyl. This synthetic opioid is similar to heroin but 50-100 times more potent. In the pharmaceutical industry, fentanyl is prescribed to treat extreme pain, specifically in cancer patients.
This prevents the excessive activity of dopamine. Side effects sleepiness, dizziness, headache, dry mouth, weight gain, weakness or loss of strength, stomach upsets such as constipation, increased appetite, abnormal dreams and nightmares, faster than normal heartbeat, a drop in blood pressure, shortness of breath, blurred vision, uncontrolled movements, problems with speech, irritability, fever.
Antipsychotics are medications that physicians use to treat psychotic disorders such as Schizophrenia, Delusional disorder, Paraphrenia, and Substance-induced psychotic disorders. These disorders are characterised by the patient’s inability to make good judgments, think with a clear head, communicate effectively, relate to society, and understand reality. Antipsychotic drugs are also useful in the treatment of bipolar conditions that involve extreme cases of manic behaviour. Examples of these drugs include Thorazine and Trilafon. These drugs belong to a drug class called phenothiazines. They work by changing the actions of chemicals in the brain. The drugs can be beneficial, however, Steen et al. (2014) argue that the medicines have several harmful effects such as changes
Methaqualone, is also referred to as Disco Biscuits, Down And Dirties, Jekyll-and-Hyde, Joe Fridays, Lemmon 714, Lemons, Lennon's, Lovers, Ludes, Mandies, Mandrake, Q, Qua, Quack, Quad, Quaaludes, Soaper, Supper, Vitamin Q, The Love Drug, Wallbangers, Whore Pills, and Sopor. This list of street names for the drug goes on and on.
In 1955, antipsychotic medications were introduced to help mental disorders. These medications are usually taken orally in which help relieve symptoms for periods of days. The misuse or abuse of the medications are low. There are three generations of antipsychotic medications. The first generation is known for reducing hallucinations and delusions, but not affecting problems like disorientation or depression. An example would be chlorpromazine, brand name being Thorazine. Some negative side effects of taking the first generation drugs are Parkinson’s-like symptoms, tardive dyskinesia, and weight gain. Next, the second generation drugs minimized the outcome of the individual getting Parkinson’s-like symptoms. An example of this generation would be Clozaril. “A unique feature of Clozaril is the 1 to 2 percent chance of developing a potentially lethal blood disease called agranulocytosis” (Levinthal 282). This disease decreases white blood cells and affects the immune system. If early signs of this disease start to appear the patient will stop taking Clozaril and recover. Lastly, the third generation has shown to be the most effective on schizophrenia. Abilify is an example of this generation drug. It does not have a risk of Parkinson’s, tardive dyskinesia, or diabetes. Abilify blocks specific serotonin receptors in which prevents negative side effects from happening. These different
It is used for the treatment of major depressive disorders, autism, and obsessive-compulsive disorder etc. The common side effects may include loss of appetite, rash, and trouble sleeping. Serious side effects include mania, seizures and increased risk of suicidal behavior in people under 25. If the intake of fluoxetine is stopped suddenly, several withdrawal symptoms may be experienced such as dizziness, anxiety, and changes in sensation. It is believed to increase the serotonin activity in the
This includes bupropion (Wellbutrin), which is also a smoking cessation aid and a norepinephrine and dopamine reuptake inhibitor (NDRI), desipramine (norpramin), which is also prescribed for nerve pain, maprotiline (Ludiomil), mirtazapine (Remeron), and trazodone (Desyrel), which is also used as a sedative. The side effects of these medications are increased or decreased appetite, nausea, vomiting, indigestion, constipation, headache, dry mouth, insomnia, increased sweating, nervousness, reduced sexual desire, difficulty reaching sexual climax, and erectile dysfunction.
Attached to your discharge papers you will find a list of the medications that the doctor wants you to take at home. The prescriptions have already been sent to your pharmacy and the pharmacy will deliver them all to your home this afternoon after 4:00 PM. I will go over each of your medications with you.
Antipsychotics are generally used to treat psychosis in mental disorders. These disorders include schizophrenia and bipolar disorder (Thyssen et al., 2010). Risperidone is known as an atypical second generation antipsychotic and used in the treatment of a multitude of disorders. This medication can often challenge behavioral problems that are associated with schizophrenia, autism spectrum disorder, bipolar disorder, or attention deficit hyperactivity disorder (Schatzberg & Nemeroff, 2013). It is important for the prescriber to be aware of the side effect and any possible adverse reactions that may occur. There can be many detrimental side effects that someone may not enjoy,
Over the past year, heroin has become even more deadly as the drug is now being laced with the elephant tranquilizer carfentanil. An April 27, 2017, article in Ars Technica describes the drug as being 100 times stronger than fentanyl and 10,000 times stronger than morphine. Carfentanil is a derivative of fentanyl, and it comes in the form of a pill, a powder, or a patch on the streets. It only takes two milligrams of carfentanil, which is the same as a few grains of salt, to knock out a 2,000-pound elephant. A person ingesting this amount of carfentanil will die.
Traditional antipsychotics are good at reducing the positive symptoms, but do not reduce the negative symptoms and are classified in low-potency and high-potency which can cause many side effects like; dry mouth, tremors, weight gain, muscle tremors, stiffness, motor disturbances, parkinsonian effects, akathisia, dystonia, akinesia, tardive dyskinesia, and neuroleptic malignant syndrome.
Iloperidone, a derivative of piperidinyl-benzisoxazole is an atypical antipsychotic drug. The specific indication for the drug is alleviation of psychotic symptoms and not schizophrenia. This is a noteworthy difference from the standard indications for the recently enlisted antipsychotic drugs as these indicate a clinical condition as opposed to a symptom happening in patients who have a clinical condition (for this situation, schizophrenia). This is the approach suggested in the TGA adopted European Union (EU) rule. Iloperidone binds with high antagonistic affinity to serotonin 5-HT1A, 5-HT2A and dopamine D2 and D3 receptors and moderately interacts with dopamine D4, serotonin 5-HT6 and 5-HT7 and adrenergic α1 and α2 receptors.
Psychosis is a serious mental disorder characterized by impaired thinking and emotions which indicate that the person experiencing them has lost contact with reality and affects about 1% of the population. It is characterized by a myriad of signs and symptoms which include distortion of thinking and perception, cognitive impairments, motor abnormalities, volition and apathy, difficulties in communication and restricted affective expression. Various allopathic medicines are available in market such as chlorpromazine, fluphenazine, triflupromazine, haloperidol, trifluperidol, penfluridol, flupenthixol, clozapine, resperidone. But prolonged exposure to antipsychotic medication has been associated with side effects including extrapyramidal symptoms