Research Paper On Stevens Johnson Syndrome

Wobbler syndrome is a disease of dogs that affects their spine in the neck region and is a very important and common cause of neurologic disability in large breed dogs. Wobblers disease is classified under a degenerative or idiopathic disease. Wobbler syndrome or wobblers is the most common name used but Veterinary literature has used multiple different names to describe this condition, this is in part due to the confusion regarding the mechanisms causing it. The name most commonly used in veterinary articles is cervical spondylomyelopathy (which means a disease of the neck vertebrae affecting the spinal cord). Other common names are CVI – cervical vertebral instability, CVM – cervical vertebral malformation, CVMM – cervical vertebral malformation-malarticulation,

Williams Syndrome is a genetic disorder that happens in the fetus stage and after birth. This syndrome is caused by the deletion of 26-28 genes in chromosome 7. Symptoms include facial deformities, trouble speaking, and the narrowing of the Aorta with many more symptoms.

1. Swelling of lips and dysphasia with questionable early Stevens-Johnson syndrome. 2. Rheumatoid arthritis class 3, stage 4.

The diagnosis of Robert Jones disorder is identified in the following DSM-IV-TR. He has alcohol dependence with physiological dependence. Roberts Blood Alcohol Concentration (BAC)] was .20" and even with this he was in denial of his state. He had a plea bargain so as to avoid jail time, he was on probation and he still believed that he had no reason to be treated for alcohol dependency. He later on developed a craving for alcohol claiming that he missed his beer; at one point he thought he was sick. He then revealed that he had been drinking for a long time almost 30 years. His DSM-IV-TR diagnosis also revealed that he was sexually dysfunctional. According to Healthwise (2011), one is said to have alchohol dependance when;

Williams Syndrome(WS) is considered as a neurodevelopmental disorder, caused by a contiguous gene deletion of about 26 genes from the long arm of chromosome 7(Peoples et al., 2000). Since it had been first aware by J.C.P. Williams in 1961(Lenhoff, Wang, Greenberg & Bellugi, 1997), Williams Syndrome has drawn more attention in last 40 years. the incidence rate is approximately 1 in 2000 and diagnosed generally at 6.4 years old (Morris, Demsey, Leonard, Dilts & Blackburn, 1988). People with WS usually show a developmental delay at the early age and are affected all life long. Williams Syndrome is characterised by some abnormalities in physical, behavioural, and cognitive.

Sarah Elizabeth Johnson (age 16), is an aspiring photographer located in Knoxville, Tennessee. Sarah Elizabeth was born in South Vietnam and grew up partly in Charlotte, North Carolina. At the age of 12, Sarah came to Knoxville, Tennessee where she began taking an interest in photography. When she turned 14, she received her very first DSLR (Nikon D3300) and since then she has been taking photos wherever she goes. She is passionate about what she does and hopes that she can inspire others through her work. - 1 Peter

Johnson-Munson syndrome is a rare syndrome identified by missing abnormal vertebrae, fingers and toes and various deformities of the heart, lungs, intestines, pancreas and intestines. Ophanet a consortium of European partners defines a condition as rare. In the US population, less than 200,000 people can possibly be affected by Johnson Munson Syndrome or second type of Johnson Munson syndrome. (Orphanet 2015)

SJS and TEN are severe mucocutaneous reactions, most commonly triggered by medications, characterized by extensive necrosis and detachment of the epidermis. The two conditions are distinguished based on severity, which is scaled by evaluating the percentage of body surface area involved in the blisters and erosions. SJS is the less severe and more common condition with 30% of the body surface with mucous membranes involved in the majority of cases. The mucous membranes were not involved in this patient making SJS and TEN less likely. However, the mortality rate for SJS is 10% and TEN is 30%, which is why it was important to rule out these conditions before sending the patient home. Although SJS and TEN are usually triggered by medications, one study showed that approximately 20-25% of pediatric cases could not be clearly attributed to a drug. While this patient’s history does not indicate any new medications, we cannot simply rule out the possibility of SJS or TEN for that

The exact, underlying mechanisms that lead to the symptoms of SJS are not completely understood. It is unknown how individual drugs specifically cause the symptoms of the disorder. Researchers believe that the immune system intervenes in the process of breaking down the drug to which the body is reacting. The improper immune response against the drug results in damage to healthy cells of the body. Keratinocytes, which are the precursor cells that develop into skin cells, are affected in these disorders and are destroyed during the disease process.

These symptom then develop into a painful purple or even a reddish rash. The rash leads to blisters, that leads to the top layer of your skin to shed. Having the skin be exposed like this, can lead to more serious infections. It can also lead to blindness, damage to internal organs, permanent skin damage, and death. Toxic Epidermal Necrolysis is similar to the Stevens-Johnson Syndrome, in which it also has flu-like symptoms, then develops into a blistering rash. Skin peels off, nails and hair even began to fall out. It is fatal when the person becomes infected. The third skin reaction is the Acute Generalized Exanthematous Pustulosis. This reaction causes many small blisters to show up on the skin, along with a fever. This condition usually settles in about two weeks, but only if the acetaminophen is

Stevens-Johnson Syndrome (SJS): is a life threatening reaction. Many manifestations are involved such as detachment of the epidermis, acute blisters, erosion, severe purulent conjunctivitis, stomatitis and purpura macules. The main etiology is medications. Usually started  as a high fever and flu-like symptoms followed by mucocutaneous symptoms. SJS patients are managed like a burn patient.

Ever since I was a little girl, I have always wondered why God chose to give me the diseases I have. Did I do something wrong? Did my parents do something wrong? I felt as though God had turned on me and deserted me, and no matter how many times my mom told me that God has a plan for everyone, it never really made sense. I still constantly wondered if maybe God was mad at me or was maybe punishing me for something out of my control. It was not until I met Anyaa that I realized that God did not give me a challenge by giving me these permanent diseases, but he really granted me a gift.

Sjögren’s Syndrome is an autoimmune disease that affects the whole body. Symptoms of SS include extensive dryness, fatigue, chronic pain, dysfunction of organs such as kidneys, blood vessels, lungs, liver, etc, neuropathies, and lymphomas. SS can occur in the presence of another autoimmune disease such as rheumatoid arthritis, lupus, or scleroderma. Symptoms can vary from mild to debilitating, and SS can remain steady, worsen, or, although rare, can go into remission. Today, at least four million people are living with this disease in the United States.

Turner Syndrome is a genetic disorder that effects a girl’s development. Girls who have it are short, and most are infertile. Girls and women that have turner syndrome are at a risk for many health problems, including high blood pressure, kidney problems and diabetes. There is no cure. But treatment can help reduce symptoms as you read in the text below. This information stated below will explain health issues of turner syndrome. It will also cover symptoms and causes of this disease as well as diagnosis and treatment options.

Allan-Herndon-Dudley syndrome (AHDS) is a rare disorder of brain development that causes severe intellectual disabilities and problems with locomotion. AHDS occurs exclusively in males disrupting development from before birth being a psychomotor retardation characterized by neurological impairment and abnormal thyroid hormone (TH) levels. Past research has shown that mutations in the TH transporter monocarboxylate transporter 8 (MCT8) are associated with AHDS with MCT8 knockout mice exhibiting impaired TH levels but lacking neurological defects. However the Zebrafish mct8 gene and promoter were isolated and promoter-driven transgenic lines were constructed to resolve that mct8 is primarily expressed in the vascular and nervous system similar