Research Proposal : Melanoma Skin Cancer

     Distinguishing melanoma may seem hard to do, but is not so once a person is informed on what they should be looking for. They may appear similar to moles, and may be blue or black in color. Though they will usually lack the symmetry and border regularity of a common mole, and may have variance in their coloring. Melanomas can either appear suddenly, or develop slowly near a preexisting mole. In rare cases, melanomas may form on top of previously formed moles or birthmarks, but will also come with the effects of pain, itching, or bleeding. These moles may begin to exhibit new and/or strange characteristics such as

It develops in the melanocytes, which are cells that produce melanin that gives the skin its pigment or color and protects tissues from ultra violet radiation. Dark skinned people have more melanin than light skinned people do. For this reason, Melanomia is more frequent in light skinned people. (“Detailed description “, 2000, P.2

Any type of change size, color, or shape of a mole is an important warning sign. For weeks or months, watch the changes that occur. The ABCDE rule is a helpful rule to estimate skin changes. A is asymmetry. If one half of a mole does not match the other have there is no symmetry. B is border irregularity. Jagged, uneven, or blurred edges of a mole should catch your attention. C is color. Changes in the mole color, particularly from the edge of the mole to the middle. D is for the diameter. If the mole is larger than 6mm the mole should be of concern. E is evolution. Changes in the surface size and shape, as well as itching or tenderness should be observed. Often time’s melanoma is developed in unmarked skin, but can also develop in existing moles or birthmarks (“Melanoma and Skin Cancer Symptoms”). Skin examinations should be an often routine provided by a doctor. Any notice of suspicious signs, see a health care provider as quick as possible. Examinations by a dermatologist are a potential way to see if you have developed skin cancer. If during the examination skin cancer is suspected a biopsy will probably be the next process (Knight).

Unlike other cancers which we can develop, melanoma can often be detected on the skin which allows doctors to treat it at its early stages resulting in less complications and lower death rates to patients, again if left undetected at its early stages this can easily spread to distant areas and distant organs. Once melanoma has spread to other areas of the body which is classified as stage IV it is diagnosed as

Although there are several types of skin cancer, the most aggressive form is melanoma. This cancer of the skin involves mass replication of the pigment producing melanocyte cells, which are located in the epidermis, below the basal layer. There are several factors involved with the onset of melanoma including, exposure to ultraviolet rays, genetic predisposition, numerous nevi (moles), immunosuppression, and environmental exposure to carcinogens.

Melanoma is the most dangerous type of skin cancer. It develops when unrepaired DNA damage to your skin cells trigger genetic defects that lead you skin cells to multiply at a fast pace and form tumors. Melanoma can often resemble moles and some can come from previous moles. These melanoma moles can range in color from pink, red, brown, purple, white, blue and skin-colored, but more mostly seen as black or brown. It’s said that consumers who use indoor ultraviolent tanning devices are seven-four percent more likely to develop melanoma compared to someone who has never used a tanning bed before. Melanoma is usually caused from intense and over exposure to UV radiation. It has be estimated to kill around 10,000 individuals in the U.S. each year. The lifetime risk of melanoma is 1.5 times higher in males than in females. Melanoma is curable, if it is recognized early and

Surprisingly, the sun-kissed tanned skin is what most younger whiter complexions are eagerly trying to desire; despite the risk of artificial tanning that could cause to a person’s health, but the rate of people using a tanning salon is still rising. In America, there are 30 million white females from ages 16 to 29 years old that are fascinated in indoor tanning (Becirevic, Amel et al, 2017). As the rate of tanning bed users rises the melanoma incident has also increased. Melanoma risk is associated with artificial tanning for a very long period of exposure to the ultraviolet radiation which skin problem can occur later in life. People used artificial tanning as it gives very quick result for a brief period and the fewest number of sessions

According to Mays and Tercyak (2015), “An estimated 9,000 deaths occur each year as a result of melanoma, and the costs of skin cancer treatment results in $8 billion annually (p. e70). The major concern for preventing skin cancer from resulting is due to indoor tanning salons (Mays & Tercyak, 2015). Most skin cancer cases are associated with indoor tanning salons (Mays & Tercyak, 2015). Young adults seem to know the risk of indoor tanning, but still do not protect themselves from the dangerous behavior (Hemrich et al., 2014). Even when young adults have family diagnosed with skin cancer, they still continue to tan and do not participate in safe skin-care prevention (Hemrich et al., 2014).

It is usually caused by intense exposure from ultraviolet radiation such as sun or tanning beds. Melanoma is when damaged DNA from this high exposure triggers mutations in the body that leads to the intense multiplication of cancerous cells. Melanoma cancer can look almost like a mole and can range from skin colored to black or brown in color. If caught and treated early it is curable, however if not caught early it can spread into the body and cause other cancerous cells or death. There are four types of melanoma skin cancers: superficial spreading melanoma, lentigo maligna, acral lentiginous melanoma and nodular melanoma. Superficial spreading melanoma is the most common and is usually seen in young people, but in all ages as well. It is known for growing along the epidermis for a long period of time before penetrating into the skin. This can also be found almost anywhere on the body but usually for men on their upper bodies and for females on their legs but also upper bodies. Lentigo maligna is known for its appearance for can look similar to a tan or dark discoloration. It is usually found in the elderly population and is the most common in areas of Hawaii. It is found on the upper body, arms, facial area and ears. Acral lentiginous melanoma is known for its appearance under the nails, palms of the hands or feet as a dark discoloration. It is mostly common in Asian and African-American cultures and can

Melanoma being the austere form of skin cancer which can be fatal in most cases. Mayo Clinic’s article on the diseases and conditions of melanoma gives good clarity as to what is actually occurring, and how it forms. The article states that what causes melanoma is unclear and hasn’t been discovered but what takes place is the melanocytes that generate melanin cells is agitated by unknown causes which results in the change in pigmentation of the skin or a change in a current mole already present on the skin. Strategies that can help you detect the symptoms of melanoma consist of the letters “A- E meaning A: asymmetrical shape regarding moles, B: irregular boarders, C: change in color, D: diameter, and E: evolving” (Mayo Clinic Staff 2016) Melanoma can appear not only on the skin but underneath a person’s nail, it can affect their eyesight and rarely their internal organs such as the mouth, urinary tract, and digestive tract called mucosal melanoma. These are noted to be hidden

Melinoma grows vry quickly and it can become life threatning as a matter of six weeks if this is untreated by a doctor. Sometimes it can appear on our skin that is not exposed to sunlight. For this cancer it can appear to be flat smudgy outlined,it can alsombe more than onen color like black, red, grey, blue, or even brown. The ways that you can lookfor this cancer is to look for spots that are not round (asymetrical), spot that are uneven boarders on you skin, unusaual or uneven

The care of patients who have cutaneous melanoma (CM) has undergone a dramatic shift during the past 5 decades. Excision of pre-metastatic; CM has been the overriding goal. because once distant metastases have occurred. prognosis is dismal. Skin awareness and self-examination by patients. screening examinations of the skin, nails, and mucous membranes by physicians, and careful long-term Surveillance of patients determined in be al high risk for CM 'based on identifiable historic and phenotypic traits are having an immediate positive impact on CM. related mortality and CM-related case. fatality rate.

The most common sign of melanoma is the appearance of a new mole or a change in an existing mole. This type of mole can appear anywhere but most often on the back, legs, arms and face.

Melanoma is a malignant tumor that arises from pigment-producing skin cells termed melanocytes. When the cell division of these melanocytes becomes unregulated, they begin to divide and multiply too rapidly. This results in a cancerous overgrowth of these pigmented cells. Melanomas most frequently begin as a benign mole or freckle, which subsequently grow and transform into cancerous lesions. The most lethal type of skin cancer, melanoma is often a direct result of exposure to ultraviolet radiation from the sun (Ignatavicius, 2016).

Thesis: Skin cancer is the most common type of cancer in the United States but is highly curable if detected early and treated properly.