Resveratrol, Heart Disease And Alzheimer's Disease

What is dementia? Dementia a neurologic condition characterized by the following cognitive defects; impaired memory, disturbed intellectual function, and inability to solve a problem (deWit O’Neill 2014). Dementia occurs in different stages in this paper we are going to be discussing late stage dementia, and the end stage. The effect that dementia has on a person’s nutritional status. Why is the dementia patient more at risk for malnutrition? Things we as health care providers can do to improve the person with dementias intake, and preventing malnutrition, and finally how nutrition effects the dementia patient during the final and end stages.

According to data available from the Alzheimer’s foundation every 67 seconds someone develops Alzheimer’s disease and currently at least 5.3 million people are affected by the disease. The numbers are expected to grow as 75 million baby boomers transition into retirement by 2030. Alzheimer disease is a brain disorder that causes decay and dis- function of neurons resulting in memory loss, speech and language impairment. This can also extend to challenges in physical and social behavioural. The brain, consisting of the cerebrum, cerebellum and brain stem is the primary target of Alzheimer’s disease. At three pounds the brain has a network of arteries and a folded cortex that is responsible for memory and movement. These functions are facilitated by a network of neurons. Alzheimer’s disease interferes with these neurons by disrupting electrical transfer; Death of brain cells is inevitable as the cortex shrinks becoming incapable of developing thoughts and memory. The Alzheimer’s patient experiences an altered personality with family members becoming strangers.

Alzheimer’s, the most relevant cause of Dementia, is a disease that affects as many as 4.5 million Americans per year (WebMD 2005-2014). Alzheimer’s is a disease that is an irremediable, continuous brain neuron degenerative disease that can be asymptomatic at first and then overtime becomes symptomatic. Alzheimer’s is a gradual disease that advances in three phases: mild, then moderate, and, finally, severe (1). Symptoms appear after the age of 60 and include: the slow destruction of memory and thought processes, and ultimately ends with the absent ability to do normal everyday duties. These symptoms can be anything from forgetting a recent event, or can be as problematic as forgetting the name of a family member. There are many daily

Dementia is a disease that is seen to be affecting many of our elderly population nowadays. Dementia patients show progressive symptoms, which become severe with age. Some of the symptoms include memory loss, difficulty performing intellectual activities and overall lose of cognition. There are many causes of dementia so therefore the prevalence rate of it is increasing yearly. Dementia can be caused due to genetic vulnerability such as Alzheimer’s disease (AD), lifestyle choices and from other chronic disorders, which increase your risk of getting dementia. Alzheimer’s disease and vascular dementia are the two most prevalent forms of dementia (ref). Dementia is also sometimes related to other genetic disorders such as Parkinson’s disease

“Dementia is characterized by chronic, global, non-reversible deterioration in memory, executive function, and personality. Speech and motor functions may also be impaired” (Butler and Radhakrishnan, 2011). As defined by Butler and Radharkrishnan, dementia is a disease that affects a person for their whole life. In the next part of this paper, I’m going to talk about the dementia and the effects it has on a person live whether it is with the symptoms, overall experience with it, and what exactly it does to the body. Dementia isn’t a fun disease to have or deal with. According to the World of Health Organization, over 35 million people have dementia (Robitaille, Garcia, & McIntosh, 2015). I’m mainly going to talk about the specific type of dementia Alzheimer’s. “Alzheimer’s disease is defined as a type of dementia characterized by an onset and slow deterioration, and involves impairments in memory, speech, personality, and executive function”(Butler and Radharkrishnan, 2011). Memory loss isn’t just the only thing that happens with dementia. They also experience impairments in language, communication, focus, and reasoning (Ellis, 2013).

Resveratrol is an antioxidant that certain plants produce to shield against stress from the environment. People ingest small amounts when they eat red grapes, red wine, berries or dark chocolate.

Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the most widespread age-related neurodegenerative diseases. Both diseases impact a considerable number of people, where AD occurs in around 10 percent of the population greater than the age of 65 while PD occurs in roughly 1 percent of the population above the age of 65. AD is considered to be the most widespread cause of dementia, characterised by the progressive memory and cognitive deficits which impair ones day to day activities. The pathological hallmark of AD comprises of extracellular accumulation of senile plaques consisting of mainly amyloid-beta (Aβ) peptides, along with neurofibrillary tangles which are composed of the phosphorylated tau protein, located in the hippocampus and cortex. Conversely, PD is considered to be the most widespread movement disorder that is characterised by symptoms such as rigidity slow movements, resting tremor and other instabilities. The extreme loss of dopaminergic neurones in the substantia nigra is what defines PD, as the loss of this nerve cell can be linked to Lewy bodies containing aggregates of a soluble protein called α-synuclein.

We’ve all heard of it. We’ve read articles about it and seen it on movies such as “The Notebook.” Most of us have family members or friends who suffer from it. So why is it that most individuals still don’t know what it is? According to the Alzheimer’s association, over five million Americans are living with Alzheimer’s disease. It is also noted that Alzheimer’s disease is the sixth leading cause of death in the US, causing more fatalities than breast and prostate cancer patients combined. With that being said, how many commercials have you seen about Alzheimer’s awareness? How many 5k’s and walk-a-thons have you seen advertised opposed to cancer awareness? My purpose with this paper is to shed light on Alzheimer’s and dementia disease and

Dementia is a chronic illness that effects millions of Americans annually with increasing numbers. The general understanding of dementia is that it affects the mind, and while it does affect the mind, entangles much more than just that. Dementia engulfs a patient 's mind, family, a level of caregiving, and an involvement in research of the disease.

My great grandmother suffered from Early- onset Alzheimer’s Disease, Parkinson’s Disease, and Diabetes. As a child, I remember always watching her keep an eye on her insulin levels, having a hard time holding things because her hands shook too much, and eventually forgetting most of the conversations we had. Now being able to understand why or how these diseases are brought up really caught my attention throughout this chapter. Prior to reading the chapter, I had never given much thought to the fact that Alzheimer’s, Parkinson’s and Diabetes all seem to have created issues in my family’s past.

Resveratrol (3,4 ',5-trihydroxystilbene) is a naturally occurring phytochemical present in red wine, grapes, berries, chocolate and peanuts. Clinically, resveratrol has exhibited significant antioxidant, anti-inflammatory, anti-viral, and anti-cancer properties. Although resveratrol was first isolated in 1940, it was not until the last decade that it was recognised for its potential therapeutic role in reducing the risk of neurodegeneration, and Alzheimer 's disease (AD) in particular. AD is the primary cause of progressive dementia. Resveratrol has demonstrated neuroprotective effects in several in vitro and in vivo models of AD. Apart from its potent antioxidant and anti-inflammatory roles, evidence suggests that resveratrol also facilitates non-amyloidogenic breakdown of the amyloid precursor protein (APP), and promotes removal of neurotoxic amyloid beta (Aβ) peptides, a critical step in preventing and slowing down AD pathology. Resveratrol also reduces damage to neuronal cells via a variety of additional mechanisms, most notably is the activation of NAD+-dependent histone deacetylases enzymes, termed sirtuins. However in spite of the considerable advances in clarifying the mechanism of action of resveratrol, it is unlikely to be effective as monotherapy in AD due to its poor bioavailability, biotransformation, and requisite synergism with other dietary factors. This review summarizes the relevance of resveratrol in the pathophysiology of AD. It also highlights

The main objective of the research was to examine the relationship between resveratrol, a substance that is extracted from plants and found in certain foods, and the delayed development of Alzheimer’s disease.

Alzheimer's disease is a slow progressive disease, and no known treatment can stop this progression. Knowing you will get this disease allows for early planning for the future. I would want to make sure my wishes for where I would live, and who would take care of me, could be voiced before these decisions would have to be made for me. Also, once the symptoms of Alzheimer’s start to become more severe, holding a career becomes more difficult. Finances would have to be planned so that my treatments and care could be paid for without any strain on my family. If I decided not to get tested and later on got diagnosed it would be much harder on myself and my family to deal with these situations in such a short amount of time. One of the biggest

I looked away as the syringe needle slowly pierced into his wrinkled skin. I could sense the sting just by looking at his facial expression. This is the daily routine for my paternal grandfather who is living with type two diabetes. As I continued to observe him, I noticed his blank stare towards the empty ceiling. It was another sign that he was in a different place as he also suffers from Alzheimer's. While my grandfather suffers from diabetes and Alzheimer's, my maternal grandmother has been diagnosed with Lyme disease and early stages of dementia. In both cases, I was in a predicament where I was incapable of aiding either grandparent. However, after visiting my grandfather in the hospital this past summer, I witnessed a staff of nurses

Living to be an old age is what most dream of. Living to an old age allows people to live their lives to the fullest, make mistakes fix them and grow from them. For those who have children and live a long life get to enjoy watching their children grown up and have children of their own. They then get to see their grandchildren grow up and teach them life lessons that they have learned. People who grow to see old age have to worry about dementia, and the most common cause of dementia Alzheimer’s disease. It is can have a toll on the person and their family. Those who once was head of the family is now dependent and no longer have the freedom they once had. They are also subject to falls due to lack of muscular use and loss of bone density.