Review Of Literature : Classification Of Antifungal Drugs

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Review of Literature REVIEW OF LITERATURE Classification of antifungal drugs: Barar (2000) reported that, the antifungal drugs may be classified as: 1- Antifungal antibiotics: • Griseofulvin. • Polyenes (Nystatin,Natamycin,Hamycin and Amphotericin B). 2-Synthetic antifungal agents: • Flucytosine,Cotrimoxazole,Dapsone,Haloprogin,Imidazoles, Clotrimazole, Miconazole, Econazole, Ketoconazole, Isoconazole, Sulconazole and Tioconazole. • Triazoles: Fluconazole and Itraconazole. 3-Miscellaneous antifungal agents: • Hydroxystilbamidine, Potassium iodide, Tolnaftate, Undecylenic acid, Clioqinol, Terbinafine, Ciclopirox olamine, Triacetin, Benzoic and Salicylic acid. Abuhammour and Habte-Gabr (2001) reported that, fungal infections have been classified into two distinctive classes: systemic and superficial. Consequently antifungal agents are classified under two major headings, systemic and topical agents .There are only a few systemic antifungal drugs available for use and these are polyenes (Amphotericin B), pyrimidines (Flucytosine), azoles (Ketoconazole,Fluconazole and Itraconazole) and Griseofulvin. Brenner and Stevens (2006) recorded that, antifungal drugs are classified as: • Polyene antibiotics(Amphotericin B,Natamycin and Nystatin). • Azole derivatives(Clotrimazole,Econazole, Ketoconazole, Voriconazole, Fluconazole and Itraconazole). • Allylamine drugs(Naftifine and Terbinafine). • Other antifungal drugs (Caspofungin, Ciclopirox,

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