Rheumatoid Arthritis And Its Effects Essay

Rheumatoid arthritis is a systemic disease that affects whole systems of body particularly cardiovascular system, nerves, respiratory system (RACGP, 2009). The causes of rheumatoid arthritis are unknown but it is hereditary which assists to have a risk of rheumatoid arthritis by 50%-60% (RACGP, 2009).

As I began my sophomore year of high school, I envisioned another year full of sports and normal high school activities. I was looking forward to playing basketball as I had done in my freshman year. A few weeks into the new school year I slowly realized that vision would not play out how I thought it would. When I began to notice a nagging pain in my hands and fingers that would not go away, I knew something was wrong. Basketball, a sport that I had once loved to play became almost impossible for my swollen hands to handle. The pain progressively got worse and eventually spread throughout my body, making it difficult to walk and carry out simple tasks. After two long months of tests and several doctors, I was finally diagnosed with Rheumatoid Arthritis.

Rheumatiod arthritis affects three times more women than men. It strikes people of all ages, though generally those of middle- age or older. Rheumatoid arthritis is an inconsistent disease. In some people, it leaves after a few months or years without leaving any noticeable damage. In other people, the symptoms persist and cause the person to be unable to function.

Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small

Rheumatoid Arthritis or (RA) is an autoimmune disease that attacks the joints and connective tissue. The result is inflammation that produces permanent damage in the joints. Rheumatoid arthritis is a chronic syndrome that tends to be progressive and destructive as compared to Osteoarthritis or (OA), which is more of an age related disease caused by “wear and tear” of the joints. In contrast to (OA), rheumatoid arthritis is characterized by inflammation mostly of the joints, but is a general body disease.

Rheumatoid arthritis is a chronic autoimmune disease that is characterised by the inflammation of the joints, often accompanied by deformities. Moreover, rheumatoid arthritis is a gradual condition, developing over several months and years. Furthermore, diagnosis of rheumatoid arthritis the moment its symptoms appear is vital for its treatment and prevention. Considering the fact that rheumatoid arthritis has no exact cause and no known cure, many people are participating in rheumatoid arthritis clinical trials.

Although, symptoms and severity of rheumatoid arthritis (RA) vary from person to person. Patient prognosis will depend on many factors, such as whether patients test positive or negative for the protein called rheumatoid factor (RF). Other factors that affect prognosis include patient’s age at time of diagnosis, overall health, and whether or not a person develop complications. Therefore, making the right lifestyle choices and adhering to the treatment plan can make a traumatic differences. (Johns Hopkin

Arthritis is inflammation of your joints. Most symptoms include pain, stiffness aching, and swelling in or around the joints. Various forms of arthritis, such as rheumatoid arthritis and lupus, can affect most organs and cause extensive symptoms. The term arthritis includes countless rheumatic diseases and conditions. Rheumatoid arthritis is an autoimmune disorder that targets the lining of joints. It transpires when the protective cartilage on the ends of the bones wears down over time. The most common type of arthritis is osteoarthritis. Osteoarthritis is the tissue that covers the ends of bones where they form a joint. While osteoarthritis can damage any joint in the body, it typically affects joints in the spine, hands, knees and hips.

Rheumatoid Arthritis is a disease that affects some 2 million people in the United States, roughly 1 to 2% of the population. It continues to be a mystery to many that study its origin. Rheumatoid Arthritis is commonly referred to as RA. It does not discriminate, it can wreak havoc on a wide range of people. It doesn’t care what your skin color is or where you reside or even your age. It is most common in people between the age of 40 and 60, but has been diagnosed in children as well. RA does seem to affect women more so than men. Some people say women are 3 times more likely to have it than men. This research paper examines Rheumatoid Arthritis in regards to: potential causes, its symptoms, how it is diagnosed, and how people cope/live with it. RA is being studied around the world, various trails and experiments continue to test new developments. Some people experience symptoms like joint stiffness at a very young age. Not everyone that has RA experiences the same symptoms. Treatment can be so different from one Rheumatologist to another. Based on this research there is still quite a bit to learn about RA.

There are several different differential diagnoses this 64 year-old female could have developed. Her occupation of working as a factory worker possible required frequent use of her hands. Examining conditions related to this type of history is important. Your differential diagnoses included some different types of arthritis. They are several different kinds of arthritis that can affect an individual. According to Marshal et al. (2014), the clinical findings should be supported with digital photography that uses radiographic technology. Osteoarthritis is a type that many people suffer from daily. It is a painful disorder that affects the joints. People often complain of pain, aching, and stiffness in their fingers, hips, and knees. Many times

Firth, J. (2011). "Rheumatoid arthritis: diagnosis and multidisciplinary management." British Journal of Nursing 20(18): 1179-1185.

The pathophysiology of Rheumatoid Arthritis or RA includes cartilage damage. The cartilage damage results in; neutrophils and cells in the synovial fluid being activated and the surface layer of articular cartilage degraded, cytokines and tumor necrosis factor alpha result chondrocytes to attack cartilage, and the synovium. The phagocytes of inflammation ingest immune complexes and degrade synovial tissue and articular cartilage. In addition, the immune systems B and T lymphocytes are activated. The B lymphocytes produce more RFs and the T lymphocytes produce enzymes that amplify and perpetuate the inflammatory response. There is a large supply of the targeted self-antigens that perpetuate the inflammatory response and formation of immune complexes. Both the

The 2015 ACR guideline has mentioned about recommendations for managing RA in patients with high-risk comorbidities such as cancer, congestive heart failure, hepatitis B, hepatitis C, lymphoproliferative disorders, and serious infections (Singh et al., 2017). The recommendation is summarized in table 3 below.

Creative Biolabs offers the most comprehensive pre-clinical animal testing services for Rheumatoid Arthritis, which includes developing animal models of Rheumatoid Arthritis and lead drug candidates’ toxicity and efficacy evolutions in various species, even in highly challenging NHP. Our experts and scientists has plenty of experience in Rheumatoid Arthritis research and they would work closely with you on every step to choose and develop the most appropriate study plan for Rheumatoid Arthritis. We also provide preclinical service for Rheumatoid Arthritis studies, such as evaluation of RA based on the immunohistochemistry, and assessment of major immune factors such as IL-1, TNF-α, IL-10.