Risk Factors Affecting Coronary Artery Bypass Graft Surgery

There are other risk factors that affect a person’s chances of developing coronary artery disease such as obesity, high blood pressure (hypertension), diabetes, lack of regular exercise, high-fat diet, and emotional stress. These other risk factors are preventable and can be changed with daily exercise, eating healthy options, and making healthy daily choices for your heart and body.

This chronic disease is also known as atherosclerosis and is characterized as a fatty plaque build-up in arteries which blocks the blood flow to the vital organs in ours bodies; with the heart being the main target. This potentially life-threatening blockage results in starvation and deprivation of oxygen enriched blood and vital nutrients that are necessary for the heart to maintain proper function; and that is being able to pump blood efficiently. Typically, it is said that the process of heart disease may begin during childhood years of an individual’s life. In a healthy individual; our arteries start out smooth and elastic, allowing effortless blood flow to our hearts and throughout our bodies. As this cholesterol-laden plaque begin to accumulate within the walls of blood vessels (which may be caused by a poor diet, and lack of physical activity, or simply hereditary) the vessels become inflamed. With the body’s effort in healing itself, this destructing plaque begins to release substances such as lipoprotenins, calcium, and inflammatory cells throughout the bloodstream.

“The patient is Adam Rudd, a 78 y/o white male with a history of hypertension. He has been diagnosed with hypertension past 15 years and is on anti-hypertensive medications and aspirin. He is very weak and short of breath. He is accompanied with his longtime friend Jennifer, who reports that Rudd was looking very weak and was complaining of severe headache and blurred vision before coming to the hospital. He is 5’9” and weighs 270 lb. Vital signs recorded were: oral temperature 98.20 F, BP 224/120 mm Hg with a heart rate of 102 beats/minute and respiration of 24 breaths per minute. The pulse oximetry reading was 94% on room air. He is complaining of severe headache and blurred vision. Rudd said that he did not take his antihypertensive medication or aspirin since he ran out of pills. He has not been taking his medication for past 15 days. He reports no known allergies to any medications or other substances.”

As mentioned, the patient’s name is Joshua John Laurane. He is an African American male of 69 years with a past medical history of diabetes (Type II), hypertension, congestive heart failure, and high cholesterol. He first presented with these underlying

The pathophysiology of ACS includes the stable plaque forms get converted into unstable plaque forms.2 These unstable plaque forms have numerous thin fibrous cap cells, inflammatory cells, activated macrophages, and smooth muscle cells. Sympathetic activity increases myocardial contractility, pulse rate, blood pressure, and coronary blood flow which leads to plaque rupture or fissure. As the artery ruptures, it causes thrombus formation and ischemia in this particular artery. Depending on the condition, different thrombi could form. The unstable angina forms a small thrombus formation, NSTEMI forms a partial thrombus formation, and STEMI forms a complete and persistent thrombus. The risk factors involved in ACS are age, physical inactivity, and history of hypertension, diabetes, or angina. The signs of acute coronary syndromes are an acute heart failure, tachycardia, bradycardia, or heart blockage, and the symptoms of ACS consist of chest pain, pain in the extremities, nausea, shortness of breath, heavy

Coronary illness is the development of plaque (fat store on the inward dividers of the veins) in the coronary conduits that supply O2 rich blood to the heart muscle, the development of plaque is called atherosclerosis. After some time passes plaques may solidify therefore limiting blood stream or totally obstructing the corridor. The development of plaque is straightforwardly identified with a people way of life, normal danger elements incorporate stoutness, high blood cholesterol and diabetes. At the point when the endothelium is harmed by blood stream, the cholesterol and fats in the blood get stuck shaping plaques. This outcomes in hypertension due the heart endeavoring to supply obliged levels of blood to the body. In the event that the blood stream to the heart muscles is limited or blocked it may

The plaque restricts blood flow to the heart and deprive the heart of oxygen it needs to function properly. CAD can be chronic, which is narrowing of the coronary artery and limitation of the blood supply to part of the muscle, or it can be acute, which results from a sudden plaque that ruptures. According to Warnica (2013), rupturing of the plaque “exposes collagen and other thrombogenic material, which activates platelets and the coagulation cascade, resulting in an acute thrombus, which interrupts coronary blood flow and causes some degree of myocardial ischemia.” The major risk factors that can lead to atherosclerosis and coronary artery disease are hypertension, dyslipidemia, tobacco smoking, diabetes mellitus, obesity, sedentary lifestyle, and genetic predisposition. The risk factors present in M.T.’s life are history of angina pectoris, history of uncontrolled hypertension due to non-compliance with treatment, obesity, and stress. M.T. is overweight with 289 pounds. M.T.’s cholesterol level is high at 280mg/dl. M.T.’s stress is related to experiencing the death of his best friend and business partner from cancer. Having three teenage children who are constantly in trouble at school and a wife who recently lost her job can be a stress factor in M.T.’s

is coronary artery disease, which involves the collection of cholesterol at inflamed sections of the arteries within the heart (Wedro). These accumulations of cholesterol then harden, forming plaques which narrow the vessels and restrict blood flow to the heart.

One of the patient’s secondary diagnoses is atherosclerotic heart disease of native coronary artery without angina pectoris. He had a heart valve replacement in 2011. Atherosclerosis is a disease in which plaque made of fat, cholesterol, calcium, and other substances builds up inside the arteries. This is an issue because the plaque hardens over time and narrows the arteries, which then limits the flow of oxygenated blood to vital tissues. This condition can lead to heart attacks, strokes, and death. Coronary artery atherosclerosis is the single largest killer of both men and women in the United States (Boudi, 2016). The patient’s atherosclerosis is located in the coronary artery. This artery is one of two main blood vessels that branch off

2(529) Atherosclerosis is the main pathologic process responsible for the progression of this disease. Initiation of atherosclerosis begins with injury to the endothelial lining of the arterial wall. Platelets adhere to the injury site causing aggregation and growth factors to be released (PDGF). 4(110) An inflammatory response is then activated promoting further adhesion of platelets. Next, blood cells pick up low-density lipoprotein (LDL) turning them into non-functioning cells, or plaque. The build of plaque causes intimal hyperplasia, forming a fibrous cap, which slowly occludes the lumen of the artery. 5

Cardiovascular disease is the disease that influences the veins which incorporate veins, corridors and vessels and the heart, overall this framework is known as the cardiovascular system. This disease is confounded for the coronary illness and comprises of plentiful issues joined with a natural methodology known as atherosclerosis; when substances develop in the dividers of the conduits. Under the cardiovascular disease flag, there are coronary diseases which influence the corridors, hear musicality issues, known as arrhythmias lastly the cogenital heart defects. The World Health Organization group cardiovascular disease into inherent coronary illness, cerebrovascular disease, coronary infection, rheumatic coronary illness, peripheral arterial disease and the profound vein thrombosis and pulmonary embolism.

Factors such as smoking, high levels of cholesterol in the blood, high blood pressure, diabetes, and blood vessel inflammation can cause CHD. Controlling these risk factors can help prevent the disease. One of the biggest factors that can help prevent coronary heart disease is lifestyle changes. These changes include eating a healthy diet which consists of low sodium, no added sugars, no solid fats, and no refined grains. Also being physically active, quitting smoking, knowing your family history, lose weight if obese, and if these changes are not sufficient medications may be prescribed to help.

When examining age in relation to risk for cardiovascular disease, middle-age is for all the highest risk. Males over approximate the age of 41 and females over 47 are at the highest risk for CVD. Genetically those individuals with a family history of cardiovascular disease will also be at a higher probability for CVD then those devoid of a family history of the disease. The

The Centers for Disease Control and Prevention (CDC) reports, the cause of death to be roughly 720,000 citizens in the United States die from cardiovascular disease each year (Centers for Disease Control and Prevention, 2014.) Deaths’ relating to cardiovascular disease have slightly dropped annually since the 1980’s. Coronary artery disease is the most prevalent type of cardiovascular disease in the U.S. and it kills around 400,000 Americans annually (Murphy, Xu, Kochanek, 2013.) Statistics like these are astounding and suggest the seriousness of this epidemic we are dealing with. Determinants of one’s health are vast but vary based on each individual.

The arterial stenosis is frequently mistakenly identified. Acute ischemia can also be caused by the simultaneous development of portal hypertension or thrombosis of the Superior mesenteric vein. Identify this disease in the beginning is difficult that’s why imaging studies are very important in these cases. As time passes it was noticed that the aorta has becoming more tortuous, especially in women and those who are committed with hypertension. Thus, sometimes aorta can be seen compressing the inferior vena cava. Aorta can suffer alteration in its size, commonly aortic dilatation. Sometimes involves the full length of the vessel, including the thoracic segment, and is associated with marked lengthening of the artery, a situation defined as dolichoectasia of the aorta.