SLE Case Study

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. While inflammation of the tissue around the joints and inflammatory arthritis are characteristic features of rheumatoid arthritis, the disease can also cause inflammation and injury in other organs in the

SLE diagnosis is made on 4 findings present at the same time or in a series. 11 common findings include: malar rash, disc shaped rash, photosensitivity, oral ulcerations, nonerosive arthritis, serositits, presence of ANA, and renal, neurologic, hematologic, and immunologic disorders. The X-ray finding is also significant, because the inflammation without erosion of the joints is a key finding in SLE. Other labs (like those listed above) are used in combination to also aid in diagnosis of SLE.

(Coffey et al., 2003; Cox et al., 2001; Finn et al., 2000). These findings are correlational,

Both medical journals provide similar information about SLE dealing with genetic influence, hormones, cytokines and similar treatment. Only difference is Mechanisms of Disease Systemic Lupus Erythematosus gives information about environmental influence and A Review of Systemic Lupus Erythematosus and Current Treatment Options journal has no evidence to support any environmental influence. It gives details about the new medication, Belimumab, which was approved by Food and Drug Administration (FDA). The results are small but significant beneficial with the blockade of B-lymphocyte stimulator with an anti-BLyS antibody (Tsokos, 2011). Another new treatment option is small molecule inhibitors of kinases such as Syk and CaMK4 that are showed in the immune cells of patients with SLE (Tsokos,

The most commonly affected parts of the body are the joints, skin, lung, liver, kidney and heart. Systemic Lupus Erythematosus is more common in women than men especially woman from the age of 15-35. The cure for SLE is currently

Do you know that there is currently three types of lupus? Discoid lupus, systemic lupus erythematosus, and lupus like a disorder called destroyer made lupus. Discoid lupus remains limited to our skin and be present in the form of a rash that appears on your face, neck or scalp. The appearance of the rash may possibly be more outward on areas of the skin exposed to electromagnetic lighting. While close by stand many forms of lupus epidemics the most communal is elevated, incrusted and rosy nevertheless not irritated. SLE remains commonly extra plain than discoid lupus. Do you know Discoid lupus is a form of lupus that is be able to cause inflammation in your organs?On behalf of nearly half of our society, this can be to

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small

The following search mechanism was used: (“lupus, African Americans” [MeSH Terms] OR (“lupus” [All Fields] AND “African Americans” [All Fields]) OR (“lupus, blacks” [MeSH Terms] OR (“lupus” [All Fields] AND “blacks” [All Fields]) OR (“lupus, minorities” [MeSH Terms] OR (“lupus” [All Fields] AND “minorities” [All Fields]) OR (“SLE, African Americans” [MeSH Terms] OR (“SLE” [All Fields] AND “African Americans” [All Fields]) OR (“SLE, blacks” [MeSH Terms] OR (“SLE” [All Fields] AND “blacks” [All Fields]) OR (“SLE, minorities” [MeSH Terms] OR (“SLE” [All Fields] AND “minorities” [All Fields]) OR (“lupus, race” [MeSH Terms] OR (“lupus” [All Fields] AND “race” [All Fields]) OR (“SLE, race” [MeSH Terms] OR (“SLE” [All Fields] AND “race” [All Fields]). A total of 344 results were obtained and the title and abstract were reviewed by two of the authors (EMW and LB). The inclusion criteria were original research papers related to the prevalence and clinical course of SLE in African Americans. We excluded literature reviews, case reports, and surgical techniques articles. We also excluded papers published before 2000. In addition, a manual search of all referenced articles not found in the main search was performed. A total of 71 full papers were full reviewed, but we also excluded 38 additional papers because they were case studies or not limited to African Americans, for a total of 33 studies included

If one has or has had at least four of the preceding conditions, there is a strong chance that they may have lupus. Common symptoms of lupus as described by the Lupus.org website also include edema in the legs, feet, hands, and around the eyes, hair loss, abnormal blood clotting, Raynaud’s phenomenon, and painful or swollen joints. In a 2002 article from the journal Rheumatology about the long term complications of SLE, it is stated that although the

Systematic lupus erythematosus (SLE) is a chronic, systemic, autoimmune disease. This condition causes the body to mistaken its own tissues and organs as foreign bodies and begins attacking them causing continuing inflammation and pain. (Huether & McCance, 2012) The cause of SLE still remains unknown, but it is possible that is inherited as a complex trait or caused by environmental stimuli. (S) Anyone is at risk for Lupus, but is more common among women than men and is more prevalent of African Americans and Asians. (National Library of Medicine 2010, para 2) This condition can be difficult to diagnose, as a patient must present a number of the recognizable symptoms. Depending on the location that Lupus presents itself in the body, the symptoms

The American College of Rheumatology (ACR) and the Georgia Council on Lupus Education and Awareness (GCLEA) partnered to increase community awareness on Systemic Lupus Erythematosus (SLE) and to further educate lupus patients throughout the underserved region of southwest Georgia. Systemic Lupus Erythematosus, the most common form of lupus, is an autoimmune disease that causes the immune system to attack needed body tissues (“Lupus,” 2018). This specific type of lupus affects major functions of the body including the brain, lungs, skin, and kidneys. Lupus is commonly difficult to diagnose in humans due to its vague symptoms that mimic the symptoms of other major conditions (‘Lupus,” 2017). Presently, researchers are unaware of the origins

Makover, M. & Zieve, D. (2011, February 14). Systemic Lupus Erythematosus. National Center for Biotechnology Information. Retrieved July

Systemic Lupus Erythematosus is a chronic autoimmune disease which causes inflammation of your joints, tissues, and organs. The inflammation presents itself as heat, pain, swelling and redness. SLE is a variable disease that doesn’t take any one particular course; therefore its unpredictability makes it even more devastating. No two people will experience the same disease symptoms or severity level. As S.L.E progresses there will be periods of very subtle to no symptoms at all called remission or an exacerbation of symptoms called flares.

Thus, testing for ANA or ANA-specific autoantibodies have been incorporated in a number diagnostic criteria. For example, a positive ANA finding was incorporated as a diagnostic criterion for SLE [18, 19]. In 2013, a joint committee of the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) formulated a new set of SSc classification criteria which included the ANA-specific autoantibodies, namely; anti-topoisomerase I (anti-topo I or anti-Scl-70), anti-centromere (ACA), and anti-RNA polymerase III (anti-RNAP III [20].

B research binomial, the group in question being repeatedly tested. The incidence rate ratio or IRR can be defined as, “…a measure of the frequency with which a case occurs in a population over a period of time” (Statistical, n.d., pg. 1). The IRR is an event that takes place in a group over the course of a period. When the researchers are implementing Q25 and Q95, they are comparing it to the linear regression. They are looking at regression parameters estimates the change and response of a variable. With the confidence levels close together it shows that there is a close relationship, which shows a very close gap and that in turn means more accuracy. All of the confidence levels for this chart show a very close relationship. That means that there is more accuracy within the figures and table. Since the numbers are so close, the graph for this will very tall and tight. Also, the mean or average falls into the middle of the confidence intervals. We have to look at the 95 percent confidence interval. That means that the sample size was taken, that 95 percent of them would include the true population.