SLE Disease

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Systemic Lupus Erythematosus aka (SLE) is an autoimmune disease that occurs in most women. SLE causes the immune system to attack the bodies healthy tissues and organs and this can be very dangerous to the body depending on the severness of the disease. During this process the human body produces autoantibodies that begin to attack the body thinking as if it was foreign invaders. (This picture shows the autoactive body cells attacking healthy skin.)
Biology of the Diesease During SLE, the body’s immune system doesnt work as it should. In a healthy immune system, the body makes special proteins called antibodies and a specific type of white blood cell called lymphocytes. These two components are crucial to healthy immune system because they help to fight and destroy foreign viruses and bacteria that can be harmful to the body. In SLE the immune system produces harmful antibodies that work against the body’s healthy cells and tissues which are called autoantibodies. Autoantibodies cause inflammation in the body that could severly damage organs and tissues. Most people tend to develop an
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SLE and any other autoimmune disorders usually tend to run in families. There is no clear pattern of inheritance or genes that causes SLE, People can inherit a gene variation through things like mutation which could lowen or increase the risk of SLE, but most commonly they dont inherit this disease itself. If mutations happen (which have very low chances) then SLE can be inherited froman autosomal recessive pattern. There are other reasons that may be genetically related but are still not found. Studies showed that the Major Histocompatibility Complex on chromosome 6 (which contains the human lymphocyte antigens) was the first genetically linked chromosome to SLE. The parts in a human lymphocyte antigen include important component in the immune
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