Systemic Lupus Erythematosus aka (SLE) is an autoimmune disease that occurs in most women. SLE causes the immune system to attack the bodies healthy tissues and organs and this can be very dangerous to the body depending on the severness of the disease. During this process the human body produces autoantibodies that begin to attack the body thinking as if it was foreign invaders. (This picture shows the autoactive body cells attacking healthy skin.)
Biology of the Diesease During SLE, the body’s immune system doesnt work as it should. In a healthy immune system, the body makes special proteins called antibodies and a specific type of white blood cell called lymphocytes. These two components are crucial to healthy immune system because they help to fight and destroy foreign viruses and bacteria that can be harmful to the body. In SLE the immune system produces harmful antibodies that work against the body’s healthy cells and tissues which are called autoantibodies. Autoantibodies cause inflammation in the body that could severly damage organs and tissues. Most people tend to develop an
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SLE and any other autoimmune disorders usually tend to run in families. There is no clear pattern of inheritance or genes that causes SLE, People can inherit a gene variation through things like mutation which could lowen or increase the risk of SLE, but most commonly they dont inherit this disease itself. If mutations happen (which have very low chances) then SLE can be inherited froman autosomal recessive pattern. There are other reasons that may be genetically related but are still not found. Studies showed that the Major Histocompatibility Complex on chromosome 6 (which contains the human lymphocyte antigens) was the first genetically linked chromosome to SLE. The parts in a human lymphocyte antigen include important component in the immune
The awareness of SLE has spread exponentially during the last decade, this is observed especially for women who are getting diagnosed earlier and then move on to treatment. However,
These alien like materials are known as antigens. Having an autoimmune condition such as SLE, the body 's system may lose its ability to know the transformation among remote substances knowing as antigens and our normal cells and tissues. Our body system makes up these well-known antibodies engaged against itself. Our immune system protects our antibodies from the reaction within the body antigens to form protection and developments. The protected multiple factors build up in our tissues and can cause inflammation, injury to the normal cell, tissues, and cause pain. African American, Latino, and Asian women are more commonly affected by SLE than Caucasian women.
Lupus is a rare and crippleing disease. This disease is as rare as it is hard to undertand. Lupus being a not well known disease is hard to pinpoint. This disease causes insufferable pain and body problems. Such a terrible disease causes syptoms like swelling muscles, joint pains, general inflamations, organ failures, and overall fatigue. Lupus is an autoimmune disease ( AKA the autoimmune sytem attacking itself). This autoimmune disease is most common in youge woman in birth bearing age. With little known reason
Lupus is a chronic inflammatory disease of unknown cause that can affect virtually any part of the body. The medical term for Lupus is Systemic Lupus Erythematosus or better known as SLE. With Lupus there is a malfunction in some of the cells of the immune system. "In Lupus, the body overreacts to an unknown stimulus and makes to many antibodies, or proteins directed against body tissue. Thus, Lupus is called an autoimmune disease. ”#
The most commonly affected parts of the body are the joints, skin, lung, liver, kidney and heart. Systemic Lupus Erythematosus is more common in women than men especially woman from the age of 15-35. The cure for SLE is currently
Systemic lupus erythematosus (SLE) is a disease in which a person’s own immune system begins to recognize its own tissues and organs as foreign antigens which causes it to attack and injure those targeted structures (Perspectives 14). Discoid lupus erythematosus (DLE) causes coin-shaped lesions to appear on the skin and does not affect any other system other than the integumentary (Perspectives 23). As stated on the Mayo Clinic website the etiology of the disease is idiopathic, but it is believed that environmental factors and inherited genetic code may contribute to the formation of lupus. Lupus can also be triggered by sunlight, infections, and medications such as anti-seizure and hypertension prescriptions (Mayo Clinic). Iatrogenic cases of the disease often have their symptoms reduced or eradicated after stopping those medications (Mayo Clinic). Diagnosis of the disease is based upon criteria set in place by the American College of Rheumatology as lupus often affects the muscle and joints (Lupus.org). The list is comprised of eleven common signs and symptoms that have been observed by rheumatologists. They are: Malar or
The following search mechanism was used: (“lupus, African Americans” [MeSH Terms] OR (“lupus” [All Fields] AND “African Americans” [All Fields]) OR (“lupus, blacks” [MeSH Terms] OR (“lupus” [All Fields] AND “blacks” [All Fields]) OR (“lupus, minorities” [MeSH Terms] OR (“lupus” [All Fields] AND “minorities” [All Fields]) OR (“SLE, African Americans” [MeSH Terms] OR (“SLE” [All Fields] AND “African Americans” [All Fields]) OR (“SLE, blacks” [MeSH Terms] OR (“SLE” [All Fields] AND “blacks” [All Fields]) OR (“SLE, minorities” [MeSH Terms] OR (“SLE” [All Fields] AND “minorities” [All Fields]) OR (“lupus, race” [MeSH Terms] OR (“lupus” [All Fields] AND “race” [All Fields]) OR (“SLE, race” [MeSH Terms] OR (“SLE” [All Fields] AND “race” [All Fields]). A total of 344 results were obtained and the title and abstract were reviewed by two of the authors (EMW and LB). The inclusion criteria were original research papers related to the prevalence and clinical course of SLE in African Americans. We excluded literature reviews, case reports, and surgical techniques articles. We also excluded papers published before 2000. In addition, a manual search of all referenced articles not found in the main search was performed. A total of 71 full papers were full reviewed, but we also excluded 38 additional papers because they were case studies or not limited to African Americans, for a total of 33 studies included
Systematic lupus Erythematous (SLE or Lupus) can affect any organ in the body and may cause a wide range of symptoms. SLE symptoms can vary from person to person and can change over time. Lupus affects 1.5 million Americans and millions more worldwide lupus.org (N.d) 2016. The cause of lupus is unknown some research have found genetics and hormones are to play a role. The majorities of people with lupus 90% are female, and they seemed to develop signs and symptoms of the illness between the ages of 15 and 44 (2016). Children are affected with lupus. Approximately 5,000 to 10,000 of the million Americans with lupus are diagnosed while under the age of 18 (2016).African American women are three times more likely than Caucasian women to get lupus
Most experts can agree that there are a number of factors that cause it; the causes of Lupus are from a combination of genetics and the environment. Sometimes people inherit what is called a “genetic predisposition” which means that they inherit the chance to eventually develop it. It is very hard to pinpoint one single source of cause that triggers Lupus like I mentioned before. Things in the environment like UV rays from the sun, or unrelated things like an infection or a pregnancy can trigger it. The symptoms of Lupus range from Extreme fatigue, headaches, photosensitivity, pain/swollen joints, and one clear indicator being a butterfly-shaped rash across the cheek or nose.
Systemic Lupus Erythematosus is a chronic autoimmune disease which causes inflammation of your joints, tissues, and organs. The inflammation presents itself as heat, pain, swelling and redness. SLE is a variable disease that doesn’t take any one particular course; therefore its unpredictability makes it even more devastating. No two people will experience the same disease symptoms or severity level. As S.L.E progresses there will be periods of very subtle to no symptoms at all called remission or an exacerbation of symptoms called flares.
Systemic lupus erythematosus, or simply lupus is a chronic autoimmune disease or immune system malfunction. A person's immune system normally protects the person from viruses, bacteria and other foreign materials. When a person has an autoimmune diseases like lupus, the immune system turns against itself and attacks itself.
What causes the immune system to malfunction is unknown. Therefore, there is no reliable way to prevent developing an autoimmune disease. There is a possibility that hormones may play a part in stimulating autoimmune diseases. Autoimmune diseases may even have an inherited element because a good number of autoimmune diseases likely run in families. This means that a person is seemingly likely to develop the disease if that person has a close relative with that disease. For a few autoimmune diseases, this familial possibility remains small. (Franz, 2006, Laberge, Davidson, 2007, Schwartz, 2007, Dugdale, 2009, Wrong Diagnosis, 2000).
Lupus is a potentially life threatening disease that effects about 1.5 million Americans. Lupus can effect many different parts of the body. Lupus is a type of autoimmune system disorder in which the body cannot distinguish the difference between foreign antibodies and its own organs. So basically what happens is that the body ends up attacking its own organs thinking they are foreign substances. (The Lupus Foundation of America)
Lupus is a chronic inflammatory disease marked by its effect on various parts of the body, including the joints, skin, blood, and kidneys. It is a condition in which the body's immune system attacks its own cells and tissues, resulting in pain, inflammation, and often damage to organs. Lupus involves the immune system. The immune system makes antibodies that work to protect the body against foreign substances like viruses and bacteria. Such foreign bodies are called antigens. When a person has lupus, his or her body is unable to determine the difference between antigens and the individual's cells and body tissues. As such, the immune system creates antibodies against the individual's own tissues. These antibodies are called autoantibodies. Depending on the type of lupus, a wide range of symptoms may be experienced, from rashes, hair loss, and achy, swollen joints to fever, anemia, and abnormal blood clotting. Though the disease can affect many parts of the body, individuals usually experience symptoms in only a few organs. There is no known cure for lupus. However,
Technology is the application of scientific knowledge for practical purposes. One example of technology in the ancient world is the invention of the clock in Ancient Egypt. Ancient Egyptians were some of the first to find a way to keep time. Some forms of timekeeping involved sundials, shadow clocks, merkhets, water clocks and obelisks. Obelisks were built as far back as 3500 BCE and Egyptian sundials as far back as 1500 BCE.