Sam's Family: Sickle Cell Anemia

Sickle Cell Disease is an illness that affects people all across the globe. This paper will give a description of the sickness through the discussion of the causes, symptoms, and possible cures. Sickle Cell Disease (SCD) is a "group of inherited red blood cell disorders."(1) These disorders can have various afflictions, such as pain, damage and a low blood count--Sickle Cell Anemia.

Sickle cell anemia is a hereditary disorder that mostly affects people of African ancestry, but also occurs in other ethnic groups, including people who are of Mediterranean and Middle Eastern descent. More than 70,000 Americans have sickle cell anemia. And about 2 million Americans - and one in 12 African Americans - have sickle cell trait (this means they carry one gene for the disease, but do not have the disease itself).

Sickle cell disease is a disease that is most prevalent in people of African descent along with people of Mediterranean and Middle Eastern origin. This disease is known to affect about 70, 000 Americans and about 2 million people carry the trait (meaning that, they carry a single gene mutation).

* How is it possible for an offspring to exhibit a recessive trait if neither parent exhibited that

At the start of this experiment we were required to obtain a set of four Wisconsin Fast Plants, which are genetically, known as Brassica rapa. These plants have been, “originally selected under continuous fluorescent light to grow and reproduce quickly for research purposes, these petite, fast-growing plants have been used for teaching biology concepts” (Wisconsin Fast Plants). These four pots that contain our plants will be under our watch for the next 16 weeks where we will show our results at the end of the semester.

2. How will the alleles for these traits assort into the gametes that each parent might produce? (Hint: For a reminder on how alleles sort independently into gametes, refer to the illustration in Part 2, Question 2, in the Student Guide.)

While child 3 cannot be classified as either Mr.Johnson or Mr.Wilson’s child. When looking at the control blood samples, A blood type forms “clumps” when mixed with the A antigen, B blood type “clumps” when mixed with the B antigen, AB blood type “clumps” with both the A and B antigen, and O blood type does not “clump” with either antigen. To the right are the individuals’ sample trays. Looking at each individual’s blood samples, Mr.Johnson had A blood, Mr.Wilson had B blood, Child 1 had A blood, Child 2 had B blood, and Child 3 had O blood. This supports the claim because knowing Mrs.Johnson’s blood type is O means Mrs.Johnson has the genotype OO. Due to the individuals’ blood types it is known that Mr.Johnson has either the genotype AO or AA, Mr.Wilson has either the genotype BO or BB, Child 1 must have the genotype AO because Child 1 must have had an O trait from Mrs.Johnson, Child 2 must have the genotype BO because Child 1 must have had an O trait from Mrs.Johnson, and Child 3 must have the genotype OO because that is the only genotype for type O blood. When looking at the children’s genotypes it can be concluded that Child A must be Mr.Johnson’s child because it inherited an A trait which can only come from Mr.Johnson, Child 2 must be Mr.Wilson’s child because it had to inherit a B trait which can only come from Mr.Wilson, however Child 3 could come from either Mr.Johnson or Mr.Wilson depending on which individual has a genotype that can pass an O trait. It is not possible from this test to tell whether it is Mr.Wilson or Mr.Johnson that passed on the O trait. Every other research group agreed with our claim. Each group had come to the conclusion that Mr.Johnson was the father of one of the three children

The two recessive alleles are both on the same chromosome. Genes A and B completely follow Mendel’s principles of inheritance; genes B and C are physically connected together and never are separated from each other at any time during any cell division cycle or fertilization event. Draw below the gamete genotypes that this individual could produce.

The sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell have red blood cells that have mostly hemoglobin's, Sometimes these red blood cells become sickle-shaped or crescent shaped and have trouble going through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can get to that part of the body. Tissue that does not get a normal blood flow eventually becomes damaged. This is what causes the problems of sickle cell disease.

Sickle Cell Anemia is a hereditary disease that changes the smallest and most important components of the body. A gene causes the bone marrow in the body to make sickled shapes, when this happens; it causes the red blood cell to die faster. This is what causes Hemolytic Anemia. Older children and adults with sickle cell disease may experience a few complications, or have a pattern of ongoing problems that shorten their lives. The most common and serious complications of sickle cell disease are anemia, pain, fatigue, and organ failure. Today there are many alternatives and opportunities that a sickle cell patient may consider. One outlined in this paper is the Hydroxyurea method.

Genes come in different varieties, called alleles. Somatic cells contain two alleles for every gene, with one allele provided by each parent of an organism. Genotype refers to the information contained in an organisms DNA, or genetic material. Its phenotype is the physical

Discussion: Part A- For every albino seedling there will be three green seedlings. Being green is

Meet Henry, a man with dark hair, and Katie, a woman with gapped teeth. The couple has a child and from their physical description, we know that the child may turn out to have dark hair and gapped teeth. These simple examples are what color the fundamentals of genetics, but what if Henry and Katie have twin children. One child is a girl and she has dark hair

Parents do not transmit their physiological traits or form directly to their offspring, rather they transmit distinct information about the traits (factors), these factor later act in the offspring to produce the trait

Genes build the phenotype of humans as well as the underlying genotype. Competition between cultural genes leads to varied success of genetic determinism. It can therefore be said that learnt traits such as those espoused within a specific culture, can produce what may seem to be the genetic genotype of an individual. Genes are not always advantageous in the