Sarcopenia Research Paper

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Sarcopenia is the progressive loss of skeletal muscle mass and function with age. It often is a result of or leads to decrease in physical activity which leads to functional impairement or disability and increases vulnerability towards other chronic ailments such as cardiovascular disease, insulin resistance, type 2 diabetes etc (Roubenoff & Hughes 2000). With age there is a decline in mitochondrial biogenesis as well as reduction in the ability to promote muscle protein synthesis which has substantial impact on the age-associated loss of muscle mass and strength, both of which are the two most recognized risk phenotypes associated with sarcopenia. Previous work has reported enormous inter-individual variability in these phenotypes arising
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