Selective Breeding

Cystic fibrosis is an genetic disease that can cause bad damage to the lungs and other organs in the body. It is a common genetic (Gene) disease affecting to geriatric, (adults) young adults, or and kids. Now they’re still searching for a cure, but the only thing that is currently available is a donor’s lungs.

I support the guidelines outlined by Kitcher for the use of genetic information because of their responsible and ethical nature. I believe that future generations will benefit as a direct consequence of these guidelines. I shall begin by defining eugenics as the study of human genetics to improve inherited characteristics of the human race by the means of controlled selective breeding.

Humans have been manipulating genetic transfer for over 10,000 years since our hunter- gatherer ancestors began to settle in one place and started farming and planting crops. Those humans observed and chose organisms from natural selection to select and breed organisms that showed characteristics desired by them and this began the process of selective breeding. Selective breeding favours recessive alleles that do not persist in wild populations. Selective breeding is a process of increasing the frequency of rare and recessive alleles so that they appear in homozygous form. This has the effect of eliminating the alleles for wild type from the population and the process of domestication has become irreversible. The domestic species has become dependent on humans for their survival. It is from these domestic species that humans have selected and breed favourable genetic traits for their benefit, be it higher yield in plant crops, sweeter tasting fruit, and more milk from dairy cows or ease of handling stock, selective breeding continues to be used today.

In infants symptoms include coughing, wheezing, excess mucus in the lungs, shortness of breath, extremely salty skin and decelerated growth. With infants it is very common for them to develop pneumonia infections because of all the bacteria that resides in the lungs. With treatment, most patients with cystic fibrosis live into their 20’s and 30’s, some individuals with milder cases can live longer. Death is most often due to end-stage lung disease.Thus far no cure for the disease has been found. Although, research on gene therapy is promising. Treatment is generally aimed at alleviating symptoms, preventing infections, and slowing the progress of the disorder. (Egan’s 10th Ed,

Artificial selection – a breeder that selects desired traits for a species and then breeds that species to have those traits.

Cystic fibrosis is known to be one of the most common and deadly diseases in Caucasians, affecting 1 in 2500 children. This percentage results in 30,000 individuals within the United States to be diagnosed with CF. There are over 1900 mutations of this gene that cause a wide variety of severities within this disease. (McCance, Huether, Brashers, & Rote, 2010) Due to its complex mutation and unknown cause, only treating the symptoms of CF have been the main treatment protocol to this disease. Current treatments are cumbersome and expensive providing patients with life expectancy only into their twenties, but usually younger in most cases. There has been specific progress towards a cure involving gene therapy providing hope for a cure to

I believe that there is nothing wrong with the therapeutic gene modification when it involves somatic cells. I think that it is our moral responsibility to do what we can to help save the lives of people who are suffering. The doctors who would be proscribing the treatment have all made a hippocratic oath so it would be their moral duty to follow through on using this particular treatment. Therapeutic gene manipulation with somatic cells would break any moral, ethical, or legal laws. But the other forms of genetic manipulation are a little tricky. Therapeutic gene manipulation of germ cells can be a useful treatment of disease but its effect plays a role in a larger scope then just the patient alone. I think that it poses a greater risk to the whole of humanity of we allow changes to germ cells and future generations. It would open the door to all other types of genetic manipulation. So rules have to be put in place so no abuse of medical treatment occurs. Finally there should not be any type of enhancement gene modification occurring. I think that it will overall produce more harm then good. It is not a medical procedure that is used to help people who are suffering it would simply be a mechanism that would only play a negative role in human development, simultaneously breaking many ethical rules along the way. Genetic

After Charles Darwin published his book “On the origins of species” in 1859, evolution became a hot topic of discussion; the notion of the human race improving itself by selective breeding started to spread (Winfield, 2012). For years

possible cure for cystic fibrosis have been unable to show that “gene transfer efficiency” is

The average life span of a person with Cystic Fibrosis is 25-30 years of age. Although the more traditional treatments of this disease are adequate, is there something else that could be even better? Gene therapy is fast becoming one of the more studied aspects of genetics today. Let's take a look at some details of Cystic Fibrosis and gene therapy.

As scientists are experimenting with many methods of gene selection, the livestock industry are relying more on genetic selection. Genetic selection allow the farmers to produce the most fertile and efficient livestock. There are many impacts of genetic selection. Genetic selection allows the farmers to genetically modify the breed of the livestock to that mass production can occur to fulfill the need of consumers. With genetic selection the quantity and quality of meat and dairy production has been increased. I was not familiar with the technique of artificial insemination for reproduction biology until I took this class. I learned that artificial insemination is also a technique of genetic selection which allows the scientist to decide what kind of livestock they want. Also, to improve in fur quality of animal, the genetic selection is in used. With genetic selection, scientist can now improve the production rate of cattle. Genetic selection can also improve the physical characteristics of the livestock. To keep up with the world’s need in beef and dairy production genetic selections have a huge impact. Nowadays, the agriculture industries have been vastly improved because of the advancement in the genetic selections. Genetic selections also allow the farmer to modify animal more for either meat or dairy production. For example, Boer goat has been genetically modified to gain

Cystic fibrosis is an inherited disease that ultimately leads to death. It affects every racial group worldwide, but its prevalence varies from country to country. In those with cystic fibrosis, the lungs and digestive system are primarily affected by the disease. With the new developments in treatment and management, the 50 percent survival rate from the 1970’s has greatly improved, allowing patients to continue to live their lives longer than ever expected in the past. The new developments in prevention of exacerbations, therapy drugs and methods to preserve lung function have done great things to help patients extend their lives. Education is another important aspect of treating cystic fibrosis. For example, more the

      In the past three decades, scientists have learned how to mix and match characteristics among unrelated creatures by moving genes from one creature to another. This is called “genetic engineering.” Genetic Engineering is prematurely applied to food production. There are estimates that food output must increase by 60 percent over the next 25 years to keep up with demand. Thus, the result of scientist genetically altering plants for more consumption. The two most common methods for gene transfer are biological and electromechanical. “Early experiments all involved changing DNA using bacterial vectors”(Randerson, 2001). Through other advances scientists proclaim how they can improve the human gene pool. All humans have

Cystic Fibrosis (CF), is another disease that is taking to genetic therapy. If a corrected gene could somehow enter the cells that line the lungs, it will then start producing the critical proteins that CF patients need. This has been done, although in small quantities. These results, however, have raised hopes that sometime in the future, CF may be curable.

If a treatment is implicated before the child is born – germline gene therapy – he or she could lose all trace of that defective gene, and therefore wouldn’t pass the disease on to future generations. In somatic gene therapy, treatment is conducted when the patient is an