Selective Oxidation Of 2 Naphthol

The objective of this lab was to create a ketone through an oxidation reaction using a using a secondary alcohol and oxidizing agent in order to use that ketone in a reduction reaction with a specific reducing agent to determine the affect of that reducing agent on the diastereoselectivity of the product. In the first part of this experiment, 4-tert-butylcyclohexanol was reacted with NaOCl, an oxidizing agent, and acetic acid to form 4-tert-butylcyclohexanone. In the second part of this experiment, 4-tert-butylcyclohexanone was reacted with a reducing agent, either NaBH4 in EtOH or Al(OiPr)3 in iPrOH, to form the product 4-tert-butylcyclohexanol. 1H NMR spectroscopy was used to determine the cis:trans ratio of the OH relative to the tert-butyl group in the product formed from the reduction reaction with each reducing agent. Thin-layer chromatography was used in both the oxidation and reduction steps to ensure that each reaction ran to completion.

The carbon-carbon double bond of alkenes represents a site that has a high electron intensity. This site is susceptible to oxidation. Depending on the conditions or reagents used to initiate the oxidation of alkenes, various products can be obtained. With relative mild oxidation, it is only the pi bond of an alkene that is cleaved resulting in the production of 1,2-diols or epoxides. However, when there is more vigorous

The Purpose of this experiment is for the students to learn how to use sodium borohydride to reduce benzil to its secondary alcohol product via reduction reaction. This two-step reaction reduces aldehydes by hydrides to primary alcohols, and ketones to secondary alcohols. In order for the reaction to occur and to better control the stereochemistry and yield of the product, the metal hydride nucleophile of the reducing agents such as LiH, LiAlH4, or NaBH4 must be carefully chosen. Being that LiAlH4 and NaBH4 will not react with isolated carbon-carbon double bonds nor the double bonds from aromatic rings; the chosen compound can be reduce selectively when the nucleophile only react with

In the Cannizaro reaction an aldehyde is simultaneously reduced into its primary alcohol form and also oxidized into it 's carboxylic acid form. The purpose of this experiment is to isolate, purify and identify compounds 1 and 2 which contain 4-chlorobenzaldehyde, methanol, and aqueous potassium hydroxide. Compounds 1 and 2 are purified by crystallization. . The purified product will be characterized by IR spectroscopy and melting point.

Wine has several critical components, which create its complex aroma and flavour profile, that oxidise with air. The main oxidisable compounds in wine are phenolics, which include wine pigments. Phenolics or a phenol molecule has a benzene ring structure with a hydroxyl or alcohol functional group (OH) – directly bonded to the benzene ring.

Catechol oxidase is an enzyme that speeds up the oxidation reaction when catechol is exposed to oxygen. When the reaction occurs, benzoquinone is produced turning the oxidized substance brown. It was hypothesized that the higher the concentration of catechol oxidase, the browner the substance will turn, and the faster it will achieve the color. In the present lab, different concentrations of catechol oxidase were mixed with pure catechol and the rate at which each solution browned was measured using a colorimeter. The

Abstract: Using hypochlorous acid to convert secondary alcohol called cyclododecanol to the corresponding ketone which is cyclododecanone by oxidation.

This experiment was designed by conducting a substitution reaction to construct a complex compound (2-methylphenoxyacetic acid) from two simple parts; also known as synthesis - converting simple molecules into more complex molecules. A purification technique known as crystallization was used to purify the product. Suction filtration was used to filter out the product. The experiment was completed over a three-day experimental period.

In this laboratory experiment a synthesis was performed through several separate steps. The purpose of the experiment was to synthesize tetraphenylcyclopentadienone from benzaldehyde and to run reactions on carbonyl containing compounds. There was a total of three steps that led up to the synthesis of the final product, tetraphenylcyclopentadienone. The first step of the experiment was the condensation of benzaldehyde to yield benzoin. Thiamine catalyst along with water and ethanol were added to the benzaldehyde, then NaOH was added until the solution turned yellow. After recrystallization, the product was benzoin. Step two was the oxidation of benzoin to benzil.

The purpose of this experiment is to convert carbonyl compounds to alkenes using Wittig reaction. In this case we will be synthesizing Trans-9-(2-phenylethenyl) anthracene from benzyltriphenylphosphonium chloride and 9-anthraldehyde. We will also aim to obtaining a high percent yield and purity for the synthesis of Trans-9-(2-phenylethenyl) anthracene. The mechanism for this reaction goes thus:

In this preparative lab, an aldol (trans-p-anisalacetophenone) was produced from the reaction between p-anisaldehyde and acetophenone with the presence sodium hydroxide. The reaction also showed the importance of an enolate and the role it played in the mechanism. Sodium hydroxide acts as a catalyst in this experiment and is chosen because of its basic conditions and pH. The acetophenone carries an alpha hydrogen that has a pKa between 18 and 20. This alpha hydrogen is acidic because of its location near the carbonyl on acetophenone. When the sodium hydroxide is added, it deprotonates the hydrogen and creates an enolate ion. This deprotonation creates a nucleophilic carbon that can attack an electrophilic carbon (like a parent

The method used in this experiment is called an oxidation reaction. An oxidizing agent takes away electrons from other reactants during a redox reaction. The oxidizing agent typically takes these electrons for itself, thus gaining electrons and being reduced (Helmstein, Ph. D 2017). The organic oxidant used in this experiment is sodium hypochlorite, which is also known as “household bleach’. Sodium hypochlorite in acetic acid is an alternate oxidizing agent used for the development of ketones that was developed by Stevens, Chapman and Weller due to the many advantages it displays (J. Org. Chem, 1980, 45, 2030). This particular oxidation of sodium hypochlorite is an exothermic reaction meaning that it releases heat as an energy form. Due to the exothermic nature of this experiment, temperature ranges should be monitored throughout the experiment. The overall objective in this experiment is to yield a

Hydroxyl (HO), Hydroperoxyl {H02),Peroxyl (ROO), Alkoxyl (RO) as free radicalsand Hydrogen Peroxide (H2O2),Hypochlorous Acid(HOCL), and Ozone (03).Similarly, the nitrogen derived species aremainly Nitric Oxide (NO), Nitrogen Dioxide (N02), Peroxynitrite Anion(ONOO) and Dinitrogen Trioxide (N2O3) . ROS are produced

It has been 150 years since the first synthetic dye Maurine was discovered by British chemist William Henry Perkin. William Henry initially intended to carry out tease arch aimed at at synthetic route to quinine( the Amit malaria drug).at the time of William Henry analytical tools such as NMR, that organic chemists now use every day to determine what they have made, had not been discovered if Perkin had only had these tools he would have understood that quinine was composed of only carbon, nitrogen, oxygen and hydrogen utilizing combustion analysis which is the burning of the compound in air. Aromatic amine aniline with oxidizing agents such as potassium dichromate (K2Cr2O7) in hopes that the potassium dichromate would add oxygen to aniline

However as SO3- exists in the wine only in very small concentrations, a majority of the antioxidant actions occurs from molecular SO2 reacting with the wine compounds themselves. Firstly, molecular SO2 reverses the oxidation of colourless diphenol to brown o-quinones by binding to and inhibiting PPO, which catalyses the oxidation (refer to figure 3) (Martin, 2011). Molecular SO2 also prevents the oxidation of ethanol by hydrogen peroxide (produced by the oxidation of hydroxyl-phenols) into acetaldehyde (Rotter, 2002) which occurs in the